Holmium:YAG Laser for the Treatment of Genital and urethral Warts: Multicentre Prospective Evaluation of Safety and Efficacy Holmium:YAG Laser for the Treatment of Genital and urethral Warts
Journal of Lasers in Medical Sciences,
Vol. 12 (2021),
13 February 2021
,
Page e34
Abstract
Introduction: Genital condylomatosis is a highly contagious disease caused by the human papillomavirus (HPV). The aim of this prospective multicentre study was to evaluate the safety and efficacy of the Holmium: YAG (yttrium-aluminum-garnet) laser in the treatment of genital and intra-urethral warts; the secondary aim was to assess the patients’ postoperative satisfaction and cosmetic results.
Methods: From December 2016 to March 2019, patients with genital warts were prospectively enrolled in three hospitals. The inclusion criteria were male gender, age over 18 years old, and treatment-naïve. External and urethral genitalia warts were treated by the Holmium YAG laser. The follow-up analysis consisted of physical examination, flexible urethra-cystoscopy in case of meatal lesions, and administration of Dermatology Quality of Life Index (DLQI) and Patient Global Impression of Improvement (PGI-I) questionnaires at 1, 3, 6, and 12 months after surgery and subsequently yearly.
Results: Sixty patients were enrolled. The single treatment was effective in 57/60 patients (95%). At a mean follow-up of 26 months, recurrences occurred in 8 patients (13.3%). No peri- or postoperative complication occurred. An improvement in pre-operative condition was highlighted with PGI-I and DLQI questionnaires.
Conclusion: Our prospective multicentre study showed that holmium laser surgery seems to be a safe and effective treatment for external genital and urethral warts. Good dermatological outcomes aid to further improve patient satisfaction.
- Genital warts; Holmium laser; Patient satisfaction; Recurrence
How to Cite
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