Assessing the Health of Genetically Modified Foods Based on the Ethical Principle of No-harm
Akhlāq-i zīstī i.e., Bioethics Journal,
Vol. 12 No. 37 (1401),
20 June 2022
,
Page 1-16
https://doi.org/10.22037/bioeth.v12i37.35035
Abstract
Background and Aim: The rapid advances of scientists in the field of biotechnology and genetic engineering have made the ethical principle of non-harm in the field of biological sciences a special place. The production of genetically modified foods is one of the latest advances in biotechnology. Today, the debate over the safety and health of genetically modified foods is a controversial issue around the world. The purpose of this article is to evaluate the health of genetically modified foods by emphasizing the ethical principle of not harming humans referring to available evidence.
Methods: The method of this research is descriptive-analytical and the collection of information has been done by library method.
Ethical Considerations: In this article, honesty and trustworthiness have been observed.
Results: Solving the problem of global hunger, improving food quality, improving the economic situation of farmers and maintaining environmental health are the most important benefits of producing genetically modified foods. The production of genetically modified foods has been introduced as a suitable solution to meet human nutritional needs, while the health and safety of these foods are disputed. Opponents do not accept the safety and health of these foods due to scientific disagreement and the potential dangers, and believe that the ethical principle of non-harm is not observed in the production of genetically modified foods. In contrast, proponents, because of the scientific consensus on the safety and health of genetically modified foods, the results of case studies, and the successful experience of the American people, claim the safety and health of genetically modified foods and the harmonization of their production with ethics.
Conclusion: The production of genetically modified foods has significant benefits, but there are many unknowns about the disadvantages of using this technology. The existence of potential hazards in the production of genetically modified foods and scientific uncertainty about the occurrence of these hazards is a reason to implement the principle of caution in the production of these foods.
Please cite this article as:
Alebouyeh A, Razavi MA. Assessing the Health of Genetically Modified Foods Based on the Ethical Principle of No-harm. Akhlaq-i zisti, i.e., Bioethics Journal. 2022; 12(37): e5.
- Genetically Modified Foods; Bioethics; Principle of No-harm; Precautionary Principle
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References
Künnemann R, Epal-Ratjen S. The right to food: A resource manual for NGOs. New York: American Association for the Advancement of Science, Science and Human Rights Programme; 2004. p.69.
Askari M. The effect of transgenic plants on human health through biomedical drugs and foods. Journal of Biosafety. 2013; 2(6): 153-159. [Persian]
Shahadati Moghaddam Z. Transgenic tracking methods. Tehran: Sepehr; 1999. p.10. [Persian]
Bawa A, Anilakumar K. Genetically modified foods: safety, risks and public concerns: A review. Journal of Food Science and Technology. 2013; 50(6): 1035-1046.
Vaughn L. Bioethics: Principles, issues and cases. New York: Oxford University Press; 2010. p.5.
Jahn W. The 4 basic ethical principles that apply to forensic activities are respect for autonomy, beneficence, nonmaleficence and justice. J Chiropr Med. 2011; 10(3): 225-226.
Alsan M. Principles of Bioethics. Tahghighate Hoghoghi. 2007; 137(45): 153-183. [Persian]
Gabbaran M. Convergence of bioethics principles in the field of research with Islamic approach. Research Quarterly in Islamic Ethics. 2018; 11(41): 89-106. [Persian]
Razavi M, Alebouye A. Genetically modified foods and principle beneficence. Ethical Reflections. 2021; 2(1): 26-44. [Persian]
Mohammadi S, Yazdanpanah M. Benefits and Considerations of Transgenic Plants. Journal of Biosafety. 2013; 6(2): 123-132. [Persian]
Economidis I, Cichocka D, Högel J. A decade of EU-funded GMO research (2001-10). European Union: Publications Office; 2010. p.15-16.
American Medical Association. Report 2 of the Council on Science and Public Health: Labeling of Bioengineered Foods. 2012; 20: 245-315.
Fernbach PM, Light N, Scott SE, Inbar Y, Rozin P. Extreme opponents of genetically modified foods know the least but think they know the most. Nat Hum Behav. 2019; 3(3): 251-256.
Snell C, Bernheim A, Bergé JB, Kuntz M, Pascal G, Paris A, et al. Assessment of the health impact of GM plant diets in long-term and multigenerational animal feeding trials: A literature review. Food Chem Toxicol. 2012; 50(3-4): 1134-1148.
Nicolia A, Manzo A, Veronesi F, Rosellini D. An overview of the last 10 years of genetically engineered crop safety research. Crit Rev Biotechnol. 2014; 34(1): 77-88.
