Background and Objectives: In the era of global industrialization, enzymes are being used extensively in the various sectors including food processing. Owing to the high price of enzymes, various initiatives have been undertaken by the R&D sector for the development of new processes or improvement in the existing processes for production of cost effective enzymes. With the advancement in the field of biotechnology, different bioprocesses are being used for utilization of different agro-industrial residues for the production of various enzymes. This review focuses on different types of agro-industrial wastes and their utilization in the production of enzymes. The present scenario as well as the future scope of utilization of enzymes in the food industry has also been discussed.
Results and Conclusion: The regulations from the various governmental as well as environmental agencies for the demand of cleaner environment have led to the advancement in various technologies for utilization of the wastes for the production of value-added products such as enzymes. Among the different types of fermentation, maximum work has been carried under solid state conditions by batch fermentation. The research has indicated the significant potential of agro-industrial wastes for production of food-grade enzymes in order to improve the economics of the process.
Conflict of interests: The authors declare no conflict of interest.
Awan MS, Khan SA, Rehman ZU, Saleem A, Rana SM. Influence of nitrogen sources on production of β-galactosidase by Aspergillus niger. Afr J Biotechnol. 2010; 9: 2918-2922.
Panesar PS, Marwaha SS, Chopra HK. Enzymes in food processing: Fundamentals and potential applications. IK Publishers, New Delhi, 2010.
Machielsen R, Dijkhuizen S, van der Oost J. Improving enzyme performance in food applications. In: Rastall R. Novel enzyme technology for food applications, CRC Press, Boca Raton, New York, 2007; 16-42.
Trevan MD. Enzyme Production, In: Trevan MD, Boffey S, Goulding KH, Stanbury P. Biotechnology: The biological principles, Tata McGraw Hill Publishing Company Ltd, New Delhi, 1988; pp. 155-177.
Aunstrup K. Industrial production of proteolytic enzymes. Ind Aspects Biochem. 1974; 30(1):23-46.
Rigo E, Ninowa JL, Di Luccio M, Oliveira JV, Polloni A, Remonatto D, Arbter F, Vardanega R, de Oliveira D, Treichel H. Lipase production by solid fermentation of soybean meal with different supplements. LWT: Food Sci Technol. 2010; 43:1132-1137.
Salihu A, Alama MZ, M. Ismail AbdulKarim MI, Salleh HM. Optimization of lipase production by Candida cylindracea in palm oil mill effluent based medium using statistical experimental design. J Mol Catal B Enzym. 2011; 69:66-73.
Rodríguez-Couto S. Exploitation of biological wastes for the production of value-added products under solid-state fermentation conditions. Biotechnol J. 2008; 3:859-870.
Ezejiofor TIN, Enebaku UE, Ogueke C. Waste to wealth-value recovery from agro-food processing wastes using biotechnology: A review. Br Biotechnol J. 2014; 4(4):418-481.
Graminha EBN, Goncalves AZL, Pirota RDPB, Balsalobre MAA, da Silva R, Gomes E. 2008. Enzyme production by solid-state fermentation: Application to animal nutrition. Anim Food Sci Technol. 2008; 144:1-22.
Mussatto SI, Ballesteros LF, Martins SF, Teixeira JA. Use of agro-industrial wastes in solid state fermentation processes. In: Show KY, Guo X. Industrial waste. Intech, Europe. 2012; 121-140.
Fatima B, Hussain Z, Khan MA. Utilization of agro-industrial waste residues for the production of amylase from Aspergillus oryzae IIB-62014. Br. Biotechnol J. 2014; 4(4): 350-365.
Cara C, Ruiz E, Oliva JM, Sa´ez F, Castro E. Conversion of olive tree biomass into fermentable sugars by dilute acid pretreatment and enzymatic saccharification. Bioresour Technol. 2008; 99:1869-1876.
Joshi VK, Devrajan A. Ethanol recovery from solid state fermented apple pomace and evaluation of physico-chemical characteristics of residue. Nat Prod Radiance. 2008; 7:127-132.
William PT. Water treatment and disposal. 2005.John Willy (eds.)
Miljkovic D, Bignami GS. Nutraceuticals and methods of obtaining nutraceuticals from tropical crops. USA. 2002. Application number: 10/992.502. Published In. Google Patent.
