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  3. Vol. 9 No. 1 (2026): IPA- Vol 9, Issue 1
  4. Review article

Vol. 9 No. 1 (2026)

October 2026

Green Synthesis of Nanoparticles for Pharmaceutical Applications: A Sustainable Approach

  • Hina Shaikh

International Pharmacy Acta, Vol. 9 No. 1 (2026), 11 October 2026 , Page e1: 1-3
https://doi.org/10.22037/ipa.v9i1.50862 Published: 2026-01-15

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Abstract

Nanotechnology has significantly influenced pharmaceutical sciences by enabling advanced platforms for drug delivery, diagnostics, and therapeutics. Conventional nanoparticle (NP) synthesis methods often rely on toxic chemicals and high-energy inputs and generate hazardous by-products, which may limit biomedical translation. Green synthesis offers an alternative approach by employing biological entities such as plant extracts, microorganisms, algae, and natural polymers as reducing and stabilizing agents. This review summarizes major green synthesis strategies for metallic (e.g., silver, gold, zinc oxide, and iron oxide) and polymeric nanoparticles, outlines general formation mechanisms, and highlights commonly used physicochemical characterization techniques. Selected pharmaceutical and biomedical applications—including drug delivery, antimicrobial therapy, anticancer applications, wound healing, and diagnostics—are discussed with representative examples from the literature. Finally, key challenges related to reproducibility, scalability, regulatory compliance, and future research directions are critically examined. Overall, green nanotechnology represents a promising but still evolving route toward more sustainable pharmaceutical nanomaterials.

Keywords:
  • Green synthesis
  • Nanoparticles
  • Sustainable nanotechnology
  • Drug delivery
  • Phytochemicals
  • Eco friendly synthesis
  • Biocompatibility
  • Translational nanomedicine
  • IPA-2026 Vol9i1-e1

How to Cite

Shaikh, H. (2026). Green Synthesis of Nanoparticles for Pharmaceutical Applications: A Sustainable Approach. International Pharmacy Acta, 9(1), e1: 1–3. https://doi.org/10.22037/ipa.v9i1.50862
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References

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2. Kumar V, et al. Green synthesis of silver nanoparticles and their biomedical applications. J Nanobiotechnol. 2020;18(1):1–15.

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4. Raman S, et al. Marine algae mediated synthesis of nanoparticles: biomedical potential. J Appl Phycol. 2022;34(2):789–805.

5. Singh P, et al. Phytochemical mediated green synthesis of nanoparticles. Front Chem. 2021;9:643203.

6. Lithi IJ, Nakib KIA, Chowdhury AMS, Hossain MS. A review on the green synthesis of metal (Ag, Cu, Au) and metal oxide (ZnO, MgO, Co₃O₄, TiO₂) nanoparticles using plant extracts for developing antimicrobial properties. Nanoscale Adv. 2025;7:2446–2473.

7. Shahzadi S, Fatima S, Ul Ain Q, Shafiq Z, Janjua MRSA. A review on green synthesis of silver nanoparticles (SNPs) using plant extracts: a multifaceted approach in photocatalysis, environmental remediation, and biomedicine. RSC Adv. 2025;15:3858–3903.

8. Borehalli Mayegowda R, Roy NG, Pandit R, Alghamdi S, Almehmadi M, Allahyani S, et al. Eco-friendly synthesized nanoparticles as antimicrobial agents: an updated review. [Journal name not specified]. 2023.

9. Samuel MS, Ravikumar M, John JA, Selvarajan E, Patel H, Chander PS, et al. A review on green synthesis of nanoparticles and their diverse biomedical and environmental applications. Catalysts. 2022;12(5):459.

10. Mirzaei H, Darroudi M. Zinc oxide nanoparticles: biological synthesis and biomedical applications. Ceram Int. 2017;43(1):907–914.

11. Das S, Chakraborty T. A review on green synthesis of silver nanoparticles and zinc oxide nanoparticles from different plant extracts and their antibacterial activity against multidrug-resistant bacteria. J Innov Pharm Biol Sci. 2018;5(4):63–73.

12. Singh, P., et al. (2021). Phytochemical mediated green synthesis of nanoparticles. Frontiers in Chemistry, 9, 643203.

13. Borehalli Mayegowda, R., Roy, N. G., Pandit, Alghamdi, Almehmadi, Allahyani, Awwad, Sharma (2023). Eco friendly synthesized nanoparticles as antimicrobial agents: An updated review.

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