Typical Hemolytic Uremic Syndrome with Diffused Brain Ischemia as a Complication: A Case Report of a Child in Iran
Journal of Pediatric Nephrology,
Vol. 2 No. 1 (2014),
,
Page 39-42
https://doi.org/10.22037/jpn.v2i1.4979
Abstract
Hemolytic uremic syndrome includes hemolytic anemia, acute kidney injury, and thrombocytopenia. In this article, a child with hemolytic uremic syndrome (HUS) and acute nervous system involvement is reported. The patient was a 22-month-old boy who presented with hemorrhagic diarrhea and anuria. He was admitted by the impression of HUS and received supportive care such as acute peritoneal dialysis and packed cell infusion. During recovery period and after the beginning of the fifth session of dialysis, the child suddenly experienced loss of consciousness and focal convulsion in some extremities which led to hemiparesis of the left side of the body, and speech and swallowing impairment. The patient underwent a diagnostic and therapeutic process and was followed for one year. Any organ damage such as nervous system involvement and an appropriate period of follow up should be considered in a typical HUS syndrome, especially in pediatric patients.
Keywords:Hemolytic-Uremic Syndrome; Brain Ischemia; Infarction; Child; Iran.
How to Cite
References
1. Han DK, Baek HJ, Cho YK, et al. A case of atypical hemolytic uremic syndrome as an early manifestation of acute lymphoblastic leukemia. Korean J Pediatr 2010 February;53(2) :253-257.
Noris M, Remuzzi G. Hemolytic uremic syndrome. J Am Soc Nephrol. 2005 Apr;16(4):1035-50.
Nathanson S, Kwon T, Elmaleh M, et al. Acute neurological involvement in diarrhea-associated hemolytic uremic syndrome. Clin J Am Soc Nephrol. 2010 Jul;5(7):1218-28.
Eriksson KJ, Boyd SG, Tasker RC. Acute neurology and neurophysiology of haemolytic-uraemic syndrome. Arch Dis Child. 2001 May;84(5):434-5.
Edey MM, Mead PA, Saunders RE, et al. Association of a factor H mutation with hemolytic uremic syndrome following a diarrheal illness. Am J Kidney Dis 2008; 51: 487-490.
Gallo GE, Gianantonio CA: Extrarenal involvement in dairrhoea- associated haemolytic-uraemic syndrome. Pediatr Nephrol 1995; 9: 117-119.
Loirat C, Frémeaux-Bacchi V. Atypical Hemolytic Uremic Syndrome. Orphanet J Rare Dis. 2011 Sep 8; 6:60. doi: 10.1186/1750-1172-6-60.
- Abstract Viewed: 171 times
- PDF Downloaded: 256 times