Microsurgery for Subclinical Varicocele: Does the Evidence Support Intervention?
Archives of Men's Health,
卷 8 编号 1 (2024),
31 七月 2024
,
第 e10 页
https://doi.org/10.22037/amh.v8i1.49202
摘要
Subclinical Varicocele (SV) remains one of the most controversial entities in male infertility management. Although major guidelines do not recommend treatment, growing evidence suggests that microsurgical repair may benefit selected patients. This review critically examines current guidelines, available clinical evidence, potential mechanisms of damage, and patient selection strategies. Emerging
biomarkers and personalized approaches may help redefine management. While routine surgery for SV is not justified, individualized decision-making may bridge the gap between evidence and clinical need [1,2].
- Microsurgery
- Paternity
- Semen Analysis
- Varicocele
- Ultrasonography
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参考
Brannigan RE, Hermanson L, Kaczmarek J, Kim SK, Kirkby E, Tanrikut C. Updates to male infertility: AUA/ASRM guideline (2024). Journal of Urology. 2024 Jan 15:10-97.
Catto J. European Association of Urology Guidelines on Male Sexual and Reproductive Health: 2021 Update on Male Infertility.
Sountoulides P, Pyrgidis N, Kaltsas A, Gravas S, Kikidakis D, Zachos I, Zachariou A, Dimitriadis F, Sofikitis N, Kikidakis DS. Comparative Impact of Microsurgical Varicocelectomy Versus Observation on Infertility in Infertile Men with Subclinical Varicocele. Cureus. 2025 Jan 15;17(1).
Thirumavalavan N, Scovell JM, Balasubramanian A, Kohn TP, Ji B, Hasan A, Pastuszak AW, Lipshultz LI. The impact of microsurgical repair of subclinical and clinical varicoceles on total motile sperm count: is there a difference? Urology. 2018 Oct 1; 120:109-13.
Kim HJ, Seo JT, Kim KJ, Ahn H, Jeong JY, Kim JH, Song SH, Jung JH. Clinical significance of subclinical varicocelectomy in male infertility: Systematic review and meta‐analysis. Andrologia. 2016 Aug;48(6):654-61.
Agarwal A, Sharma RK, Desai NR, Prabakaran S, Tavares A, Sabanegh E. Role of oxidative stress in pathogenesis of varicocele and infertility. Urology. 2009 Mar 1;73(3):461-9.
Wood GJ, Cardoso JP, Paluello DV, Nunes TF, Cocuzza M. Varicocele-associated infertility and the role of oxidative stress on sperm DNA fragmentation. Frontiers in Reproductive Health. 2021 Oct 29;3:695992.
Mehta A, Goldstein M. Microsurgical varicocelectomy: a review. Asian Journal of Andrology. 2012 Nov 12;15(1):56.
Ma Y, Zhou Y, Xiao Q, Zou SS, Zhu YC, Ping P, Chen XF. Seminal exosomal miR‐210‐3p as a potential marker of Sertoli cell damage in Varicocele. Andrology. 2021 Jan;9(1):451-9.
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