Wilkins MR, Suryawati L, Maness NO, Chrz D. Ethanol production by Saccharomyces cerevisiae and Kluyveromyces marxianus in the presence of orange-peel oil. World J Microbiol Biotechnol. 2007; 23(8):1161–1168.
Mirzaei-Aghsaghali A, Maheri-Sis N. By-products from fruits and vegetable generation, characteristics and their nutritional value. Proceeding of Third national congress of recycling and reuse of renewable organic resources in agriculture. 2008; 13-15 May, Isfahan, Iran.
Boucque CV, Fiems LO. Vegetable by-products of agro-industrial origin. Livestock Prod Sci. 1988; 19:97-135.
Schieber A, Stintzing FC, Carle R. By-products of plant food processing as a source of functional compounds-Recent developments. Trends Food Sci Technol. 2001; 12:401-413.
Fernández-López J, Sendra E, Sayas-Barberá E, Navarro C, Pérez-Alvarez JA. Physico-chemical and microbiological profiles of “salchich” (Spanish dry-fermented sausage) enriched with orange fiber. Meat Sci. 2008; 80:410-417.
AWARENET. Handbook for the prevention and minimization of waste and valorization of by-products in European agro-food industries. 2001-2004.
Moongngarm A, Daomukda N, Khumpika S. Chemical compositions, phytochemicals, and antioxidant capacity of rice bran, rice bran layer, and rice germ. APCBEE Procedia. 2012; 2:73-79.
Qureshi ME, Wegener MK, Mallawaarachchi T. The economics of sugar mill waste management in the Australian Sugar Industry: Mill mud case study. 45th Annual Conference of the Australian Agricultural and Resource Economics Society, Adelaide, South Australia, 23-25 January 2001
Solomon, SK. Environmental pollution and its management in sugar industry in India: An appraisal. Sugar Technol. 2005; 7:77-81.
Paturau, JM. By-products of the cane sugar industry, 2nd edn, p. 365. Elsevier, Amsterdam, The Netherlands. 1982.
Marwaha SS, Kennedy JF. Review: whey-pollution problem and potential utilization, Int J Food Sci Technol. 1988; 23:323-336.
Panesar PS, Kennedy JF. Biotechnological approaches for the value addition of whey. Crit Rev Biotechnol. 2012; 32(4): 327-348.
Mohanrao GJ, Subrahmanyam PVR. Sources, flows and characteristics of dairy wastes. Indian J Envt Health. 1972; 14:207-217.
Shete BS, Shinkar NP. Dairy industry wastewater sources, characteristics & its effects on environment. Int J Current Engg Technol. 2013; 3(5):1611-1615.
White JS, Yohannan BK, Walker GM. Bioconversion of brewers spent grain to bioethanol. FEMS Yeast Res. 2008; 8(7):1175-1184.
Mussatto SI, Rocha GJM, Roberto IC. Hydrogen peroxide bleaching of cellulose pulp obtained from brewers spent grain. Cellulose. 2008; 15:641-649.
Pandey A, Soccol CR, Mitchell D. New developments in solid-state fermentation I. bioprocesses and applications. Process Biochem. 2000; 35:1153-1169.
Alkorta I, Garbisu G, Llama MJ, Serra JL. Industrial applications of pectic enzymes: A review. Process Biochem. 1998; 33:21-28.
Hoondal GS. Microbial alkaline pectinases and their industrial applications: A review. Appl Microbiol Biotechnol. 2002; 59:409-418.
Boccas F, Roussos S, Gutierrez M, Serrano L, Viniegra GG. Production of pectinase from coffee pulp in solid state fermentation system: selection of wild fungal isolate of high potency by a simple three-step screening technique. J Food Sci Technol. 1994; 31:22-26.
Castilho LR, Alves TLM, Medronho RA. Recovery of pectinolytic enzymes produced by solid state culture of Aspergillus niger. Process Biochem 1999; 34:181-186.
Castilho LR, Alves TLM, Medronho RA. Production and extraction of pectinases obtained by solid state fermentation of agro-industrial residues with Aspergillus niger. Bioresour Technol. 2000; 71:45-50.
