The Improvement Rate of Otitis Media with Effusion in Children under Gastroesophageal Reflux Therapy
Journal of Otorhinolaryngology and Facial Plastic Surgery,
Vol. 7 No. 1 (2021),
28 July 2021
,
Page 1-5
https://doi.org/10.22037/orlfps.v7i1.35628
Abstract
Background: Otitis media with effusion (OME) is one of the most common causes of hearing impairment in children and if not treated, can result in many complications. It seems that gastroesophageal reflux disease (GERD) plays an important role in OME.
Aim: to determine the improvement rate of otitis media with effusion in children under gastroesophageal reflux therapy.
Methods: The study was conducted as a retrospective study. Medical records of forty children with OME were reviewed. Some patients were treated with antibiotic and anti-reflux. The others were managed only with antibiotic. All patients were treated for 2 weeks. Two weeks after treatment complement, the response rates of patients were determined by clinical examination and tympanometry. Type A, C, and B tympanometry were interpreted as a good, moderate, and no response respectively. Pre-and post-treatment conditions were compared.
Results: Overall 78 ears (40 in in the anti-reflux therapy group and 38 in the other group) were enrolled in the survey. The overall good, moderate, and no responses to medical treatment were 35.9%, 35.9%, and 28.2%, respectively. Among 40 ears in the anti-reflux therapy group, the rates of good, moderate, and no response were 50%, 37.5%, and 12.5%, respectively. These rates in 38 other ears were 21%, 34.2%, and 44.8% respectively. The differences between two groups were statistically significant (all p-value of <0.05).
Conclusion: Anti-reflux therapy should be considered as an essential component of medical management in the children with OME.
- Otitis media with effusion; Gastro esophageal reflux; Laryngopharyngeal reflux; Anti-reflux; Otitis media/serous.
How to Cite
References
2. Amer HS, El-Anwar MW, Elfeky AE. The Efficacy of Adjuvant Intratympanic Steroid Treatment for Otitis Media with Effusion in Children. Int Arch Otorhinolaryngol 2016; 20(3):244–7.
3. Kahrilas P, Yadlapati R, Roman S. Emerging dilemmas in the diagnosis and management of gastroesophageal reflux disease. F1000Res 2017sep;6:1748.
4. Abd El-Fattah AM, Abdul Maksoud GA, Ramadan AS, Abdalla AF, Abdel Aziz MM. Pepsin assay: a marker for reflux in pediatric glue ear. Otolaryngol Head Neck Surg 2007 Mar;136(3):464-70.
5. Petrova LG, Chaĭkovskiĭ VV, Rybak PR. Pharyngolaryngeal reflux as one of the causes of chronic excretory otitis media. Vestnik otorinolaringologii 2013(1):19-21.
6. Kong K, Lannigan FJ, Morris PS, Leach AJ, O'Leary SJ. Ear, nose and throat surgery: All you need to know about the surgical approach to the management of middle‐ear effusions in Australian Indigenous and non‐Indigenous children. J Paediatr Child Health 2017Nov;53(11):1060-4.
7. Doğru M, Kuran G, Haytoğlu S, Dengiz R, Arıkan OK. Role of laryngopharyngeal reflux in the pathogenesis of otitis media with effusion. J Int Adv Otol 2015Apr; 11(1): 66-71.
8. Rosenfeld RM, Shin JJ, Schwartz SR, et al. Clinical practice guideline: otitis media with effusion (update). Otolaryngol Head Neck Surg 2016 Feb;154(1_suppl):S1-S41.
9. Yüksel F, Doğan M, Karataş D, Yüce S, Şentürk M, Külahlı İ. Clinical presentation of gastroesophageal reflux disease in children with chronic otitis media with effusion. J craniofac surg 2013 Mar;24(2):380-3.
10. O’reilly RC, Soundar S, Tonb D, et al. The role of gastric pepsin in the inflammatory cascade of pediatric otitis media. JAMA Otolaryngol Head Neck Surg 2015Apr;141(4):350-7.
11. McCoul ED, Goldstein NA, Koliskor B, Weedon J, Jackson A, Goldsmith AJ. A prospective study of the effect of gastroesophageal reflux disease treatment on children with otitis media. Arch Otolaryngol Head Neck Surg 2011Jan;137(1):35-41.
12. Poelmans J, Tack J, Feenstra L. Chronic middle ear disease and gastroesophageal reflux disease: a causal relation? Otol neurotol 2001 Jul;22(4):447-50.
13. Butler CS, Williams RG. The Etiology, Pathophysiology, and Management of Otitis Media with Effusion. Curr Infect Dis Rep 2003Jun; 5(3): 205-12.
14. He Z, O’Reilly RC, Mehta D. Gastric pepsin in middle ear fluid of children with otitis media: clinical implications. Curr allergy asthma rep 2008 Nov;8(6):513-8.
15. Luo HN, Yang QM, Sheng Y, et al. Role of pepsin and pepsinogen: linking laryngopharyngeal reflux with otitis media with effusion in children. Laryngoscope 2014 Jul;124(7):E294-300.
16. Formánek M, Zeleník K, Komínek P, Matoušek P. Diagnosis of extraesophageal reflux in children with chronic otitis media with effusion using Peptest. Int j pediatr otorhinolaryngol 2015 May;79(5):677-9.
17. Abdel-aziz MM, El-Fattah AM, Abdalla AF. Clinical evaluation of pepsin for laryngopharyngeal reflux in children with otitis media with effusion. Int j pediatr otorhinolaryngol 2013 Oct;77(10):1765-70.
18. Poelmans J, Tack J, Feenstra L. Prospective study on the incidence of chronic ear complaints related to gastroesophageal reflux and on the outcome of antireflux therapy. Ann Otol Rhinol Laryngol 2002 Oct;111(10):933-8.
19. Buyruk A, Osma Ü, Yılmaz MD, Eyigör H. Pepsinogen identification in the middle ear fluid of children with otitis media with effusion. Kulak burun bogaz ihtis derg 2016;26(2):73-8.
20. Górecka-Tuteja A, Jastrzębska I, Składzień J, Fyderek K. Laryngopharyngeal reflux in children with chronic otitis media with effusion. J neurogastroenterol motil 2016 Jul;22(3):452-8.
21. Saki N, Samarbaf Zadeh AR, Sheikhpour Jonaky R, Noori SM, Kayedani GA, Nikakhlagh S. The prevalence rate of Helicobacter pylori infection in, chronic otitis media with effusion patients. Jundishapur J Microbiol 2014 Mar;7(3):E15694.
22. Boronat-Echeverría N, Aguirre-Mariscal H, Carmolinga-Ponce M, et al. Helicobacter pylori detection and clinical symptomatology of gastroesophageal reflux disease in pediatric patients with otitis media with effusion. Int j pediatr otorhinolaryngol 2016 Aug;87:126-9.
23. Velepic MM, Velepic MS, Starcevic R, Manestar D, Rozmanic V. Gastroesophageal reflux and sequelae of chronic tubotympanal disorders in children. Acta otolaryngol 2004 Oct;124(8):914-7.
24. Aydın E, Taştan E, Aydoğan F, Arslan N, Karaca G. Role of nasopharyngeal reflux in the etiology of otitis media with effusion. J Otolaryngol Head Neck Surg 2011 Dec;40(6):499-503.
- Abstract Viewed: 137 times
- PDF Downloaded: 206 times