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Vol. 2 No. 4 (2016)

April 2017

Spinal location of lymphoma tumor as an uncommon first manifestation of AIDS; A case report

  • Maryam Ansari Chaharsoughi
  • Farzin Khorvash
  • Mohammad Reza Yazdani

Social Determinants of Health, Vol. 2 No. 4 (2016), 16 April 2017 , Page 162-165
https://doi.org/10.22037/sdh.v2i4.20909 Published: 2016-10-23

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Abstract

Abstract:

Introduction: Patients struggling with acquired immune deficiency syndrome (AIDS) are significantly at higher risk of developing lymphoma. Lymphoma usually occurs in uncommon extra-nodal sites in immune deficient patients. In current study we have aimed to introduce a case with spinal Burkitt's lymphoma (BL) as the first manifestation of HIV.

Case presentation: A 36-year-old drug addicted, married male was free of drug abuse since 10 years ago, referred to Al-Zahra Hospital with complaint of back pain that radiated to lower limb. Intervertebral disk protrusion at L5-S1 level and paravertebral abscess at T10-T11 levels were found in MRI. Due to history of IV-drug using, HIV tests were sent for him and viral load was 52107 copies/ml and genotype indicated infection of HIV-1. Number of CD-4+ cells was checked as well. The number equaled 24. After necessary consultants, he underwent decompressive laminectomy and fixation and sample biopsy in order of infection/neoplasm ruling-out was sent. Results of biopsy showed histological and immunohistochemical findings in favor of burkiit's lymphoma.

Conclusion: BL can be the first manifestation of HIV that uncommon site of it can act as a clue to early diagnosis of HIV/AIDS.

Key words: AIDS, HIV, Lymphoma, Burkitt's lymphoma, back pain

 

Keywords:
  • AIDS
  • HIV
  • Lymphoma
  • Burkitt's lymphoma
  • back pain
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How to Cite

Ansari Chaharsoughi, M., Khorvash, F., & Yazdani, M. R. (2016). Spinal location of lymphoma tumor as an uncommon first manifestation of AIDS; A case report. Social Determinants of Health, 2(4), 162–165. https://doi.org/10.22037/sdh.v2i4.20909
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References

-Tirelli U, Spina M, Gaidano G, Vaccher E, Franceschi S, Carbone A. Epidemiological, biological and clinical features of HIV-related lymphomas in the era of highly active antiretroviral therapy. Aids. 2000;14(12):1675-88.

.2-Molyneux EM, Rochford R, Griffin B, Newton R, Jackson G, Menon G, et al. Burkitt's lymphoma. The Lancet. 2012;379(9822):1234-44.

.3-Blum KA, Lozanski G, Byrd JC. Adult Burkitt leukemia and lymphoma. Blood. 2004;104(10):3009-20.

.4-Cabrera M, Silva G, Soto A, Rosello R, Castro C, Martinez V, et al. HIV-related lymphoma in a public hospital in Chile. Analysis of 55 cases. Revista medica de Chile. 2012;140(2):243-50.

Mascarenhas JG, Araújo Júnior F, Bolzan TV, Gregórioa LC, Kosugi EM. Nasopharyngeal Burkitt lymphoma as an early AIDS manifestation. Brazilian journal of otorhinolaryngology. 2014;80(6):546-8.

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

 

 

 

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