Hours RA, Voget CE, Ertola RJ. Some factors affecting pectinase production from apple pomace in solid states cultures. Biol wastes 1988; 24:147-157.
Hang YD, Woodanms EE. Production of fungal polygalacturonase from apple pomace. Lebensm Wiss U Technol. 1994; 27:194-196.
Garzon CG, Hours RA. Citrus waste: an alternative substrate for pectinase production in solid-state culture. Bioresour Technol. 1992; 39:93-95.
Schwan RF, Cooper RM, Wheals AE. Endopolygalacturonase secretion by Kluyveromyces marxianus and other cocoa pulp-degrading yeasts. Enzyme Microb Technol. 1997; 21:234-244.
Acuna-Arguelles ME, Gutierrez-Rojas M, Viniegra-Gonzales G, Favela-Torres E. Effect of water activity on exo-pectinase production by Aspergillus niger CH4 on solid state fermentation. Biotechnol Lett. 1994; 16:23-28.
Martins ES, Silva D, Da Silva R, Gomes E. Solid state production of thermostable pectinases from thermophilic Thermoascus aurantiacus. Process Biochem. 2002; 37:949-954.
Rosales E, Couto SR, Sanroman A. New uses of food waste: application to laccase production by Trametes hirsute. Biotechnol Lett. 2002; 24:701-704.
De Gregorio A, Mandalari G, Arena N, Nucita F, Tripodo MM, Lo Curto RB. SCP and crude pectinase production by slurry-state fermentation of lemon pulps. Bioresour Technol. 2002; 83:89-94.
Silva D, Tokuioshi K, da Silva Martins E, Da Silva R, Gomes E. Production of pectinase by solid-state fermentation with Penicillium viridicatum RFC3. Process Biochem. 2005; 40: 2885-2889.
Patil SR, Dayanand A. Production of pectinase from deseeded sunfower head by Aspergillus niger in
submerged and solid-state conditions. Bioresour Technol. 2006; 97:2054-2058.
Giese EC, Dekker RFH, Barbosa AM. Orange bagasse as a substrate for the production of pectinase and laccase by Botryosphaeria rhodina MAMB-05 in submerged and solid state fermentation. Bioresources. 2008; 3(2):335-345.
Martin N, Guez MAU, Sette LD, Da Silva R, Gomes E. Pectinase production by a Brazilian thermophilic fungus Thermomucor indicae_seudaticae n31 in solid-state and submerged fermentation. Mikrobiologiia 2010; 79(3):321-328.
Ahmed SA, Mostafa FA. Utilization of orange bagasse and molokhia stalk for production of pectinase enzyme. Braz J Chem Engg. 2013; 30(3): 449 – 456.
Ahmed I, Zia MA, Hussain MA, Akram Z, Naveed MT, Nowrouzi A. Bioprocessing of citrus waste peel for induced pectinase production by Aspergillus niger; its purification and characterization. J Radiat Res Appl Sci. 2016; 9(2): 148-154.
Embaby AM, Masoud AA, Marey HS, Shaban NZ, Ghonaim TM. Raw agro-industrial orange peel waste as a low cost effective inducer for alkaline polygalacturonase production from Bacillus licheniformis SHG10. SpringerPlus. 2014; 3:1-13.
Biz A, Finkler ATJ, Pitol LO, Medina BS, Krieger N, Mitchell DA. Production of pectinases by solid-state fermentation of a mixture of citrus waste and sugarcane bagasse in a pilot-scale packed-bed bioreactor. Biochem Engg J. 2016; 111:54-62.
Poondla V, Yannam SK, Gummadi SN, Subramanyam R, Obulam VSR. Enhanced production of pectinase by Saccharomyces cerevisiae isolate using fruit and agro-industrial wastes: Its application in fruit and fiber processing. Biocatal Agric Biotechnol. 2016; 6:40-50
Mulimani VH, Patil GN, Ramalingam. α-Amylase production by solid-state fermentation: a new practical approach to biotechnology courses. Biochem Educ. 2000; 28:161-163.
Ramachandran S, Patel AK, Nampoothiri KM, Francis F, Nagy V, Szakacs G, Pandey A. Coconut oil cake-a potential raw material for the production of a-amylase. Bioresour Technol. 2004; 93:169-174.
