Dementia (Alzheimer’s)and its treatment methods in traditional and medical medicine
Tārīkh-i pizishkī (i.e., Medical History),
Vol. 13 No. 46 (1400),
7 Bahman 2021
,
Page 1-14
https://doi.org/10.22037/mhj.v13i46.33765
Abstract
Background and Aim: Texts and works of traditional (Iranian) medicine show that the physicians of this school of medicine, based on their own paradigm in the field of neurology, were familiar with dementia (Alzheimer's). Also the method of treatment and prescription of medicinal plants such as (frankincense, halibut, saffron, amla, etc.) for the treatment of this disease can be seen in the works and writings of physicians such as Razi, Ibn Sina, Ahwazi, etc. Contrary to the paradigm of traditional medicine (and its lack of commitment to the worldview of the four elements and the principles of temperaments and humors in the world), conventional medicine has taken a quantitative and reductionist approach to treating this disease. This study is an attempt to investigate the treatment of Alzheimer's disease using traditional medicine combinations and common medical prescriptions and its purpose is to answer this question: What are the therapeutic similarities between traditional medicine sources and common medical prescription methods?
Materials and Methods: This study is based on a descriptive-analytical method and by taking notes from the advanced medical sources (Al-Hawi, Qanun Fi Al-Tib, Kamel Al-Sina'a, Khalasa Al-Hakma, etc.) in libraries and comparing it with the resources in the database of Magiran publications and Jihad Daneshgahi Scientific Information Database and other new research papers have been formed.
Findings: Chemical analysis and decomposition of herbs and spices prescribed in traditional medicine confirms the fact that these drugs all have more or less different proportions of antioxidant, anti-inflammatory and ... compounds. The most basic antioxidant properties of herbs and herbs are effective in preventing the destruction of brain cells.
Conclusion: The appropriateness and proximity of the chemical structure of drugs prescribed in conventional medicine such as Tacrine, Denpzil, etc. with the compounds in herbs and spices used in traditional medicine, shows a significant and remarkable similarity. This similarity can be researched and carefully considered by researchers in the vicinity of the treatment methods of these two schools of therapy, while maintaining the principles and structural principles of each.
- Antioxidant properties, Amyloid fibers, Dementia (Alzheimer's), Common medicine, Traditional medicine
How to Cite
References
Razi A. Al-Hawi, Vol. 1. Translated by Tabatabaei SM Al-Hawi Pharmacy Co Press: Tehran. 1990; 389: 1527-32. [In Persian]
Aghili Khorasani MH. Khulasa-al-Hikma. Qom: Ismailian Publication. 2006; p. 262. [In Persian]
Madjusi Ahwazi AIA. Kamil al-Sina'ah al-Tabi'ah: Tehran, Research by Institute of Traditional Medicine Revival, Institute of Medical History Studies . 2009; p. 88. [In Persian]
Ibn Sina HbA. Avicenna's Qanoun fi al-Tibb (the Canon of Medicine). Translated by Sharafkandi A, Tehran: Soroush Publication, 2010; p. 261. 366. 675. [In Persian]
Mirheidary R, Saber SS, Shaeiri MR and Fesharaki MG. A survery and Prieritizing of Medical Herbs Effective on Memory Improvement in Iranian Traditional Medicine. Med. Hist. 2019. Mars 22; 10(35): 9-190.
Shojaii A, Ghods R and Abdollahi Fard M. Medical Herbs in Iranian Traditional Medicine for Learning and Memory, African Jornal of Traditional, Complementary and Alternative medicince 2016; 13(2): 199-209.
Jellinger K. Alzheimer 100-highlights in the history of Alzheimer research. Journal of neural transmission. 2006; 113(11): 1603-23.
Davies RR, Hodges JR, Kril JJ, Patterson K, Halliday GM, Xuereb JH. The pathological basis of semantic dementia. Brain. 2005; 128(9): 1984-95.
Tabatabai SMH. Tafseer Al-Meezan. Qom: Allameh Tabatabai Scientific and Intellectual Foundation; 1984; p. 513, 169. [In Persian]
Mohammadi Rayshahri M. Encyclopedia of Medical Hadiths. Translated by Saberi H , Qom: Dar al-Hadith Publication. 2006 pp. 90. 1: 247. 1: 249. 2: 420. [In Arabic]
Wang C-Q, Yang G-Q. Betacyanins from Portulaca oleracea L. ameliorate cognition deficits and attenuate oxidative damage induced by D-galactose in the brains of senescent mice. Phytomedicine. 2010; 17(7): 527-32.
