Tyrosinase Inhibitory Activity of Selected Plants Based on Iranian Traditional Medicine Detection of mushroom tyrosinase inhibitors based on ITM
International Pharmacy Acta,
Vol. 5 No. 1 (2022),
19 June 2022
,
Page e4: 1-5
https://doi.org/10.22037/ipa.v5i1.38023
Abstract
Discovery of safe and stable skin whitening agents for medical and cosmetic purposes has drawn attention in recent years. For the same reason, this study was undertaken to evaluate tyrosinase inhibitory activity of some medicinal plants introduced in Iranian Traditional Medicine as hypopigmenting agents. In recent research, tyrosinase inhibitory effect and antioxidant activity of selected plants were evaluated using mushroom tyrosinase inhibitory assay and DPPH radical scavenging test and, in addition, total phenol content of extracts was measured. Out of nine aqueous extracts of selected plants, the effect of Ricinus communis L. and Nepeta glomerulosa Boiss. on tyrosinase inhibition was significant with 71.99 and 89.98 percent inhibition, respectively. Moreover, Pistacia atlantica L. showed the highest total phenol content with the most potent DPPH radical scavenging effect and high anti-tyrosinase activity with 59.07 percent of inhibition. The obtained results suggest that Ricinus communis, Nepeta glomerulosa and Pistacia atlantica could be good candidates for further investigation to find novel agents for skin hyperpigmentation.
- Antioxidant activity
- Nepeta glomerulosa
- Pistacia atlantica
- Ricinus communis
- Mushroom tyrosinase inhibitors
How to Cite
References
Yamaguchi y, Brenner M, Hearing VJ. The Regulation of Skin Pigmentation. J Biol Chem. 2007; 282(38):7557-77561.
Acton A. Sugar Acids—Advances in Research and Application. Scholarly edition. Atlanta, Georgia; 2013.
Kim SS, Kim MJ, Choi YH, Kim BK, Kim KS, Park KJ, et al. Down-regulation of tyrosinase, TRP-1, TRP-2 and MITF expressions by citrus press-cakes in murine B16 F10 melanoma. Asian Pac. J Trop Biomed. 2013; 3(8):617–622.
Agar N, Young AR. Melanogenesis: a photoprotective response to DNA damage? Mutat Res. 2005; 571(1-2):121-132.
Chang TS. An Updated Review of tyrosinase Inhibitors. Int J Mol Sci. 2009; 10(6):2440–2475.
Loizzo MR, Tundis R, Menichini F. Natural and Synthetic Tyrosinase Inhibitors as Anti-browning Agents: An Update. Compr Rev Food Sci Food Saf. 2012; 11(4):378.
Kim M, Park J, Song K, Kim HG, Koh JS, Boo YC. Screening of plant extracts for human tyrosinase inhibiting effects. Int J Cosmet Sci. 2012; 34(2):202–208.
Parvez S, Kang M, Chung HS, Bae H. Naturally occurring tyrosinase inhibitors: mechanism and applications in skin health, cosmetics and agriculture industries. Phytother Res. 2007; 21(9):805-816.
Lee SY, Baek N, Nam TG. Natural, semisynthetic and synthetic tyrosinase inhibitors. J Enzyme Inhib Med Chem. 2016; 31(1):1-13.
El-kady IA, Zohri AA, Ragab SH. Kojic Acid Production from Agro-Industrial By-Products Using Fungi. Biotechnol Res int. (2014; 1-10.
Mata TL, Sanchez JP, de la Cuadra Oyanguren J. Allergic contact dermatitis due to kojic acid. Dermatitis. 2005; 16(2):89.
Draelos ZD. Skin lightening preparations and the hydroquinone controversy. Dermatol ther. 2007; 20(5):308–313.
Sahranavard S, Khoramjouy M, Khakpash M, Askari SA, Faizi M, Mosaddegh M. Hydroethanolic extract of Lavandula angustifolia ameliorates vincristine-induced peripheral neuropathy in rats. Res Pharm Sci. 2022 Apr 18; 17(3):265-273.
Bahaeddin Z, Yans A, Khodagholi F, Sahranavard S. Dietary supplementation with Allium hirtifolium and/or Astragalus hamosus improved memory and reduced neuro-inflammation in the rat model of Alzheimer’s disease. Applied Physiol. Nutr Metab. 2017; 43(6):558-564.
Ranjbar Ekbatan M, Khoramjouy M, Gholamine B, Faizi M, Sahranavard S. Evaluation of Anticonvulsant Effect of Aqueous and Methanolic Extracts of Seven Inula Species. Iran J Pharm Res. 2019 Fall; 18(Suppl1):208-220.
Ghafari S, Fahimi Sh, Sahranavard S. Plants used to treat hyperpigmentation in Iranian traditional medicine: a review. Res J Pharmacogn. 2017; 4(4):71-85.
Zakerin S, Fahimi S, Rezghi M. Anti-Freckles Herbal Treatment in Iranian Traditional Medicine. Iran J Med Sci. 2016 May; 41(3 Suppl):22.
Pourmand M, Asgharzadeh M, Rashedi J, Mahdavi Poor B. Vitiligo Treatment in Ancient Iranian Medicine. Iran J Public Health. 2016 Aug; 45(8):1100-1101.