Kunamneni A, Kumar KS, Singh S. Response surface methodological approach to optimize the nutritional parameters for enhanced production of -amylase in solid state fermentation by Thermomyces lanuginosus. Afr J Biotechnol. 2005; 4(7):708-716.
Sodhi HK, Sharma K, Gupta JK, Soni SK. Production of a thermostable α-amylase from Bacillus sp. PS-7 by solid state fermentation and its synergistic use in the hydrolysis of malt starch for alcohol production. Process Biochem. 2005; 40:525-534.
Kammoun R, Naili B, Bejar S. Application of a statistical design to the optimization of parameters and culture medium for α- amylase production by Aspergillus oryzae CBS 819.72 grown on gruel (wheat grinding by-product). Bioresour Technol. 2008; 99: 5602-5609.
Mukherjee AK, Borah M, Rai SK. To study the influence of different components of fermentable
substrates on induction of extracellular α-amylase synthesis by Bacillus subtilis DM-03 in solid-state fermentation and exploration of feasibility for inclusion of α-amylase in laundry detergent formulations. Biochem Engg J. 2009; 43:149-156.
Babu KR, Satyanarayana T. Alpha-amylase production by thermophilic Bacillus coagulans in solid state fermentation, Process Biochem. 1995; 30:305-309.
Singh R, Kapoor V, Kumar V. Utilization of agro-industrial wastes for the simultaneous production of amylase and xylanase by thermophilic actinomycetes. Braz J Microbiol. 2012; 1545-1552.
Sahnoun M, Kriaa M, Elgharbi F, Ayadi DZ, Bejar S, Kammoun R. Aspergillus oryzae S2 alpha-amylase production under solid state fermentation: Optimization of culture conditions. Int J Biol Macromol. 2015; 75:73-80.
Bhange K, Chaturvedi V, Bhatt R. Simultaneous production of detergent stable keratinolytic protease, amylase and biosurfactant by Bacillus subtilis PF1 using agro industrial waste. Biotechnol Reports. 2016; 10:94-104.
lanco S, urive OP, P rez S , Montes , Guerra NP. Simultaneous production of amylase and proteases by Bacillus subtilis in brewery wastes. Braz J Microbiol. 2016; doi:10.1016/j.bjm.2016.04.019.
Shraddha, Shekher R, Sehgal S, Kamthania M, Kumar A. Laccase: Microial sources, production, purification and potential biotechnological applications. Enzyme Res. 2011; 2011:1-11.
Bourbannais R, Paice MG. Oxidation of non-phenolic substrates. An expanded role for laccase in lignin biodegradation. FEBS Lett. 1990; 267(1): 99-102.
Abadulla E, Tzanov T, Costa S, Robra KH, Cavaco-Paulo A, Gubitz GM. Decolorization and detoxification of textile dyes with laccase from Trametes hirsuta. Appl Environ Microbiol. 2000; 66(8):3357-3362.
Lorenzo M, Moldes D, Rodriguez-Cuoto, S, Sanroman A. Improving laccase production by employing different lignocellulosic wastes in submerged cultures of Trametes versicolor. Bioresour Technol. 2002; 82:109-113.
Reddy GV, Ravindra Babu P, Komaraiah P, Roy KRRM, IL. Kothari Utilization of banana waste for the production of lignolytic and cellulolytic enzymes by solid substrate fermentation using two Pleurotus species (P. ostreatus and P. sajor-caju). Process Biochem. 2003; 38:1457-1462.
Couto SR, Sanrom n M . Effect of two wastes from groundnut processing on laccase production and dye decolourisation ability. J Food Engg. 2006; 73:388-393.
Winquist E, Moilanen U, Mettälä A, Leisola M, Annele Hatakka A. Production of lignin modifying enzymes on industrial waste material by solid-state cultivation of fungi. Biochem Engg J. 2008; 42:128-132.
Sathishkumar P, Murugesan K, Palvannan T. Production of laccase from Pleurotus florida using using agro-wastes and efficient decolorization of
Reactive blue 198. J Basic Microbiol. 2010; 50(4):360-367.
Gassara F, Brar SK, Tyagi RD, John RP, Verma M, Valero JR. Parameter optimization for production of ligninolytic enzymes using agro-industrial wastes by response surface method. Biotechnol Bioprocess Engg. 2011; 16(2):343-351.
