Evaluating the Anti-Inflammatory Properties of Nettle in Traditional Medicine and Modern Medicine
Tārīkh-i pizishkī i.e., Medical History,
Vol. 10 No. 36 (1397),
27 November 2019
,
Page 65-72
https://doi.org/10.22037/mhj.v10i36.24464
Abstract
Background and Aim: Inflammation occurs due to systematic effort of body for self-protection and the aim is to eliminate the damaging agents and to launch the healing process. When a damaging factor stimulates the body, an attempt is made by the body to preclude the agent and this would cause the inflammation. Long-term use of anti-inflammatory drugs could cause serious complications like digestive disorders and even stomach ulcers. The side effects of chemical drugs have directed more attentions to the herbal medicines, in that these types of drugs not only have less side effects but are able to could mitigate the excessive effects of chemical ones and reinforce their therapeutic effects.
Materials and Methods: In the present paper, regarding the irrefutable evidences of traditional medicine was anti-inflammatory properties of nettle especially prostatic inflammation; the extracted alcoholic of the plant was evaluated fors its anti-inflammatory property at various concentrations using the inhibition test of denaturation of the bovine serum protein at 51°C. Data analysis was performed using the SPSS Software, version 19 through variance analyzing method. P<0.05 was considered as the significant difference.
Ethical Considerations: Integrity and trustworthiness were observed in analyzing and Reporting and publishing the results.
Findings: According to the results abstained from the alcoholic extract of nettle, this plant possesses anti-inflammatory properties, the range of which according to the inhibition test of denaturation of bovine serum protein at 1000 and 100 microgram/millimeter of concentration is the minimum and maximum, respectively.
Conclusion: The results were consistent with traditional medicine and further assessment we could benefit from the alcoholic extract of the said plant as an anti-inflammatory drug.
Please cite this article as: Khosroyar S, Haghparast Cheshmeh Ali M. Evaluating the Anti-Inflammatory Properties of Nettle in Traditional Medicine and Modern Medicine. Med Hist J 2018; 10(36): 65-72.
- Inflammation, Nettle, Traditional Medicine
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References
Farkhani A. Isfahan university of medical sciences. Health Magazine 2013; 34: 23-25. [Persian]
Baghdikian B, Lanhers M, Fleurentin JO. An analytical study. Planta Med 2016; 63: 171-176. [Persian]
Pieroni A, Janiak V, Dürr CM, Lüdeke S, Traschsel E, Heinrich M. In vitro antioxidant activity of non-cultivated vegetables of ethnic Albanians in southern Italy. Phytotherapy Research 2002; 16(5): 467-473.
Matthias A, Penman KG, Matovic NJ, Bone KM, De Voss JJ, Lehmann RP. Bioavailability of Echinacea constituents; Caco-2 monolayers and pharmacokinetics of the alkylamides and caffeic acid conjugates. Molecules 2005; 10(10): 1242-1251.
Ahmed S, Anuntiyo J, Malemud CJ, Haqqi TM. Biological Basis for the Use of Botanicals in Osteoarthritis and Rheumatoid Arthritis: A Review. Complementary and Alternetive Medicine 2005; 2(3): 301-308.
Klingelhoefer S, Obertreis B, Quast S, Behnke B. Antirheumatic effect of IDS 23, a stinging nettle leaf extract, on in vitro expression of T helper cytokines. Journal of Rheumatology 1999; 26(12): 2517-2522.
Blumenthal M, Goldberg A, Brinckmann J. Herbal Medicine Expanded Commission E Monographs. Edited by Blumenthal M, Goldberg A, Brinckmann J. USA: Integrative Medicine Communications; 2000. p.371-372.
Shariat S. Hadi xtraction & xtracting active ingredients from medicinal plants & indntification methods & their volution. Isfahan: Publication (Maei); 1998. p.153-188. [Persian]
Ramic S, Murko D, Alibalic S. An investigation of chlorophyll and tannin contents in the leaves of stinging-nettle (Urtica dioica L.) during the growing season. Rad Pojopr Fak Univ Sarajeva 1987; 35(39): 85-88.
Sakat S, Juvekar AR, Gambhire MN. In vitro antioxidant and antiinflammatory activity of methanol extract of oxalis corniculata Linn. I J Pharm Sci 2010; 2: 146-155.
Govindappa M, Sadananda TS, Channabasava R, Raghavendra V. In vitro anti-inflammatory. International Journal of Pharma and Biosciences 2011; 2: 275-283.
Pesca-Manca L, Parvu AE, Parvu M, Taamas M, Buia R, Puia M. Effects of Melilotus officinalis on acute inflammation. Phytother Res 2002; 16(4): 316-319.
Abdel-Moein NM, Mohamed DA, Hanfy EA. Evaluation of the anti-inflammatory and anti-arthritic of some plant extracts. International Journal of Fats and Oils 2001; 62(4): 365-374. [Persian]
Leelaprakash G, Mohan Dass S. In Vitro anti-inflammatory activity of methanol extract of enicostemma axllare. International Journal of Drug Development & Research 2010; 3: 189-197.
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