Risk of Outbreak Omicron Virus by Increasing the Number of Mutations in the Receptor Binding Domain (RBD) Increasing number of mutations in RBD in Omicron outbreak

Trends in Peptide and Protein Sciences, Vol. 7 (2022), 7 March 2022 , Page 1-3 (e1)
https://doi.org/10.22037/tpps.v7i.37447

Abstract

HIGHLIGHTS

  • Rapid spread of Omicron variant is a serious challenge.
  • More than 50 mutations have occurred in Omicron variant.
  • The mutations have caused the RBD structure to undergo significant changes
Keywords:
  • Mutation
  • Omicron
  • Receptor binding domain (RBD)
  • Spike protein

How to Cite

1.
Pooladi M, Karani S. Risk of Outbreak Omicron Virus by Increasing the Number of Mutations in the Receptor Binding Domain (RBD): Increasing number of mutations in RBD in Omicron outbreak. Trends Pept. Protein Sci. [Internet]. 2022 Mar. 7 [cited 2025 Mar. 23];7:1-3 (e1). Available from: https://journals.sbmu.ac.ir/protein/article/view/37447

References

Cohen, J. (2021). ″Omicron sparks a vaccine strategy debate.″ Science, 374(6575):1561-1562. DOI: 10.1126/science.acz9879.

Cross, R. (2021). ″Omicron puts scientists on red alert.″ C&EN Global Enterprise, 99 (44): 6-6. DOI: 10.1021/cen-09944-leadcon.

Graham, F. (2021). ″Daily briefing: Omicron might weaken vaccine protection.″ Nature Briefing. DOI: 10.1038/d41586-021-03689-8.

Hastie, K.M., Li, H., Bedinger, D., Schendel, S.L., Dennison, S.M., Li, K. and E.O. Saphire, (2021). ″Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study.″ Science, 374(6566): 472-478. DOI: 10.1126/science.abh2315.

Karim, S.S.A. and Q.A. Karim, (2021). ″Omicron SARS-CoV-2 variant: A new chapter in the COVID-19 pandemic.″ The Lancet, 398(10317): 2126-2128. DOI: 10.1016/S0140-6736(21)02758-6.

Kim, S., Nguyen, T. T., Taitt, A. S., Jhun, H., Park, H. Y., Kim, S. H. and S. Kim, (2021). ″SARS-CoV-2 Omicron mutation is faster than the chase: Multiple mutations on Spike/ACE2 interaction residues.″ Immune Network, 21(6): e38. DOI: 10.4110/in.2021.21.e38.

Kumar, S., Thambiraja, T.S., Karuppanan, K. and G. Subramaniam, (2021). ″Omicron and Delta variant of SARS‐CoV‐2: A comparative computational study of spike protein.″ Journal of Medical Virology, 2021: 1–9. DOI: 10.1002/jmv.27526.

Li, A., Maier, A., Carter, M. and T Hugh Guan, (2021). ″Omicron and S‐gene target failure cases in the highest COVID‐19 case rate region in Canada - December 2021.″ Journal of Medical Virology. 2022:1-3. DOI: 10.1002/jmv.27562.

Meo, S.A., Meo, A.S., Al-Jassir, F.F. and D.C. Klonoff, (2021). ″Omicron SARS-CoV-2 new variant: global prevalence and biological and clinical characteristics. European Review for Medical and Pharmacological Sciences, 25(24): 8012-8018. DOI: 10.26355/eurrev_202112_27652.

Pooladi, M., Entezari, M., Hashemi, M., Bahonar, A., Hushmandi, K. and M. Raei, (2020). Investigating the efficient management of different countries in the COVID-19 pandemic.″ Journal of Marine Medicine, 2(1):18-25. DOI :10.30491/2.1.3.

Pooladi, M., Hushmandi, K. and M. Entezari, (2021). ″Risk of increased expression of ACE2 membrane protein in patients with hypertension: Review of COVID-19.″ Archives of Advances in Biosciences, 12(1): 52-64. DOI.org/10.22037/aab.v12i1.30521.

Rath, S.L., Padhi, A.K. and N. Mandal, (2022). ″Scanning the RBD-ACE2 molecular interactions in Omicron variant.″ Biochemical and Biophysical Research Communications, 592:18-23. DOI: 10.1016/j.bbrc.2022.01.006.

Sharma, S.R. (2021). ″Omicron sets alarm bells ringing.″ Homoeopathic Links, 34(04): 255-256. DOI: 10.1055/s-0041-1741016.

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