Kittikun AH, Kaewthong W, Cheirsilp B. Continuous production of monoacylglycerols from palm olein in packed bed reactor with immobilized lipase PS. Biochem Engg J. 2008; 40:116-120.
Alkan H, Baysal Z, Uyar F, Dogru M. Production of lipase by a newly isolated Bacillus coagulans under solid state fermentation using melon waste. Appl Biochem Biotechnol. 2007; 136:183-192.
Aravindan R, Anbumathi P, Viruthagiri T. Lipase applications in food industry. Indian J Biotechnol. 2007; 6:141-158.
Gutarra MLE, Cavalcanti EDC, Castilho LR, Freire DMG, Anna Jr. GLS. Lipase production by solid-state fermentation cultivation conditions and operation of tray and packed-bed bioreactors. Appl Biochem Biotechnol. 2005; 121-124:105-116.
Mala JG, Edwinoliver NG, Kamini NR, Puvanakrishnan R. Mixed substrate solid state fermentation for production and extraction of lipase from Aspergillus niger MTCC 2594. J Gen Appl Microbiol. 2007; 53:247–253.
Edwinoliver NG, Thirunavukarasu K, Naidu RB, Gowthaman MK, Kambe TN, Kamini NR. Scale up of a novel tri-substrate fermentation for enhanced production of Aspergillus niger lipase for tallow hydrolysis. Bioresour Technol. 2010; 101:6791–6796.
Rajan A, Nair AJ. A comparative study on alkaline lipase production by a newly isolated Aspergillus fumigatus MTCC 9657 in submerged and solid-state fermentation using economically and industrially feasible substrate. Turkish J Biol. 2011; 35:569-574.
Coradi, GV, da Visitação VL, de Lima EA, Saito LYT, Palmieri DA, Takita MA, de Oliva Neto P, de Lima VMG. Comparing submerged and solid-state fermentation of agro-industrial residues for the production and characterization of lipase by Trichoderma harzianum. Ann Microbiol. 2012; 63(2): 533-540.
Oliveira BH, Coradi GV, Attili-Angelis D, Scauri C, Luques AHPG, Barbosa AM, Dekker RFH, Neto PO, Lima VMG. Comparison of lipase production on crambe oil and meal by Fusarium sp. (Gibberella fujikuroi complex). Eur J Lipid Sci Technol. 2013; 115:1413-1425.
Rajendran A, Thangavelu V. Utilizing agricultural wastes as substrates for lipase production by Candida rugosa NCIM 3462 in solid-state fermentation: response surface optimization of fermentation parameters. Waste Biomass Valor. 2013; 4:347–357.
Faisal PA, Hareesh ES, Priji P, Unni KN, Sajith S, Sreedevi S, Josh MS, Benjamin S. Optimization of parameters for the production of lipase from Pseudomonas sp. BUP6 by solid state fermentation. Advances Enzyme Res. 2014; 2:125-133.
Silveira EA, Tardioli PW, Farinas CS. Valorization of palm oil industrial waste as feedstock for lipase
production. Appl Biochem Biotechnol. 2016; doi 10.1007/s12010-016-2013-z.
Daniel EM, Ratnayake S, Kinstle T, Stoner GD. The effect of pH and rat intestinal content on the liberation of ellagic acid from purified and crude ellagitannins. J Nat Prod. 1991; 54:946-952.
Aguilar CN, Gutiérrez-Sanches G. Review: sources, properties, applications and potential uses of tannin acyl hydrolase. Food Sci Tech Int. 2001; 7: 373-382.
Iibuchi, S., Minoda, Y. and Yamada, K. Studies on tannin acyl hydrolase of microorganisms. Part III. Purification of the enzyme and some properties of it. Agric Biol Chem. 1968; 32:803-809.
Deschamps A, Otuk G, Lebeault J. Production of tannase and degradation of chestnut tannin by bacteria. J Ferment Technol. 1983; 61:55-59.
Aoki K, Shinke R, Nishira H. Purification and some properties of yeast tannase. Agri Biol Chem. 1976a; 40:79-85.
