Keratoacanthoma: A Case Report, An Update, and Review of Literature
Journal of Dental School,
Vol. 38 No. 4 (2020),
18 December 2021
,
Page 165-167
https://doi.org/10.22037/jds.v38i4.35198
Abstract
Objectives This study aimed to review and briefly discuss the literature about keratoacanthoma (KA) and present a case of KA of the facial skin under the right eye with over 6-months of follow-up after removal.
Case: An 86-year-old healthy man was referred to a private clinic with a 5-6-week history of a rapidly growing, crateriform nodule with a central hemorrhagic crust on the facial skin under the right eye. Surgical excision was the treatment chosen to differentiate the lesion from squamous cell carcinoma (SCC). Thereafter, the lesion was completely excised. Histopathological analysis confirmed the diagnosis of KA. During over 6 months of follow-up after removal of the lesion, the patient was completely satisfied with the process of treatment, and no recurrence occurred.
Conclusion Solitary KA lesions are commonly found on sun-exposed skin in older adults, similar to our case. Early diagnosis and treatment could reduce the risk of malignancy and recurrence. Moreover, close follow-up of patients with a history of KA is needed, because the possibility of developing a new KA lesion, due to trauma or medical and cosmetic procedures, especially on the UV damaged skin, still exists.
- Keratoacanthoma
- Carcinoma
- Squamous Cell; Skin
How to Cite
References
Ugwu N, Kibbi N. Successful Treatment of Multiple Post-Operative Keratoacanthomas with Topical 5-Fluorouracil. SKIN. 2021;5(1):46-50.
de Souza Damascenoa YE, de Carvalhoa WR, Netoa NC, Vieirab EH, de Souzaa LL, Pontesa HA. Head and neck giant keratoacanthoma: a case report. Rev Port Estomatol Med Dent Cir Maxilofac. 2018;59(2):115-8.
Joshi S. Genotypic and phenotypic characterization of keratoacanthoma and possible distinguishing features from cutaneous squamous cell carcinoma. 2021 Mar:14; Chap 1:10-12.
Snarskaya ES, Shnakhova LM, Gomich DA, Vasileva KD. Atypical kerato acanthoma: a case report. Rus j skin ven dis. 2020;23(6): 364-372.
Xiao H, Hooper PB, Umphress BA, Wolverton JE. Keratoacanthoma centrifugum marginatum. Dermatol Online J. 2021 Mar 15;27(3):13030.
Yehya M, Batchou A, Simpson T. Longstanding Eruptive Keratoacanthoma of the Neck Arising From a Tattoo. J Dermatol Res Ther. 2020; 6(1):084.
Elder DE, Bastian BC, Cree IA, Massi D, Scolyer RA. The 2018 World Health Organization Classification of Cutaneous, Mucosal, and Uveal Melanoma: Detailed Analysis of 9 Distinct Subtypes Defined by Their Evolutionary Pathway. Arch Pathol Lab Med J. 2020;144(4):500-22.
Havenith R, de Vos L, Fröhlich A, Braegelmann C, Sirokay J, Landsberg J, et al. Grzybowski's Generalized Eruptive Keratoacanthomas in a Patient with Terminal Kidney Disease-An Unmet Medical Need Equally Ameliorated by Topical Imiquimod Cream and Lapacho Tea Wraps: A Case Report. Dermatol Ther (Heidelb). 2021;11(2):625-638.
Takai T. Advances in histopathological diagnosis of keratoacanthoma. J Dermatol. 2017;44(3):304-14.
Tisack A, Fotouhi A, Fidai C, Friedman BJ, Ozog D, Veenstra J. A Clinical and Biologic Review of Keratoacanthoma. Br J Dermatol. 2021;185(3):487-98.
Nirenberg A, Steinman H, Dixon A. Keratoacanthoma: Update on the Debate. Am J Dermatopathol. 2021;43(4):305-7.
Takayama E, Yoshioka A, Takai T, Goto K. A case of Muir-Torre syndrome with a keratoacanthoma and sebaceous neoplasms: Clinicopathological features and a speculation on the pathogenesis of cutaneous tumor type. J Dermatol. 2021;48(5):690-4.
Laamari K, Oukarfi S, Elloudi S, Douhi Z, Baybay H, Mernissi FZ, et al. Keratoacanthoma or squamous cell carcinoma. Our Dermatol Online. 2020;11(e): e76.1-76.3.
da Silva AD, Damante JH, Taveira LA, Tjioe KC. Solitary keratoacanthoma of the lip vermilion: case report and comprehensive review of literature. J. Oral Diag. 2019;4(1):1-6.
Downing MB, Prouty M, Wu DJ, Rajpara A. High-Potency Topical Steroid Treatment of Multiple Keratoacanthomas Associated With Prurigo Nodularis. Cutis J. 2021;107(4):221-2.
Nagarajan P. Differentiating keratoacanthoma from squamous cell carcinoma-In quest of the holy grail. J Cutan Pathol. 2020;47(4):418-20.
Bilgen F, Ural A, Bekerecioğlu M. A sheep in wolf’s clothing, or a wolf in sheep’s clothing? Keratoachantoma. Namık Kemal Tıp Dergisi. 2020; 8(2): 107-116.
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