Tufarelli V, Selvaggi M, Dario C, Laudadio V. Genetically modified feeds in poultry diet: Safety, performance and product quality. Crit Rev Food Sci Nutr. 2015; 55(4): 562-569.
Bartholomaeus A, Parrott W, Bondy G, Walker K. The use of whole food animal studies in the safety assessment of genetically modified crops: Limitations and recommendations. Crit Rev Toxicol. 2013; 43(sup2): 1-24.
Domingo JL. Safety assessment of GM plants: An updated review of the scientific literature. Food Chem Toxicol. 2016; 95: 12-18.
Blair R, Regenstein JM. GM food and human Health. In: Andersen V. Genetically Modified and Irradiated Food. American: Academic Press; 2020. p.84-85.
Mohsenpoor M, Kahak S, Ghareh-yazi B. Genetic Engineering and Food Security. Strategic Research Journal of Agricultural Sciences and Natural Resources. 2018; 3(2): 195-208. [Persian]
Steinke K, Guertler P, Paul V, Wiedemann S, Ettle T, Albrecht C, et al. Effects of long‐term feeding of genetically modified corn (event MON810) on the performance of lactating dairy cows. J Anim Physiol Anim Nutr (Berl). 2010; 94(5): e185-e193.
Sakamoto Y, Tada Y, Fukumori N, Tayama K, Ando H, Takahashi, et al. A 104-week feeding study of genetically modified soybeans in F344 rats. Shokuhin Eiseigaku Zasshi. 2008; 49(4): 272-282.
Domon E, Takagi H, Hirose S, Sugita K, Kasahara S, Ebinuma H, et al. 26-Week oral safety study in macaques for transgenic rice containing major human T-cell epitope peptides from Japanese cedar pollen allergens. J Agric Food Chem. 2009; 57(12): 5633-5638.
Bhatti F, Asad S, Khan QM, Mobeen A, Iqbal MJ, Asif M. Risk assessment of genetically modified sugarcane expressing AVP1 gene. Food Chem Toxicol. 2019; 130: 267-275.
EFSA Panel on Genetically Modified Organisms (EFSA GMO Panel), Naegeli H, Bresson JL, Dalmay T, Dewhurst IC, Epstein MM, Firbank LG, Guerche P, Hejatko J, Moreno FJ, Mullins E. Assessment of genetically modified maize Bt11× MIR162× MIR604× 1507× 5307× GA21 and subcombinations, for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐DE‐2011‐103). EFSA Journal. 2019;17(4):e05635.
Naegeli H, Bresson JL, Dalmay T, Dewhurst IC, Epstein MM, Firbank LG, Guerche P, Hejatko J, Moreno FJ, Mullins E. Assessment of genetically modified maize MON 89034× 1507× MON 88017× 59122× DAS‐40278‐9 and subcombinations independently of their origin for food and feed uses, import and processing under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2013‐113). EFSA Journal. 2019;17(1):e05521.
Naegeli H, Bresson JL, Dalmay T, Dewhurst IC, Epstein MM, Firbank LG, Guerche P, Hejatko J, Moreno FJ, Mullins E. Assessment of genetically modified maize MON 89034× 1507× NK603× DAS‐40278‐9 and subcombinations independently of their origin for food and feed uses, import and processing, under Regulation (EC) No 1829‐2003 (application EFSA‐GMO‐NL‐2013‐112). EFSA Journal. 2019;17(1):e05522.
Hilbeck A, Binimelis R, Defarge N, Steinbrecher R, Székács A, Wickson F, et al. No scientific consensus on GMO safety. Environ Sci Eur. 2015; 27(1): 1-6.
"Transgenic Plants, Do's and Don'ts" Symposium. Schools of Agriculture and Natural Resources web site. https://www.utcan.ut.ac.ir/fa/news/970. [Persian]
Engdahl W. Seeds of Destruction: The Hidden Agenda of Genetic Manipulation. Tranlated by Daliri GH. 1st ed. Tehran: Ghoghnoos; 2010. p.24. [Persian]
DeFrancesco L. How safe does transgenic food need to be? Nat Biotechnol. 2013; 31(9): 794-802.
Carman J, Zdziarski I, Edwards J, Haynes J. GM crops and the rat digestive tract: A critical review. Environ Int. 2014; 73: 423-433.
Millstone E, Brunner E, Mayer S. Beyond substantial equivalence. Nature. 1999; 401(6753): 525-526.
Bakshi A. Potential Adverse Health Effects of Genetically Modified Crops. J Toxicol Env Heal B. 2003; 6(3): 211-225.
Domingo JL. Toxicity studies of genetically modified plants: A review of the published literature. Crit Rev Food Sci Nutr. 2007; 47(8): 721-733.