De Lima JS, Cruz R, Fonseca JC, Medeiros EV, Maciel MHC, Moreira KA, de Souza Motta CM. Production, characterization of tannase from Penicillium montanense URM 6286 under SSF using agroindustrial wastes, and application in the clarification of grape juice (Vitis vinifera L.). SciWorld J 2014; 2014:1-9.
Rodrigues THS, Pinto GAS, Gonçalves LRB. Effects of inoculum concentration, temperature, and carbon sources on tannase production during solid state fermentation of cashew apple bagasse. Biotechnol Bioprocess Eng. 2008; 13:571-576.
Paranthaman R, Vidyalakshmi R, Singaravadivel K. Comparative study on the suitability of different substrates for tannin acyl hydrolase production using Aspergillus oryzae. J Pharm Sci Res. 2009; 1(4):36-42.
Prasad D, Gupta RK, Venkataratnam GS, Kamini NR, Gowthaman MK. Utilization of bahera fruits for production of tannase and gallic acid by Aspergillus heteromorphus MTCC 5466 and synthesis of propyl gallate thereof. Global J Biotechnol Biochem. 2011; 6(3):119-128.
Mohan SK, Viruthagiri T, Arunkumar C. Statistical optimization of process parameters for the production of tannase by Aspergillus flavus under submerged fermentation. Biotech. 2014; 4(2): 159-166.
Bhoite RN, Murthy PS. Biodegradation of coffee pulp tannin by Penicillium verrucosum for production of tannase, statistical optimization and its application. Food Bioprod Process. 2015; 94:727-735.
Malgireddy NR, Nimma LNR. Optimal conditions for production of tannase from newly isolated Aspergillus terrus under solid state fermentation. Eur J Biotechnol Biosci 2015; 3(2):56-64.
Amin F, Bhatti HN, Asgher M. Partial purification and characterization of an acid invertase from Saccharum officinarum L. Pak J Bot. 2010; 42(4):2531-2540.
Bagal DS, Vijayan A, Aiyer RC, Karekar RN, Karve MS. Fabrication of sucrose biosensor based on single mode planar optical wave guide using
coimmobilized plant invertase and GOD. Biosens Bioelectron. 2007; 22: 3072-3079.
Kotwal SM, Shankar V. Immobilized invertase. Biotechnol Adv. 2009; 27:311-322.
Mase T, Hirose E, Shimizu K, Uchikawa E. Isolation, characterization and application of invertase from Pseudozyma sp 1-8. Sugiyama Jogakuen University Research Journal: Humanities, Social Science and natural science Hen. 2009; 40:147-156.
Ul-Haq I, Ali S. Invertase production from a hyper producing Saccharomyces cerevisiae strain isolated from dates. Pak J Bot. 2005; 37(3):749-759.
Rashid MM, Nooman MU. Production and partial characterization of invertase from Saccharomyces cerevisiae NRRL Y-12632 by Solid-State fermentation of red carrot Residue. Australian J Basic Appl Sci. 2009; 3(3):1910-1919.
Uma C, Gomathi D, Muthulakshmi C, Gopalakrishnan VK. Production, purification and characterization of invertase by Aspergillus flavus using fruit peel waste as substrate. Adv Biol Res. 2010; 4(1):31-36.
Kumar R, Kesavapillai B. Stimulation of extracellular invertase production from spent yeast when sugarcane pressmud used as substrate through solid state fermentation. SpringerPlus. 2012, 1:1-6.
Ashraf H, Bilal ZH. Biosynthesis, partial purification and characterization of invertase through carrot (Daucus carota l.) peels. J Biochem Tech. 2015; 6(1):867-874.
Ahmed K, Munawar S, Khan MA. Beta-D-fructofuranosidase production by Aspergillus niger IBGE 01 using shaken flask technique of submerged fermentation. Pure Appl Biol. 2015; 4(3): 323-330.
Gupta R, Beg QK, Lorenz P. Bacterial alkaline protease: molecular approaches and industrial applications. Appl Microbiol Biotechnol. 2002; 59:15-32.
Rao MB, Aparna M, Tanksale M, Ghatge S, Deshpande VV. Molecular and biotechnological aspects of microbial proteases. Microbiol Mol Biol Rev. 1998; 62:597-635.
Kumar CG, Tiwari MP, Jany KD. Novel alkaline serine protease from alkalophilic Bacillus spp: Purification and some properties. Process Biochem. 1999; 34: 441-449.
