Archives of Advances in Biosciences

Abstract

Extremely low frequency (ELF) and Radio frequency (RF) electromagnetic field may affect biological systems by raising generation free radicals by decline activities of glutathione peroxidase dismutase or increase in the lifetime of free radicals with inhibited pretreatment of cells antioxidant like that alpha tocopherol. ELF and  RF electromagnetic  field maycan damaged DNA  with raising level  hydroxyl radicals in cells and  it is  can interact DNA and form mainly 8-hydroxy-2′–deoxyguanosine( 8-OHdG) adducts. Many study showed   Electromagnetic field radiation(EMF) can change gene expression and conformation of protein. It may declineexpression of some genes such as superoxide dismutase orraise expressionof certain genes such as Hsps (heat shock proteins). ELF and RFelectromagnetic field   can effects on homeostasis Ca²⁺ and alteration in important cellular and molecular processes such as differentiation, proliferation, gene expression, cytoskeletal reorganization and metabolism. Use of radio frequency electromagneticfield onsatellite jamming in Iran and some country may can harmful to human health and it could be a risk factor for cancer.