Nasopharyngeal Inflammatory Pseudotumor: A Case Presenting with Nasal Congestion and Hearing Disorder
Journal of Otorhinolaryngology and Facial Plastic Surgery,
Vol. 9 No. 1 (2023),
2 September 2023
https://doi.org/10.22037/orlfps.v9i1.44881
Abstract
Background: Inflammatory pseudotumor (IP) is a collection of histocytes, and inflammatory cells including plasma cells, lymphocytes, eosinophils, and fibroblasts. The IP in the nasopharyngeal space is exceedingly rare. If left untreated it may cause permanent and serious complications.
Case presentation: A 46-year-old man with left nasal congestion, and a hearing decrement in his left ear was admitted to Loghman-hakim Hospital. In audiometric evaluations, there was a 20 decibels gap in the hearing threshold between two ears. In nasopharyngoscopy, there was a large gray-to-white mass with intact epithelia in the nasopharynx. In a computed tomography scan, a large soft mass in the left nasopharynx, with no evidence of bone destruction. Magnetic resonance imaging (MRI) homogenous isointense and hypointense mass in T1-weighted and T2-weighted images, respectively. Based on all the investigations, the risk of malignancy was considered low. As a result, the final diagnosis of IP was considered for him.
Discussion: IP can occur anywhere in the body and encompasses a diverse range of masses, including inflammatory myofibroblastic tumors, IPTs of lymph nodes, orbit, and spleen, genitourinary pseudosarcomatous, and post-infectious or reparative disorders. The tumors usually affect children and young adults, and the precise incidence and prevalence of IPs are difficult to estimate. The main treatment is surgical resection, corticosteroids, or both, with alternative treatments including small molecule inhibitors, immunoglobulin, and radiotherapy.
Conclusion: Sinonasal IPs are exceedingly rare. In this article, we reported a mid-aged man with an IP in his left nasopharynx space.
- Sinonasal; Inflammatory pseudotumor; Hearing disorder; Nasal congestion.
How to Cite
References
Huang WH, Dai YC. Inflammatory pseudotumor of the nasal cavity. Am J Otolaryngol. 2006 Jul-Aug;27(4):275-7. PubMed PMID: 16798408. Epub 2006/06/27. eng. Web of Science
Coffin CM, Watterson J, Priest JR, Dehner LP. Extrapulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor). A clinicopathologic and immunohistochemical study of 84 cases. Am J Surg Pathol. 1995 Aug;19(8):859-72. PubMed PMID: 7611533. Epub 1995/08/01. eng. Web of Science
Li J, Wang M, Li W, Tao Y, Shi X. Inflammatory Pseudotumor in the Nasal Cavity and Sinuses: A Case Report and Associated Literature Review. Ear Nose Throat J. 2021 Dec;100(10_suppl):897S-901S. PubMed PMID: 32419496. Epub 2020/05/19. eng.
Ortlip TE, Drake VE, Raghavan P, Papadimitriou JC, Porter NC, Eisenman DJ, et al. Inflammatory Pseudotumor of the Temporal Bone: A Case Series. Otol Neurotol. 2017 Aug;38(7):1024-31. PubMed PMID: 28570415. Pubmed Central PMCID: PMC5762198. Epub 2017/06/02. eng.
Devaney KO, Lafeir DJ, Triantafyllou A, Mendenhall WM, Woolgar JA, Rinaldo A, et al. Inflammatory myofibroblastic tumors of the head and neck: evaluation of clinicopathologic and prognostic features. Eur Arch Otorhinolaryngol. 2012 Dec;269(12):2461-5. PubMed PMID: 22588194. Epub 2012/05/17. eng.
Gale N, Zidar N, Podboj J, Volavsek M, Luzar B. Inflammatory myofibroblastic tumour of paranasal sinuses with fatal outcome: reactive lesion or tumour? J Clin Pathol. 2003 Sep;56(9):715-7. PubMed PMID: 12944561. Pubmed Central PMCID: PMC1770050. Epub 2003/08/29. eng.
Maruya S, Miura K, Tada Y, Masubuchi T, Nakamura N, Fushimi C, et al. Inflammatory pseudotumor of the parapharyngeal space: a case report. Auris Nasus Larynx. 2010 Jun;37(3):397-400. PubMed PMID: 19857937. Epub 2009/10/28. eng.
Kansara S, Bell D, Johnson J, Zafereo M. Head and neck inflammatory pseudotumor: Case series and review of the literature. Neuroradiol J. 2016 Dec;29(6):440-6. PubMed PMID: 27650653. Pubmed Central PMCID: PMC5131759. Epub 2016/09/22. eng.
- Abstract Viewed: 150 times
- PDF Downloaded: 96 times