Antibiotic Prophylaxis Prescription in Simple Traumatic Wounds Treated in Emergency Department
Iranian Journal of Emergency Medicine,
Vol. 4 No. 4 (2017),
8 October 2017
,
Page 173-169
https://doi.org/10.22037/ijem.v2i1.17212
Abstract
Introduction: Currently, considering the advances made in management of traumatic wounds, preventing secondary infections following these accidents is considered a serious challenge. Although using antibiotics for prophylaxis to reduce infection has become less popular, it is still discussed as a method of reducing infection. The aim of the present study is to evaluate the rate and route of antibiotic prophylaxis prescription in traumatic wounds treated in emergency department (ED) and compare it with international standards. Methods: This cross-sectional study was carried out in the ED of Shohadaye-Hafte-Tir Hospital, Tehran, Iran. Patients with simple traumatic wounds were included via easy non-probability method. Before wound healing, the researcher evaluated the patient’s wound regarding appearance, site, cause of injury, length and depth of the wound, time since occurrence of injury, and presence or absence of evident contamination, and determined presence or absence of indication for prescribing antibiotics based on recommendations of approved references in emergency medicine. The researcher asked the patients questions regarding receiving or not receiving antibiotic prophylaxis and its duration after the healing of the wound. Data were analyzed using SPSS-21 after gathering. Results: Overall, 296 patients with the mean age of 31.56 ± 14.74 years were evaluated, 816% of which were male. For 268 (90.5%) of the studied patients, antibiotics was prescribed. However, only 58 (19.6%) had indications for prophylaxis prescription. All of the patients who had indications for receiving antibiotics had received antibiotic prophylaxis. According to the results of this study, antibiotic prophylaxis was prescribed without indications in 210 (71%) of the patients. There was a significant difference (p=0.0001) between the duration of antibiotic prophylaxis prescription in this study and the standard duration recommended for simple wounds. Duration of antibiotics prescription was more than 3 days regarding wounds with evident contamination (p=0.018) and wounds with indication of antibiotic prescription (p=0.007). Sex of the patients, wound type, and anatomic site of injury did not have a significant effect on the mean duration of antibiotics prescription compared to the recommended rate (p > 0.05). Conclusion: Based on the results of the present study, for 71% of the patients with simple traumatic wounds, antibiotic prophylaxis was prescribed without presence of indications and the duration of antibiotic prophylaxis prescription was longer than the standard recommendations.- آنتی بیوتیک پروفیلاکسی؛ بخش اورژانس؛ عفونت زخم
How to Cite
References
Capellan O, Hollander JE. Management of lacerations in the emergency department. Emergency medicine clinics of North America. 2003;21(1):205-31.
Moscati RM, Mayrose J, Reardon RF, Janicke DM, Jehle DV. A multicenter comparison of tap water versus sterile saline for wound irrigation. Academic Emergency Medicine. 2007;14(5):404-9.
Fernandez RS, Griffiths RD, Ussia C. Wound cleansing: which solution, what technique? Primary Intention: The Australian Journal of Wound Management. 2001;9(2):51-8.
Nicks B, Ayello E, Woo K, Nitzki-George D, Sibbald R. Acute wound management: revisiting the approach to assessment, irrigation, and closure considerations. International journal of emergency medicine. 2010;3(4):399-407.
Swanson T, Asimus M, McGuiness B. Wound management for the advanced practitioner: IP Communications; 2014.
Nakamura Y, Daya M. Use of appropriate antimicrobials in wound management. Emergency medicine clinics of North America. 2007;25(1):159-76.
Zehtabchi S, Yadav K, Brothers E, Khan F, Singh S, Wilcoxson RD, et al. Prophylactic antibiotics for simple hand lacerations: time for a clinical trial? Injury. 2012;43(9):1497-501.
Quinn J, McDermott D, Rossi J, Stein J, Kramer N. Randomized controlled trial of prophylactic antibiotics for dog bites with refined cost model. The western journal of emergency medicine. 2010;11(5):435-41.
Singer AJ, Hollander JE. Lacerations and Acute Wounds: An Evidence-Based Guide: FA Davis Company; 2003.
Houshian S, Seyedipour S, Wedderkopp N. Epidemiology of bacterial hand infections. International journal of infectious diseases. 2006;10(4):315-9.
Talan DA, Abrahamian FM, Moran GJ, Citron DM, Tan JO, Goldstein EJ, et al. Clinical presentation and bacteriologic analysis of infected human bites in patients presenting to emergency departments. Clinical Infectious Diseases. 2003;37(11):1481-9.
