Social Innovation: A Critical Mechanism for Translating Genetic Research into Public Health Practice
Archives of Advances in Biosciences,
Vol. 17 No. 1 (2026),
28 April 2026
,
Page 1-17
https://doi.org/10.22037/aab.v17i1.52108
Abstract
Context: Advances in genetics, genomics, and precision medicine have created unprecedented opportunities to improve population health. However, translating these scientific breakthroughs into equitable public health practice remains a major challenge, particularly in low- and middle-income countries (LMICs), where financial, organizational, policy, and workforce barriers limit implementation. This review examines how social innovation can bridge the gap between genomic discoveries and public health impact.
Evidence Acquisition: A narrative review of the literature was conducted using major scientific databases, including PubMed, Scopus, Web of Science, and Google Scholar, together with reports from international organizations. Relevant evidence on social innovation, public health genomics, precision medicine, implementation science, and health equity was identified, critically appraised, and synthesized, with particular attention to experiences from LMICs and Iran.
Results: The evidence indicates that successful translation of genomics into public health depends not only on technological advances but also on social innovation. Four complementary domains were identified: innovative service delivery, sustainable financing mechanisms, participatory governance, and supportive policy and regulatory frameworks. International case studies demonstrate that approaches such as task-shifting, tele-genetics, community engagement, and digital health platforms can substantially improve equitable access to genomic services. Iran possesses important strengths, including an extensive primary healthcare network, a nationwide newborn screening program, and established community health workers (Behvarzes). Nevertheless, workforce shortages, fragmented genomic infrastructure, financing limitations, and policy inconsistencies remain major barriers to implementation.
Conclusion: : Social innovation is a critical mechanism for translating genomic research into equitable public health practice. Integrating genomics within existing primary healthcare systems, strengthening governance, investing in workforce capacity, and promoting community participation can accelerate the implementation of precision public health, particularly in Iran and other LMICs.
- Social Innovation
- Public Health Genomics
- Precision Medicine
- Health Equity
- Community Engagement
How to Cite
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