Jawaid T, Shakya AK, Siddiqui HH, Kamal M. Evaluation of Cucurbita maxima extract against scopolamine-induced amnesia in rats: implication of tumour necrosis factor alpha. Z Naturforsch C J Biosci" [jour]. 2014; 69(9-10): 407-17.
Nizami G. Sharafnameh. Edited by V. Dastgerdi. Tehran: Elmi Publications; 1964. [In Persian]
Rumi J. Masnavi Manavi. Rein-al Din Nicholson with the introduction by Mohammad Abbasi, Tehran: Toloe Shariati, Ali (1990) Return Tehran: Elham. 1994. [In Persian]
Ferdowsi AEbMRaMG. The Shahnameh: The Book of Kings. Tehran: Fakhteh. 1995. [In Persian]
Sultana A, Padmaja A. Boswellia serrata Roxb. a traditional herb with versatile pharmacological activity: a review. International Journal of Pharmaceutical Sciences and Research (IJPSR). 2013; 4(6): 2106-17.
Farshchi A, Ghiasi G, Farshchi S, Malek KP. Effects of boswellia papyrifera gum extract on learning and memory in mice and rats. Iranian Journal of Basic Medical Sciences. 2010; 13. 9-15: 239.
Faghihi A, Joghataie M, Darabi S, Mehdizadeh M, Roghani M, Bakhtiari M. Evaluation of Behavioral Effects of Trans-Resveratrol in the Hemi-Parkinsonian Rat Model. Journal of Iranian Anatomical Sciences. 2007; 5(19-20): 107-14. [In Persian]
Emami M, Hosseini A, Saeedi A, Golbidi D, Reisi P, Alaei H. Effect of red grape juice on learning and passive avoidance memory in rats. J Isfahan Med Sch. 2010; 28(104): 1-7. [In Persian]
Siahmard Z, Alaei H, Reisi P, Pilehvarian AA. Evaluation of the Effects of Red Grape Juice on Alzheimer's Disease in Rats. Journal of Isfahan Medical School. 2012; 29(167). [In Persian]
Aghili M. Makhzan-al-Advia. Rahimi R, Shams Ardekani MR, Farjadmand F, editors. Tehran: Tehran University of Medical Sciences; 2009; 165. [In Persian]
Avicenna. Al-Advia Al-Ghalbiyyah1404 AH; p. 78.
Moeeni R, Gorji N, Tahvilzade M, Hamedi S. Comparative description of Amla in traditional medicine and newstudies. Journal of Islamic and Iranian Traditional Medicine. 2015; 6(1): 53-63. [In Persian]
Scartezzini P, Speroni E. Review on some plants of Indian traditional medicine with antioxidant activity. Journal of ethnopharmacology. 2000; 71(1-2): 23-43.
Ashwlayan VD, Singh R. Reversal effect of Phyllanthus Emblica (Euphorbiaceae) Rasayana on memory deficits in mice. Int J Appl Pharm. 2011; 3: 10-5.
Najafi Kakavand M, Oryan S, Nabiuni M, Ghafournian H. The effect of green tea extract memory impairment induced by injection of streptozotocin-induced brain in male Wistar rat. Pajoohandeh Journal. 2015; 20(4): 198-205. [In Persian]
Rajabi M, Parivar K, Nabiouni M, Yaghmaii P. Effect of curcumin on rat embryonic neuroprogenitor cells under in vitro conditions. JOurnal of cell and Tissue, 2014; 4(4); 435-443. [In Persian]
Bagherian A, Mirzaei M, Mirzaei H, Rahmati M. Saffron extract diminishes learning deficits in brain hypoperfusion. Knowledge and Health, 2015; 10(2), 47-55. [In Persian]
Esmaeili MA, Sonboli A. Antioxidant, free radical scavenging activities of Salvia brachyantha and its protective effect against oxidative cardiac cell injury. Food and Chemical Toxicology. 2010; 48(3): 846-53.