Zhang QW, Lin LG, Ye WC. Techniques for extraction and isolation of natural products: a comprehensive review. Chin Med. 2018 Apr 17; 13:20.
Sarkhail P,Salimi M, Sarkheil P, Heidarnezhad F, Saeidnia S. Evaluation of anti-melanogenic and cytotoxic activities of Phlomis caucasica on human melanoma SKMEL-3 cells. Int J Cancer Manag. 2017; 10(3):4.
Nerya O, J Vaya J, Musa R, Izrael S, Ben-Arie R, Tamir S. Glabrene and Isoliquiritigenin as Tyrosinase Inhibitors from Licorice Roots. J Agr Food Chem. 2003; 51(5):1201-1207.
Alobaidi AH, Hamad ES, Alsamarai AM, Kudair KA. Evaluation of Glycyrrhiza glabra Cream as Treatmentfor Melasma. In: Badria, F. A. editor. Evidence-based Strategies in Herbal Medicine, Psychiatric Disorders and Emergency Medicine [Internet]. London: IntechOpen; 2015
Tengamnuay P, Pengrungruangwong K, Pheansri I, Likhitwitayawuid K. Artocarpus lakoocha heartwood extract as a novel cosmetic ingredient: evaluation of the in vitro anti-tyrosinase and in vivo skin whitening activities. Int J Cosmet Sci. 2006 Aug; 28(4):269-76.
Fukumoto LR, Mazza G. Assessing antioxidant and prooxidant activities of phenolic compounds. J Agr Food Chem. 2000; 8(8):3597-604.
Al-Duais M, Müller L, Böhm V, Jetschke G. Antioxidant capacity and total phenolics of Cyphostemma digitatum before and after processing: use of different assays. Eur Food Res Technol. 2009; 228(5):813–821.
Noor SU, Faridah F, M Michico. Formulation of liquorice root extract (Glycyrrhiza glabra L.) as skin whitening cream. indonesian J of Plant med. 2016 ;9(2):93-99.
Adhikari A, Devkota HPA, Takano K, Masuda T, Nakane P. Basnet, N. Skalko-Basnet. Screening of Nepalese crude drugs traditionally used to treat hyperpigmentation: in vitro tyrosinase inhibition. Int J Cosmet Sci. 2008; 30:353–360.
Radhakrishnan N, Phil M, Gnanamani A, Sadulla S. Effect of Licorice (Glycyrriza glabra L.), a Skin-whitening agent Datura alba on Black Molly (Poecilia latipinnaa). J Appl Cosm. 2005; 23:149–158.
Nemudzivhadi V, Masoko P. In vitro Assessment of Cytotoxicity, Antioxidant, and Anti-Inflammatory Activities of Ricinus communis (Euphorbiaceae) Leaf Extracts. Evid Based Complement Altern Med. 2014; 1-9.
Elnour MA, Elegamy AA, Koko WS, Khalid A, Fadul E. Antioxidant Activity and Cytotoxicity of some Sudanese Medicinal Plants. Inter J Adv Indust Eng. 2013; 1:20–3.
Iqbal J, Zaib S, Farooq U, Khan A, Bibi I, Suleman S. Antioxidant, Antimicrobial, and free radical scavenging potential of aerial parts of Periploca aphylla and Ricinus communis. Pharmacol. 2012; 1-6.
Emami SA, Yazdian-Robati R, Arab A, Sadeghi M, Tayarani-Najaran Z. Anti-Melanogenic activity of different extracts from aerial parts of Nepeta glomerulosa on murine melanoma B16F10 cells. Iran J Pharm Res. 2017; 13(2):61-74.
Akaberia M, Emami S.A, Vatania M, Tayarani-Najaranc Z. Evaluation of antioxidant and anti-melanogenic activity of different extracts of aerial parts of N. Sintenisii in murine melanoma B16F10 cells. Iran J Pharm Res. 2018; 17(1):225-235.
Tayarani-Najaran Z, Akaberi M, Vatani M and Emami SA. Evaluation of antioxidant and anti-melanogenic activities of different extracts from aerial parts of Nepeta binaludensis Jamzad in murine melanoma B16F10 cells. Iran J Basic Med Sci. 2016 19(6):662-669.
Emami SA, Yazdian-Robati R , Sadeghi M, Baharara J , Amini E , Salek F and Tayarani-Najaran Z. Res Pharma Sci. 2017; 12(2):160-167.
Edrah S, Alafid F , Kumar A. Preliminary Phytochemical Screening and Antibacterial Activity of Pistacia atlantica and Prunus persica Plants of Libyan Origin. Int J Sci Res. 2015; 4(2):1552-1555.
Peksel A. Antioxidative properties of decoction of Pistacia atlantica Desf. Leaves. Asian J Chem. 2008; 20(1):681-693.
Bozorgi M, Memariani Z, Mobli M, Salehi Surmaghi MH, Shams-Ardekani MR, Rahimi R. Five Pistacia species (P. vera, P. atlantica, P. terebinthus, P. khinjuk, and P. lentiscus): A Review of Their Traditional Uses. Phytochem. Pharmacol. Sci. World J. 2013; 1-33
Alam N. Yoon KN, Lee JS, Cho HJ, Lee TS. Consequence of the antioxidant activities and tyrosinase inhibitory effects of various extracts from the fruiting bodies of Pleurotus ferulae. Saudi J Biol Sci. (2012; 19(1):111-118.
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