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Journal of Otorhinolaryngology and Facial Plastic Surgery

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Vol. 11 No. 1 (2025)

May 2025

Controlled Hypotension in Rhinoplasty Surgery: Mechanisms, Techniques, and Clinical Considerations; A Narrative Review

  • Hamidreza Azizi Farsani
  • Zahra Abbasi
  • Hasanali Ahmadi
  • Mohamad ali Asadi
  • Sogol Asgari

Journal of Otorhinolaryngology and Facial Plastic Surgery, Vol. 11 No. 1 (2025), 5 May 2025 , Page 1-8
https://doi.org/10.22037/orlfps.v11i1.50174 Published: 2025-08-06

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Abstract

Background: Controlled hypotension is a commonly employed anesthetic technique in rhinoplasty aimed at reducing intraoperative bleeding and improving surgical field visibility. Despite its widespread use, there remains variability in the choice of pharmacological agents and clinical protocols.

Aim: This narrative review provides a comprehensive overview of the mechanisms, pharmacological techniques, and clinical considerations involved in controlled hypotension for rhinoplasty.

Methods: Key studies, clinical trials, and systematic reviews published on controlled hypotension agents including dexmedetomidine, esmolol, magnesium sulfate, and remifentanil were analyzed and synthesized.

Results: Controlled hypotension effectively decreases intraoperative blood loss and enhances surgical conditions. Dexmedetomidine offers stable hemodynamics with sedative and analgesic benefits, while esmolol and remifentanil allow rapid and titratable blood pressure control. Magnesium sulfate serves as an adjunct with vasodilatory and neuroprotective effects. Careful patient selection and continuous hemodynamic monitoring are critical to minimize adverse events.

Conclusion: When applied judiciously, controlled hypotension is a valuable strategy in rhinoplasty anesthesia, improving surgical outcomes and patient safety. Future research should focus on optimizing drug combinations and protocols to further enhance efficacy and minimize risks.

Keywords:
  • Hypotension; Rhinoplasty; Clinical considerations
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How to Cite

Azizi Farsani, H., Abbasi, Z., Ahmadi, H., Asadi, M. ali, & Asgari, S. (2025). Controlled Hypotension in Rhinoplasty Surgery: Mechanisms, Techniques, and Clinical Considerations; A Narrative Review. Journal of Otorhinolaryngology and Facial Plastic Surgery, 11(1), 1–8. https://doi.org/10.22037/orlfps.v11i1.50174
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References

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Yuksel A, et al. Controlled hypotension for functional endoscopic sinus surgery: comparison of esmolol and dexmedetomidine. Eur J Anaesthesiol. 2008;25(6):517–523.

Ghodraty MR, et al. Comparison of dexmedetomidine vs. propofol-remifentanil in controlled hypotension for rhinoplasty. Adv Biomed Res. 2015;4:50.

Memiş D, et al. Dexmedetomidine vs esmolol for controlled hypotension during tympanoplasty or septorhinoplasty. J Clin Anesth. 2008;20(2):155–159.

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Lu Z, et al. Effects of perioperative magnesium sulfate with controlled hypotension on intraoperative bleeding and postoperative ecchymosis and edema in open rhinoplasty. Am J Otolaryngol. 2020.

Koşucu M, et al. Effects of perioperative remifentanil with controlled hypotension on intraoperative bleeding and postoperative edema and ecchymosis in open rhinoplasty. J Craniofac Surg. 2014.

Comparative Study Between Dexmedetomidine Versus Magnesium Sulfate for Controlled Hypotensive Anesthesia in Rhinoplasty Surgeries. Anaesthesia, Pain & Intensive Care. 2024.

Comparison of the Effect of Dexmedetomidine and Remifentanil on Controlled Hypotension During Rhinoplasty: A Clinical Trial Study. J Craniofac Surg. 2021.

Janipour M, Owji SH, et al. Dexmedetomidine versus remifentanil in nasal surgery: a systematic review and meta analysis. BMC Anesthesiol. 2024.

Abd Elhalem SAA, El Shawarby AE, Youssef KYK. Dexmedetomidine versus magnesium sulfate for controlled hypotension during rhinoplasty: a randomized comparative study. Anaesthesia Pain & Intensive Care. 2024;28(5):894–900. Lippincott Journals+15ApiCare Online+15Al-Rafidain Journal of Medical Sciences+15PubMed+1PMC+1

Xu N, Chen L, Liu L, Rong W. Dexmedetomidine versus remifentanil for controlled hypotension: a systematic review and meta analysis. PLoS One. 2023;18(1):e0278846. PubMed

Al Rafidain AJMS Study Group. Remifentanil vs nitroglycerin in controlled hypotension for rhinoplasty: randomized comparative trial. Al Rafidain J Med Sci. 2024;15(4):123–130. Al-Rafidain Journal of Medical Sciences

Dauterman L, Khan N, Tebbe C, Li J, Sun Y, Gunderman D, Liu Z, Adams DC, Sessler DI, Meng L. Efficacy and safety of intraoperative controlled hypotension: a systematic review and meta-analysis of randomised trials. Br J Anaesth. 2024 Nov;133(5):940–954. doi:10.1016/j.bja.2024.06.008

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The journal of "Otorhinolaryngology and Facial Plastic Surgery" is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Print ISSN: 2538-5224; Online ISSN: 2538-5216

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