Khalifeh S, Ashabi G, Omidpanah A, Khodagholi F, Esmaeili MA. Evaluating the effect of Salvia hydrangea extract on memory improvement, apoptosis reduction and CREB phosphorylation in animal model of Alzheimer’s disease in male rats. Pajoohandeh Journal. 2014; 19(2): 78-85. [Persian]
Kashkari Y. Kannash Fi al-Tibb. Tehran: Iran University of Medical Sciences; 2007; p. 141. [In Persian]
Khaledi S, Ahmadi S. Amyloid Beta and Tau: from Physiology to Pathology in Alzheimer’s disease. Neurosci J Shefaye Khatam. 2016; 4(4): 67-88. [In Persian]
Shbanaiyan G, Rasti Boroujeni E, Shirmardi M. Comparison of the effect of Citrus aurantium and diazepam on preoperative anxiety. Journal of Shahrekord Uuniversity of Medical Sciences. 2009; 13. [In Persian]
Ashrafi M. Common diseases in old age. Qom Journal of the Maktab of Islam 1970: p. 65. [In Persian]
Reid KJ, Martinovich Z, Finkel S, Statsinger J, Golden R, Harter K, et al. Sleep: a marker of physical and mental health in the elderly. The American journal of geriatric psychiatry. 2006; 14(10): 860-6.
Fadaei F. Exploration of Alzheimer's Disease. Archives of Rehabilitation. 2006; 7(2): 76-80. [In Persian]
Hosseinzadeh H, Sadeghnia HR, Ghaeni FA, Motamedshariaty VS, Mohajeri SA. Effects of saffron (Crocus sativus L). and its active constituent, crocin, on recognition and spatial memory after chronic cerebral hypoperfusion in rats. Phytotherapy Research. 2012; 26(3): 381-386.
Sun Z-Z, Chen Z-B, Jiang H, Li L-L, Li E-G, Xu Y. Alteration of Aβ metabolism-related molecules in predementia induced by AlCl3 and d-galactose. Age(Dordr)" [jour] 2009; 31(4): 277-84.
Farbood Y, Zarifkar AH, Dianat M, Sarkaki A, Mousavi M. The protective effect of agmatine against intracerebroventricular streptozotocin-induced memory impairment in male rats. Knowledge and Health J. 2014; 9(3). 70-76[In Persian]
Falah Mohammadi Z, Ebrahimzadeh M. The Effect of OF Allium Paradoxum extract combined with Voluntary wheel running on brain amyloid beta (Aβ1-42) levels in diabetic male rats. Sport Biosciences J. 2013; 5(16): 42. [In Persian]
Bush AI. Therapeutic targets in the biology of Alzheimer's disease. Current Opinion in Psychiatry. 2001; 14(4): 341-8.
Francis PT, Palmer AM, Snape M, Wilcock GK. The cholinergic hypothesis of Alzheimer’s disease: a review of progress. Journal of Neurology, Neurosurgery and Psychiatry. 1999; 66(2): 137-47.
Johannsen P. Medical treatment of Alzheimer's disease. Ugeskrift for laeger. 2006; 168(40): 3424-9.
Khalaj-kondori M, Amiri S, and Shaikhzadeh-Hesari F. Comparing the effects of rivastigmin and aqueous extract of olibanum on gene expression of amyloid precursor protein in rats treated with aluminum chloride. Journal of Police Medicine. 2016; 4(4): 279-86.
Shukitt-Hale B, Carey A, Simon L, Mark DA, Joseph JA. Effects of Concord grape juice on cognitive and motor deficits in aging. Nutrition. 2006; 22(3): 295-302.
Rasouli B, Hosseinzadeh M, Hosseinzadeh H, Ghafari Moghadam Gh. Extract of frankincense and memory enhancement. Journal of University of Tarbiat Moalem' Sciences 2001; 1(1): 1-13.
Hamidivafa F and M. M. Ibn Sinaw and Jorjani's view on the health of the elderly, Journal of Medicine and Cultivation, 2008; 67: 70-77.
Chapman SB, Aslan S, Spence JS, DeFina LF, Keebler MW, Didehbani N, et al. Shorter term aerobic exercise improves brain, cognition, and cardiovascular fitness in aging. Frontiers in aging neuroscience J. 2013; 5: 75.
- Abstract Viewed: 1920 times
- pdf (فارسی) Downloaded: 1100 times