Artemis D, Arvanitoyannis I. Health risks of genetically modified foods. Critical Reviews in Food Science and Nutrition. 2009; 49(2): 164-175.
Ozkok GA. Genetically Modified Foods and the Probable Risks on Human Health. Int J Nutr Food Sci. 2015; 4(3): 356-363.
Abbasi M, Razmkhah N, Heydari B. GM food products and toward challenges from the perspective of bioethics and right to food. Akhlaq-i zisti, i.e., Bioethics Journal. 2014; 4(12): 131-164. [Persian]
Hashemi M, Shogaossadati S. Genetically Modified Foods: Opportunities and Challenges. Food Science & Technology. 2010; 7(1): 89-102. [Persian]
Ewen SW, Pusztai A. Health risks of genetically modified foods. The Lancet. 1999; 354(9179): 684.
Árpád Pusztai. Wikipedia web site. Available at: https://www.en.wikipedia.org.
Séralini G, Clair E, Mesnage R, Gress S, Defarge N, Malatesta M, et al. Retracted: Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize. Fd Chem. 2012; 50(11): 4221-4231.
Carman JA, Vlieger HR, Ver Steeg LJ, Sneller VE, Robinson GW, Clinch-Jones CA, et al. A long-term toxicology study on pigs fed a combined genetically modified (GM) soy and GM maize diet. J Org Syst. 2013; 8(1): 38-54.
Carman JA, Zdziarski IM, Edwards JW. Histopathological Investigation of the Stomach of Rats Fed a 60% Genetically Modified Corn Diet. Int J Food Sci Nutr. 2018; 9(06): 763-796.
Compton J, Fanning JB, Nickels AS. Genetically modified products and food allergy: Beliefs, evidence and opportunity. Ann Allergy Asthma Immunol. 2017; 119(3): 198-199.
Dona A, Arvanitoyannis IS. Health risks of genetically modified foods. Crit Rev Food Sci Nutr. 2009; 49(2): 164-175.
Terefe M. Biosafety issues of genetically modified crops: Addressing the potential risks and the status of GMO crops in Ethiopia. Clon Transgen. 2018; 7(2):164.
Tarazona JV, Tiramani M, Reich H, Pfeil R, Istace F, Crivellente F. Glyphosate toxicity and carcinogenicity: A review of the scientific basis of the European Union assessment and its differences with IARC. Arch Toxicol. 2017; 1(8): 2723-2743.
Clausing P, Robinson C, Burtscher-Schaden H. Pesticides and public health: An analysis of the regulatory approach to assessing the carcinogenicity of glyphosate in the European Union. J Epidemiol Community Health. 2018; 72(8): 668-672.
Kogevinas M. Probable carcinogenicity of glyphosate. British Medical Journal Publishing Group. 2019; 365(1613): 1-2.
Robinson C, Holland N, Leloup D, Muilerman H. Conflicts of interest at the European Food Safety Authority erode public confidence. J Epidemiol Community Health. 2013; 67(9): 717-720.
Fluegge K. GM crops and the rat digestive tract: A critical review. Environ Int. 2015; 84: 213-214.
Reply food standards australia newzealand gmo diet pig study. GMO Judy Carman Web site. Available at: https://www.gmojudycarman.org/reply-food-standar ds-australia-new-zealand-gmo-diet-pig-study. Updated Apr 17, 2015.
Varzakas T, Tzanidis T. Genetically modified foods: Risk assessment, legislation, consumer behavior, and ethics. In: Richard K .Encyclopedia of Food and Health. USA: Academic Press; 2014. p.204-210.
Dizon F ,Costa S, Rock C, Harris A, Husk C, Mei J. Genetically Modified (GM) Foods and Ethical Eating. Journal of Food Science. 2016; 81(2): 87-91.
Guida A. The precautionary principle and genetically modified organisms: A bone of contention between European institutions and member states. Journal of Law and the Biosciences. 2021; 8(1): 1-42.
Paull J. Genetically modified organisms (GMOs) as invasive species. Journal of Environment Protection and Sustainable Development. 2018; 4(3): 31-317.
Clark EA. Environmental risks of genetic engineering. Euphytica. 2006; 148(1): 47-60.
Abbasi M, Akrami F. From Transgenic Organisms towards Transhumanism: Necessity of Ethical Assessment and Legislation. Bioethics Journal. 2019; 8(30): 7-8. [Persian]
Herrera I, Antonio J. International law and GMOs: Can the precautionary principle protect biological diversity? Boletín Mexicano de Derecho Comparado. 2007; 40(118): 97-136.
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