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  4. Original Article

Vol. 8 No. 1 (2022)

January 2022

Evaluation of the Association between Serum Levels of Vitamin D and Benign Paroxysmal Positional Vertigo (BPPV): A Case-Control Study

  • Adel Imani
  • Mahdi Khajavi
  • Amir Hossain Ghazizadeh Hashemi
  • Narges Bazgir
  • Farzin Davodi
  • Mohammadsmaeil Kordjazi
  • Mahya Mohammadi

Journal of Otorhinolaryngology and Facial Plastic Surgery, Vol. 8 No. 1 (2022), 25 January 2022 , Page 1-6
https://doi.org/10.22037/orlfps.v8i1.39215 Published: 2022-08-22

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Abstract

Background: Benign paroxysmal positional vertigo (BPV) is the most common cause of the high prevalence of vertigo. Today, BPV is caused by the separation of autochthonous particles from the macular atrial. As a result, these particles float in a semicircular canal and change position by gravity. The majority of vertigo causes arise from the inner ear.

Aim: This study aims to measure the vitamin D level in patients with BPPV who visited Loghman Hakim Hospital clinics and compare the results with controls.

Methods: This comparative study evaluated the effect of vitamin D on reducing BPV. Demographic information of patients was collected through interviews. The physical examinations were recorded through a questionnaire. For the group with BPPV, we did the Epley maneuver and measured the vitamin D level. We compared the vitamin D levels of these patients with the matched control group.

Results: In this study, 148 patients were evaluated. Sixty-three patients were male, and 85 patients were female. All case and control patients were tested for vitamin D levels. Of 93 patients with benign vertigo, 39 (41.9%) patients had normal vitamin D levels, and 54(58.1%) patients had below normal. In the control group, 43 (78.2%) patients had normal vitamin D, and 12 (21.8%) patients had less than normal. There was a statistically significant difference between the two groups.

Conclusion: The present study indicated that BPV was more prevalent in people with vitamin D deficiency, and vitamin D treatment could effectively control and reduce the prevalence of this disease.

Keywords:
  • Vitamin D; Serum Levels; Benign Paroxysmal Positional Vertigo.
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How to Cite

Imani, A., Khajavi, M. ., Ghazizadeh Hashemi , A. H. ., Bazgir, N. ., Davodi, F., Kordjazi, M. ., & Mohammadi, M. . (2022). Evaluation of the Association between Serum Levels of Vitamin D and Benign Paroxysmal Positional Vertigo (BPPV): A Case-Control Study . Journal of Otorhinolaryngology and Facial Plastic Surgery, 8(1), 1–6. https://doi.org/10.22037/orlfps.v8i1.39215
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References