Mabrouk SS, Hashem AM, El-Shayeb NMA, Ismail AMS, Abdel-Fattah AF. Optimization of alkaline protease productivity by Bacillus licheniformis ATCC 21415. Bioresour Technol. 1999; 69:155-159.
Johnvesly B, Manjunath BR, Naik GR. Pigeon pea waste as a novel, inexpensive, substrate for production of a thermostable alkaline protease from thermoalkalophilic Bacillus sp. JB-99. Bioresour Technol. 2002; 82:61-64.
Prakasham RS, Rao CS, Rao RS, Sarma PN. Alkaline protease production by an isolated Bacillus circulans under solid-state fermentation using agro industrial waste: Process parameters optimization. Biotechnol Prog. 2005; 21:1380-1388.
Prakasham RS, Rao CS, Sarma PN. Green gram husk-an inexpensive substrate for alkaline protease
production by Bacillus sp. in solid state fermentation. Bioresour Technol. 2006; 97:1449-1454.
Mukherjee AK, Adhikari H, Rai SK. Production of alkaline protease by a thermophilic Bacillus subtilis under solid state fermentation (SSF) condition using Imperata cylindrica grass and potato peel as low cost medium: Characterization and application of enzyme in detergent formulation. Biochem Eng J. 2008; 39:353-361.
Madhuri A, Nagaraju B, Harikrishna N, Reddy G. Production of alkaline protease by Bacillus altitudinis GVC11 using castor husk in solid state fermentation. Appl Biochem Biotechnol. 2012; 167:1199-1207.
Meena P, Tripathi AD, Srivastava SK, Jha A. Utilization of agro-industrial waste (wheat bran) for alkaline protease production by Pseudomonas aeruginosa in SSF using taguchi (DOE) methodology. Biocatal Agric Biotech. 2013; 210-216
Desmukh RR, Vidhale NN. Utilization of agro industrial waste for production of protease by Fusarium oxysporum in solid state fermentation. Indian J Appl Res. 2015; 5(7): 611-612.
Singh S, Bajaj BK. Bioprocess optimization for production of thermoalkali-stable protease from Bacillus subtilis K-1 under solid state fermentation. Prep Biochem Biotechnol. 2016.
Elinbaum S, Ferreyra H, Ellenrieder GC. Production of Aspergillus terreus L-rhamnosidase by solid state fermentation. Lett Appl Microbiol. 2002; 34: 67-71.
Roitner M, Schalkhammer T, Pittner F. Preparation of prunin with the help of immobilized naringinase pretreated with alkaline buffer. Appl Biochem Biotechnol. 1984; 9(5-6):483-488.
Puri M, Banerjee UC. Production, purification and characterization of debitttering enzyme naringinase. Biotechnol Adv. 2000; 18: 207-217.
Terada Y, Kometani T, Nishimura T, Takii H, Okada S. Prevention of hesperidin crystal formation in canned mandarin orange syrup and clarified orange juice by hesperidin glycosides. Food Sci Technol Int. 1995; 1(1):29-33.
Caldini C, Bonomi F, Pifferi PG, Lanzarini G, Galante YM. Kinetic and immobilization studies on fungal glycosidases for aroma enhancement in wine. Enzym Microb Tech. 1994; 16(4): 286-291.
Stredansky M, Conti E , Navarini L, Bertocchi C. Production of bacterial exopolysaccharides by solid substrate fermentation. Process Biochem. 1999; 34(1):11-16.
Cal AM, Glory LC, Lizama-Uc G, Ortiz-Vázquez E. Naringinase production from filamentous fungi using grapefruit rind in solid state fermentation. Afr J Microbiol Res. 2010; 4(19):1964-1969.
Shanmugaprakash M, Kumar VV, Hemalatha M, Melbia V, Karthik P. Solid-state fermentation for the production of debittering enzyme naringinase using Aspergillus niger MTCC 1344. Eng Life Sci. 2011; 11(3):322-325.
Petri AC, Buzato JB, Celligoi MAPC, Borsato D. Optimization of the production of α-L- rhamnosidase by aspergillus niger in solid state fermentation using
agro-industrial residues. Br Microbiol Res J. 2014; 4(11):1198-1210.