Cutting K, White R. Defined and refined: criteria for identifying wound infection revisited. British journal of community nursing. 2004;9(3):S6-15.
Hollander J, Singer A, Valentine S, Shofer F. Risk factors for infection in patients with traumatic lacerations. Academic emergency medicine: official journal of the Society for Academic Emergency Medicine. 2001;8(7):716-20.
Perelman VS, Francis GJ, Rutledge T, Foote J, Martino F, Dranitsaris G. Sterile versus nonsterile gloves for repair of uncomplicated lacerations in the emergency department: a randomized controlled trial. Annals of emergency medicine. 2004;43(3):362-70.
Zehtabchi S. The role of antibiotic prophylaxis for prevention of infection in patients with simple hand lacerations. Annals of emergency medicine. 2007;49(5):682-9. e1.
Tintinalli J, Stapczynski J, MA O, Yealy D, Meckler G, Cline D. Tintinalli's emergency medicine: a comprehensive study guide. 8 ed: Mc Graw Hill; 2016.
Brewer JD, Gonzalez AB, Baum CL, Arpey CJ, Roenigk RK, Otley CC, et al. Comparison of sterile vs nonsterile gloves in cutaneous surgery and common outpatient dental procedures: a systematic review and meta-analysis. JAMA dermatology. 2016;152(9):1008-14.
Ghafouri HB, Zare M, Bazrafshan A, Abazarian N, Ramim T. Randomized, controlled trial of povidone-iodine to reduce simple traumatic wound infections in the emergency department. Injury. 2016;47(9):1913-8.
Ghafouri HB, Zavareh M, Jalili F, Cheraghi S. Is 1% povidone-iodine solution superior to normal saline for simple traumatic wound irrigation? Wound Medicine. 2016;15:1-5.
Runde D. Myths in Emergency Medicine: Time to Tap Out? Water or Saline for Wound Irrigation? Emergency Medicine News. 2016;38(7):21-5.
Ghafouri H, Bagheri-Behzad B, Yasinzadeh M, Modirian E, Divsalar D, Farahmand S. Prophylactic Antibiotic Therapy in Contaminated Traumatic Wounds: Two Days versus Five Days Treatment. BioImpacts: BI. 2012;2(1):33-7.
Sirijatuphat R, Choochan T, Siritongtaworn P, Sripojtham V, Thamlikitkul V. Implementation of antibiotic use guidelines for fresh traumatic wound at Siriraj Hospital. Journal of the Medical Association of Thailand= Chotmaihet thangphaet. 2015;98(3):245-52.
Rodriguez L, Jung HS, Goulet JA, Cicalo A, Machado-Aranda DA, Napolitano LM. Evidence-based protocol for prophylactic antibiotics in open fractures: improved antibiotic stewardship with no increase in infection rates. Journal of Trauma and Acute Care Surgery. 2014;77(3):400-8.
Vessal G, Namazi S, Davarpanah M, Foroughinia F. Evaluation of prophylactic antibiotic administration at the surgical ward of a major referral hospital, Islamic Republic of Iran. Eastern Mediterranean health journal= La revue de sante de la Mediterranee orientale= al-Majallah al-sihhiyah li-sharq al-mutawassit. 2011;17(8):663-8.
Al-Momany NH, Al-Bakri AG, Makahleh ZM, Wazaify MM. Adherence to international antimicrobial prophylaxis guidelines in cardiac surgery: a Jordanian study demonstrates need for quality improvement. Journal of Managed Care Pharmacy. 2009;15(3):262-71.
Safargholi S, Mousavi F, Faghani Y, Najari S. Adherence to international and national prophylaxis guidelines in surgical wards of Boali hospital in Tehran in 1390. Iranian journal of infectious diseases and tropical medicine. 2013;17(59):23-7.
Durando P, Bassetti M, Orengo G, Crimi P, Battistini A, Bellina D, et al. Adherence to international and national recommendations for the prevention of surgical site infections in Italy: results from an observational prospective study in elective surgery. American journal of infection control. 2012;40(10):969-72.
Singer AJ, Hollander JE, Quinn JV. Evaluation and management of traumatic lacerations. New England Journal of Medicine. 1997;337(16):1142-8.
- Abstract Viewed: 5238 times
- PDF (فارسی) Downloaded: 607 times
- HTML (فارسی) Downloaded: 125 times