1. You P, Instrum R, Parnes L. Benign paroxysmal positional vertigo. Laryngoscope Investig Otolaryngol. 2019 Feb 1;4(1):116.
2. Imai T, Takeda N, Ikezono T, Shigeno K, Asai M, Watanabe Y, et al. Classification, diagnostic criteria and management of benign paroxysmal positional vertigo. Auris Nasus Larynx. 2017 Feb 1;44(1):1–6.
3. Dix MR, Hallpike CS. The Pathology, Symptomatology and Diagnosis of Certain Common Disorders of the Vestibular System. J R Soc Med. 1952 Sep 1;45(6):341–54.
4. Califano L, Salafia F, Mazzone S, Melillo MG, Califano M. Anterior canal BPPV and apogeotropic posteriorcanal BPPV: two rare forms of vertical canalolithiasis. Acta Otorhinolaryngol Ital. 2014;34(3):189.
5. Von Brevern M, Radtke A, Lezius F, Feldmann M, Ziese T, Lempert T, et al. Epidemiology of benign paroxysmal positional vertigo: A population based study. J Neurol Neurosurg Psychiatry. 2007 Jul;78(7):710–5.
6. Von Brevern M, Bertholon P, Brandt T, Fife T, Imai T, Nuti D, et al. Benign paroxysmal positional vertigo: Diagnostic criteria. J Vestib Res Equilib Orientat. 2015 Oct 15;25(3–4):105–17.
7. Kim HJ, Park JH, Kim JS. Update on benign paroxysmal positional vertigo. J Neurol. 2021 May 1;268(5):1995–2000.
8. Chen J, Zhao W, Yue X, Zhang P. Risk factors for the occurrence of benign paroxysmal positional vertigo: A systematic review and meta-analysis. Front Neurol. 2020;11(June):1–12.
9. Whitman GT, Baloh RW. Seasonality of benign paroxysmal positional vertigo. JAMA Otolaryngol Head Neck Surg. 2015 Feb 1;141(2):188–9.
10. Bazoni JA, Mendes WS, Meneses-Barriviera CL, Melo JJ, De Souza Pinho Costa V, De Denilson CT, et al. Physical activity in the prevention of benign paroxysmal positional vertigo: Probable association. Int Arch Otorhinolaryngol. 2014;18(4):387–90.
11. Nuti D, Masini M, Mandalà M. Benign paroxysmal positional vertigo and its variants. Handb Clin Neurol. 2016;137:241–56.
12. Karataş A, Acar Yüceant G, Yüce T, Hacı C, Taylan Cebi I, Salviz M. Association of Benign Paroxysmal Positional Vertigo with Osteoporosis and Vitamin D Deficiency: A Case Controlled Study. J Int Adv Otol. 2017;13(2):259–65.
13. Jeong SH, Kim JS, Shin JW, Kim S, Lee H, Lee AY, et al. Decreased serum vitamin D in idiopathic benign paroxysmal positional vertigo. J Neurol. 2013 Mar;260(3):832–8.
14. Jeong SH, Choi SH, Kim JY, Koo JW, Kim HJ, Kim JS. Osteopenia and osteoporosis in idiopathic benign positional vertigo. Neurology. 2009 Mar 24;72(12):1069–76.
15. Oghalai JS, Manolidis S, Barth JL, Stewart MG, Jenkins HA. Unrecognized benign paroxysmal positional vertigo in elderly patients. Otolaryngol Head Neck Surg. 2000 May 1;122(5):630–4.
16. Murad MH, Elamin KB, Abu Elnour NO, Elamin MB, Alkatib AA, Fatourechi MM, et al. Clinical review: The effect of vitamin D on falls: a systematic review and meta-analysis. J Clin Endocrinol Metab. 2011 Oct;96(10):2997–3006.
17. Bischoff-Ferrari HA, Dawson-Hughes B, Willett WC, Staehelin HB, Bazemore MG, Zee RY, et al. Effect of Vitamin D on falls: a meta-analysis. JAMA. 2004 Apr 28;291(16):1999–2006.
18. Minasyan A, Keisala T, Zou J, Zhang Y, Toppila E, Syvälä H, et al. Vestibular dysfunction in vitamin D receptor mutant mice. J Steroid Biochem Mol Biol. 2009 Apr;114(3–5):161–6.
19. Thalmann R, Ignatova E, Kachar B, Ornitz DM, Thalmann I. Development and maintenance of otoconia: biochemical considerations. Ann N Y Acad Sci. 2001;942:162–78.
20. Ross MD. Calcium ion uptake and exchange in otoconia. Adv Otorhinolaryngol. 1979;25:26–33.
21. Middleton K, Fish DE. Enhanced Reader1.pdf. Curr Rev Musculoskeletal Med. 2009. p. 94–104.
22. Influence of supplemental vitamin D on intensity of benign paroxysmal positional vertigo: A longitudinal clinical study - PubMed.
23. Talaat HS, Kabel AMH, Khaliel LH, Abuhadied G, El-Naga HAERA, Talaat AS. Reduction of recurrence rate of benign paroxysmal positional vertigo by treatment of severe vitamin D deficiency. Auris Nasus Larynx. 2016 Jun 1;43(3):237–41.
24. Gu X, Dong F, Gu J. Analysis of effect of 1α-hydroxyvitamin D3 on benign paroxysmal positional vertigo and risk factors. Exp Ther Med. 2018 Mar 1;15(3):2321–6.
25. Parham K, Leonard G, Feinn RS, Lafreniere D, Kenny AM. Prospective clinical investigation of the relationship between idiopathic benign paroxysmal positional vertigo and bone turnover: a pilot study. Laryngoscope. 2013 Nov;123(11):2834–9.
26. Yu S, Liu F, Cheng Z, Wang Q. Association between osteoporosis and benign paroxysmal positional vertigo: a systematic review. BMC Neurol. 2014 May 20;14(1).
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The journal of "Otorhinolaryngology and Facial Plastic Surgery" is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Print ISSN: 2538-5224; Online ISSN: 2538-5216

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