The Evaluation of Serum Vitamin D Levels in Pediatric Patients With Vesicoureteral Reflux
Journal of Pediatric Nephrology,
Vol. 10 No. 2 (2022),
1 October 2022
,
Page 91-95
https://doi.org/10.22037/jpn.v10i2.38193
Abstract
Background and Aim: Vesicoureteral Reflux (VUR) refers to the pathological return
of urine from the bladder to the ureter and then to the kidney in some patients. Vitamin D
deficiency is associated with some renal diseases. This study examines the relationship
between vitamin D deficiency and urinary reflux.
Methods: In this cross-sectional study, 200 children referred to Amir Kabir Hospital
in Arak, Iran, were divided into 2 groups of patients with VUR (n=100) and another
group of pediatric participants considered healthy and had no findings of VUR (n=100).
Confirmation of diagnosis was performed via voiding cystourethrogram. Serum vitamin
D levels were evaluated by the Enzyme-Linked Immunosorbent Assay (ELISA) method
in all participants.
Results: The results showed that the rate of vitamin D deficiency was 38% and 42%
in the case and control groups, respectively. Therefore, no significant correlation was
observed between the two study groups in terms of vitamin D deficiency. This finding
was regardless of VUR complications affecting vitamin D metabolism.
Conclusion: We assume that VUR is a complicated condition with several
complications, and the relationship of each complication with vitamin D deficiency has
been determined to some extent in previous studies; however, this condition cannot be
considered an independent factor leading to vitamin D deficiency.
- Vitamin D Deficiency
- Vesicoureteral Reflux
- Complications
- Pediatrics
How to Cite
References
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