Catheter-associated urinary tract infection in patients undergoing intensive care unit and its influencing factors
Journal of Behdasht dar Arseh (i.e., Health in the Field),
Vol. 13 No. 2 (1404),
4 January 2026
,
Page 44-50
https://doi.org/10.22037/jhf.v13i2.49572
Abstract
Background and Aims: Urinary tract infections (UTIs) can lead to irreversible complications, reduced quality of life, and increased healthcare costs. Therefore, the present study was conducted to investigate catheter- associated urinary tract infections (CAUTIs) among patients hospitalized in the intensive care unit (ICU).
Materials and Methods: This descriptive study was conducted on 86 patients with catheter-associated urinary tract infections admitted to the ICU of one of the hospitals affiliated with Qom University of Medical Sciences, using a census sampling method. Data were collected using a researcher-designed checklist. Data analysis was performed using SPSS23, applying descriptive statistics, the chi-square test, and the independent t-test. The study was conducted after obtaining approval from the Research Council and ethical clearance from the Ethics Committee of Qom University of Medical Sciences.
Results: The mean age of participants was 67.9 ± 13.9 years. Catheterization duration, antibiotic use, and catheter replacement timing were significantly associated with urinary tract infection (P < 0.001), whereas age, sex, marital status, BMI, smoking, corticosteroid use, and surgical history showed no significant association (P > 0.05).
Conclusion: Based on the study findings, ICU patients with longer catheterization duration, more frequent catheter replacement, and higher antibiotic use experienced a higher incidence of urinary tract infection. Therefore, enhancing staff awareness of proper care, adhering to standard catheter replacement protocols, facilitating earlier catheter removal, and educating clinicians about antibiotic resistance and its consequences are recommended to reduce the risk of urinary tract infections in ICUs.
- Urinary tract infection
- urinary catheter
- Catheter-associated urinary tract infection
- intensive care unit
How to Cite
References
1- Tan CW, Chlebicki MP. Urinary tract infections in adults. Singapore Medical Journal 2016; 57(9):485-90.
2- Salehi M, Robati D, SeyedAlinaghi S M, Seifi A, Aliramezani A, Dehghan Manshadi S A, et al. Clinical and microbiological patterns in critically ill patients with catheter-associated UTI: A report from Iran. The Journal of Infection in Developing Countries 2023; 17(1):129-34.
3- Kranz J, Schmidt S, Wagenlehner F, Schneidewind L. Catheter-associated urinary tract infections in adult patients. Preventive strategies and treatment options. Deutsches Arzteblatt International 2020; 117(6):83-88.
4- Werneburg GT. Catheter-associated urinary tract infections: Current challenges and future prospects. Research and Reports in Urology 2022; 14:109-33.
5- Zhang L, Zhang F, Xu F, Wang Z, Ren Y, Han D, et al. Construction and evaluation of a sepsis risk prediction model for urinary tract infection. Frontiers in Medicine 2021; 8:671184. Doi: 10.3389/fmed.2021.671184.
6- Bavanandan S, Keita N. Urinary tract infection prevention and treatment. Semin Nephrol 2023; 43(5):151468. Doi: 10.1016/j.semnephrol.2023.151468.
7- Mengistu DA, Alemu A, Abdukadir AA, Mohammed Husen A, Ahmed F, Mohammed B. Incidence of urinary tract infection among patients: systematic review and meta-analysis. Inquiry: The Journal of Health Care Organization, Provision, and Financing 2023; 60:469580231168746 .Doi:10.1177/00469580231168746.
8- Van Decker SG, Bosch N, Murphy J. Catheter-associated urinary tract infection reduction in critical care units: a bundled care model. BMJ Open Qual 2021; 10(4):e001534. Doi: 10.1136/bmjoq-2021-001534.
9- Adomi M, Iwagami M, Kawahara T, Hamada S, Iijima K, Yoshie S, et al. Factors associated with long-term urinary catheterisation and its impact on urinary tract infection among older people in the community: A population-based observational study in a city in Japan. BMJ Open. 2019; 9(6):e028371. Doi:10.1136/bmjopen-2018-028371.
10- Gambrill B, Pertusati F, Hughes SF, Shergill I, Prokopovich P. Materials-based incidence of urinary catheter associated urinary tract infections and the causative micro-organisms: systematic review and meta-analysis. BMC Urol 2024; 24(1):186. Doi: 10.1186/s12894-024-01565-x.
11- Shen L, Fu T, Huang L, Sun H, Wang Y, Sun L, et al. 7295 elderly hospitalized patients with catheter-associated urinary tract infection: A case-control study. BMC Infectious Diseases 2023; 23(1):825. Doi: 10.1186/s12879-023-08711-0.
12- Flores-Mireles AL, Walker JN, Caparon M, Hultgren SJ. Urinary tract infections: epidemiology, mechanisms of infection and treatment options. Nature Reviews Microbiology 2015; 13(5):269-84.
13- Sleziak J, Błażejewska M, Duszyńska W. Catheter-associated urinary tract infections in the intensive care unit during and after the COVID-19 pandemic. BMC Infectious Diseases 2025; 25(1):595. Doi: 10.1186/s12879-025-10996-2.
14- Azad MAK, Islam MN, Choudhury MR, Haq SA, Shahin A, Rashid FB, et al. Urinary tract infection in systemic lupus erythematosus: Report from a developing country. Mymensingh Medical Journal 2025; 34(1):141-52.
15- Yajun L, Xuan Z, Juan T, Rui T, Zuyan X, Bingbing Z, et al. Risk factors for catheter-associated urinary tract infection in an intensive care unit: A matched case-control study. BMC Infectious Diseases 2025; 25(1):617. Doi:10.1186/s12879-025-10839-0.
16- Rabi R, Enaya A, Jomaa DM, Dweekat MTZ, Raddad S, Saqfalhait ZT, Abu-Gaber D. Catheter-associated urinary tract infections in critical care: Understanding incidence, risk factors, and pathogenic causes in Palestine. PLoS One 2024; 19(8):e0309755. Doi:10.1371/journal.pone.0309755.
17- Li F, Song M, Xu L, Deng B, Zhu S, Li X. Risk factors for catheter-associated urinary tract infection among hospitalized patients: A systematic review and meta-analysis of observational studies. Journal of Advanced Nursing 2019; 75(3):517-27.
18- Flores-Mireles A, Hreha TN, Hunstad DA. Pathophysiology, treatment, and prevention of catheter-associated urinary tract infection. Topics in Spinal Cord Injury Rehabilitation 2019; 25(3):228-40.
19- Costelloe C, Metcalfe C, Lovering A, Mant D, Hay AD. Effect of antibiotic prescribing in primary care on antimicrobial resistance in individual patients: Systematic review and meta-analysis. Bmj 2010; 340:c2096. Doi:10.1136/bmj.c2096.
20- Patel PK, Advani SD, Kofman AD, Lo E, Maragakis LL, Pegues DA, et al. Strategies to prevent catheter-associated urinary tract infections in acute-care hospitals: 2022 Update. Infection Control & Hospital Epidemiology 2023; 44(8):1209-31.
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