Shehata AN, El Aty AAA. Optimization of process parameters by statistical experimental designs for the production of naringinase enzyme by marine fungi. Int J Chem Eng. 2014; 2014:1-10.
Panesar PS, Panesar R, Singh RS, Kennedy JF, Kumar H. Microbial production, immobilization and applications of β-D-galactosidase. J Chem Technol Biotechnol. 2006; 81:530-543
Vasiljevic T, Jelen P. Production of β-galactosidase for lactose hydrolysis in milk and dairy products using thermophilic lactic acid bacteria. Innov Food Sci Emerg Technol. 2001; 2:75-85.
Panesar PS. Production of -D-galactosidase from whey using Kluyveromyces marxianus. Research J Microbiol. 2008; 3:24-29.
De Bales SA, Castillo FJ. Production of lactase by Candida pseudotropicalis grown in whey. Appl Environ Microbiol. 1979; 37:1201-1205.
El-Gindy A, Ibrahim Z, Aziz H. Improvement of extracellular β-galactosidase production by thermophilic fungi Chaetomium thermophile and Thermomyces lanuginosus. Australian J Basic Appl Sci. 2009; 3(3):1925-1932.
Bansal S, Oberoi, HS, Dhillon GS Patil RT. Production of β-galactosidase by Kluyveromyces marxianus MTCC 1388 using whey and effect of four different methods of enzyme extraction on β-galactosidase activity. Indian J. Microbiol. 2008;.48:337-341.
Gupte AM, Nair JS. β-galactosidase production and ethanol fermentation from whey using Kluyveromyces marxianus NCIM 3551. J Sci Ind Res. 2008; 69:855-859.
Murad HA, Refaea RI, Aly EM. Utilization of UF-permeate for production of β-galactosidase by lactic acid bacteria. Polish J Microbiol. 2011; 60:139-144.
Princely S, Basha NS, Kirubakaran JJ, Dhanaraju MD. Biochemical characterization, partial purification, and production of an intracellular beta galactosidase from Streptococcus thermophilus grown in whey. Eur J Expt Biol. 2013; 3(2):242-251.
Prasad LN, Ghosh BC, Sherkat F, Shah NP. Extraction and characterisation of β-galactosidase produced by Bifidobacterium animalis spp. lactis Bb12 and Lactobacillus delbrueckii spp. bulgaricus ATCC 11842 grown in whey. Int Food Res J. 2013; 20:487-494.
Braga ARC, Gomes PA, Kalil SJ. Formulation of culture medium with agro-industrial waste for β-galactosidase production from Kluyveromyces marxianus ATCC 16045. Food Bioprocess Technol. 2012; 5:1653-1663.
Perini BLB, Souza HCM, Kelbert M, Apati GP. Production of β-galactosidase from cheese whey using Kluyveromyces marxianus CBS 6556. Chem Eng Transactions. 2013; 32:991-996.
Miradamadi S, Moazami N, Gorgani MN. Production of β-galactosidase in submerged media by Aspergillus oryzae. PTCC 5163. J Sci Islamic Repub Iran. 1997; 8:23–27.
de Vries RP, Visser J. Aspergillus enzymes involved in degradation of plant cell wall polysaccharides. Microbiol Mol Biol Rev.2001; 65:497-522.
Nizamuddin S, Sridevi A, Narasimha G. Production of β-galactosidase by Aspergillus oryzae in solid-state fermentation. Afr J Biotechnol. 2008; 7(8):1096-1100.
Raol GG, Raol BV, Prajapati VS. Utilization of agro-industrial waste for β-galactosidase production under solid state fermentation using halotolerant Aspergillus tubingensis GR1 isolate. Biotech. 2015; 5(4): 411-421.
Antoine AA, Bedikou ME, Anastasie SYA, Sebastien NL, Jacqueline D, Philippe T. β-galactosidase production by solid state fermentation of wheat bran/whole wheat without any supplement. World J Pharm Pharma Sci. 2015; 4(8):196-207.
Bhalla TC, Chatanta DK. Application of enzymes in food processing, In: Marwaha SS, Arora JK, Food processing: Biotechnological Applications. Asiatech Publishers Inc., New Delhi, 2000; pp. 123-142.