Profile of Pediatric Kidney Transplantation at a Tertiary Care Centre in Southern India
Journal of Pediatric Nephrology,
Vol. 5 No. 1 (2017),
,
Page 1-5
https://doi.org/10.22037/jpn.v5i1.16339
Abstract
Introduction: Renal transplantation offers the best chance of survival to children with End Stage Renal Disease (ESRD). Patient survival and growth are superior in children with a renal allograft compared to dialysis. The aim of the study was to evaluate the outcomes of pediatric transplants done at a tertiary care hospital in Kochi, India over the study period.
Materials and Methods: In this retrospective study, the data of children who underwent renal transplantation at Amrita Institute of Medical Sciences from 2002 to 2016 Kochi were analyzed.
Results: Thirty-four children underwent renal transplantation over a 14-year period. Thirty-three underwent live related transplant whereas one underwent deceased donor transplantation. The mean age and weight of the recipients at transplantation was 14.3 years and 35.7 kg, respectively. Fourteen children were boys and twenty were girls. Thirty-one patients underwent hemodialysis prior to transplant, 2 were taken up preemptively, and 1 patient was on continuous ambulatory peritoneal dialysis. There were 5 documented urinary tract infections. No surgical complications were noted in the immediate post-transplant period. There were 5 episodes of acute rejection (14.7%). Two cases experienced Delayed Graft Function and the patient survival rate was 100%.
Conclusions: Renal transplantation is a viable option to manage children with ESRD with satisfactory long term results and can be done in a developing nation’s set-up.
Keywords: Kidney transplantation; India; Child.
- Kidney transplantation
- Children
- India
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References
Soylemezoglu O, Duzova A, Yalcinkaya F, Arinsoy T, Suleymanlar G. Chronic Renal Disease in children aged 5-18 years: a population based survey in Turkey, the CREDIT-C study. Nephrol.Dial.Transplant. 2012; suppl 3. 1999-2009.
Warady BA, Chadha. Chronic kidney disease in children: The global perspective. Pediatr Nephrol. 2007; 22:1999-2007.
Avner ED, Chavers B, Sullivan EK, Tejani A. Renal transplantation and chronic dialysis in children: 1993 Annual Report of the North American Pediatric Renal Transplant Co- operative study. Pediatr Nephrol. 1995; 9:61–73.
Kanitkar M, Chronic Kidney Disease in children: An Indian Perspective. Medical Journal Armed Forces India, 2009; 65: 45-49.
McDonald SP, Craig JC, Australian and New Zealand Pediatric Nephrology Association. Long-term survival of children with end-stage renal disease. N Engl J Med. 2004;350:2654.
Sathe, Kiran P. et al. Pediatric renal transplantation: 5 years experience from Jaslok Hospital, Mumbai Indian Journal of Transplantation 2014;8:3–7.
Gulati S · Kumar A · Sharma RK et al. Outcome of pediatric renal transplants in a developing country.Pediatr Nephrol 2004; 19:96–100.
Phadke K, Iyengar A, Karthik S, Kumar A, Olakkengil S. Pediatric Renal Transplantation: The Bangalore Experience. Indian Pediatr. 2006; 43: 44-48.
North American Pediatric Renal Transplant Cooperative Study (NAPRTCS): 2010 Annual report. Rockville, MD. Available from: http://www.naprtcs.org
The North American Pediatric Renal Trials and Collaborative Studies 2014 Annual Report. Available at: https://web.emmes.com/study/ped/annlrept/annlrept.html
Chacko B, Rajamanickam T, Neelakantan N, V. Tamilarasi, George T John. Pediatric Renal Transplantation – A single center experience of 15 years from India Pediatr Transplantation. 2007: 11: 844–849.
Kasiske BL, Snyder JJ, Matas AJ, Ellison MD, Gill JS, Kausz ATJ. Preemptive kidney transplantation: the advantage and the advantaged. Am Soc Nephrol. 2002; 13:1358.
Phadke K, Ballal S,. Venkatesh K, Sundar S. Pediatric Renal Transplantation: Indian experience. Indian Pediatr 1998; 35: 231-235.
Tejani A; Stablein et al. Analysis of rejection outcomes and implications-a report of the North American pediatric renal transplant cooperative study. Transplantation 1995; 59: 500-4.
Dharnidharka VR, Stablein DM, Harmon WE. Post-transplant infections now exceed acute rejection as cause for hospitalization: a report of the NAPRTCS. Am J Transplant. 2004; 4:384-9.
Silva A, Rodig N, Passerotti CP, et al. Risk factors for urinary tract infection after renal transplantation and its impact on graft function in children and young adults. J Urol. 2010; 184:1462.
Esezobor CI, Nourse P, Gajjar P. Urinary tract infection following kidney transplantation: frequency, risk factors and graft function. Pediatr Nephrol. 2012:651-7.
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