Challenging Approaches in Combating Streptococcus Pneumonia Infection
Archives of Advances in Biosciences,
Vol. 11 No. 2 (2020),
16 May 2020
AbstractContext: Streptococcus pneumoniae [pneumococcus] induces a large variety of the diseases burden such as bacteremia, meningitis, otitis media and pneumonia in human. Among these, the meningitis can be disclosed with long-lost diseases sequelae. Over the last decades, various recommendations and consensus were released to better manage this major respiratory disease.
Evidence Acquisition: However, there is a controversy among the clinicians about the best strategy in dealing with this chronic infection. In brief, using proper antibiotics or conjugate vaccine to battle this bacterium is a critical question for the clinical setting.
Results: Taken together, it seems that the best possible adopted strategy is to apply the pneumococcal conjugate vaccines in management due to the following two reasons: 1) reducing the bacterial antibiotic resistance rates and 2) decreasing the prevalence of pneumoniae mortality and morbidity at global scale
Conclusion: Conclusively, continuous surveillance surveys determining antibiotic resistance seem inevitable to track pneumococcal genetical variable populations for both successful antibiotic therapy and proper vaccination.
- Streptococcus pneumoniae
- antibiotic resistance
- serotype 19A
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