Treatment of Congenital Melanocytic Nevi With a Dual-Wavelengths Copper Vapor Laser: A Case Series
Journal of Lasers in Medical Sciences,
Vol. 12 (2021),
13 Bahman 2021
Introduction: Congenital melanocytic nevus (CMN) is a severe challenge for dermatology. This pigmented skin lesion is undesirable for patients because of its localization in open areas of the body. Various visible and near-infrared laser systems and intense pulsed light (IPL) sources have been applied for CMN treatment. However, post-traumatic hyperpigmentation, structural changes, atrophy, and scarring due to non-specific thermal damage have been observed. Many patients have shown recurrence after treatment. Therefore, it highlights the need for testing new laser modalities for the management of CMN.
Methods: Two adult II Fitzpatrick phototype patients (a 55-year-old male and a 30-year-old female) with middle-sized facial CMN (on the forehead and lower eyelid) are presented. All patients were treated with dual-wavelength copper vapor laser (CVL) radiation at 511 nm and 578 nm wavelengths with a power ratio of 3:2. The average power was 0.7-0.85 W with an exposure time of 0.3 seconds. The spot size amounted to 1 mm.
Results: Both patients showed complete resolution of CMN after CVL treatments. CMN became crusted within a few days after the laser treatment and peeled off within seven days. No recurrences were observed during the follow-up period up to 24 months.
Conclusion: The middle-sized CMN can be successfully treated with dual-wavelength CVL radiation.
- Copper vapor laser; Melanocytic nevi; Selective pigmented treatment; Computer simulation; Blood vessel; Hyperpigmentation
How to Cite
Magaña M, Sánchez-Romero E, Magaña P, Beck-Magaña A, Magaña-Lozano M. Congenital melanocytic nevus: two clinicopathological forms. Am J Dermatopathol. 2015;37(1):31-37. doi: 10.1097/DAD.0000000000000183.
Alster TS, Lupton JR. Laser therapy for cutaneous hyperpigmentation and pigmented lesions. Dermatol Ther. 2001;14(1):46-54. doi: 10.1046/j.1529-8019.2001.014001046.x.
Fahradyan A, Wolfswinkel EM, Tsuha M, Reinisch JF, Magee 3rd W, Hammoudeh JA, et al. Cosmetically challenging congenital melanocytic nevi. Ann Plast Surg. 2019;82(5S Suppl 4):S306-S309. doi: 10.1097/sap.0000000000001766.
Rayala BZ, Morrell DS. Common skin conditions in children: congenital melanocytic nevi and infantile hemangiomas. FP Essent. 2017;453:33-37.
Sardana K, Chakravarty P, Goel K. Optimal management of common acquired melanocytic nevi (moles): current perspectives. Clin Cosmet Investig Dermatol. 2014;7:89-103. doi: 10.2147/CCID.S57782.
Eggen CAM, Lommerts JE, van Zuuren EJ, Limpens J, Pasmans SGM, Wolkerstorfer A. Laser treatment of congenital melanocytic naevi: a systematic review. Br J Dermatol. 2018;178(2):369-383. doi: 10.1111/bjd.16094.
Al-Hadithy N, Al-Nakib K, Quaba A. Outcomes of 52 patients with congenital melanocytic naevi treated with UltraPulse carbon dioxide and frequency doubled Q-switched Nd-Yag laser. J Plast Reconstr Aesthet Surg. 2012;65(8):1019-1028. doi: 10.1016/j.bjps.2012.03.003.
Bhatt N, Alster TS. Laser surgery in dark skin. Dermatol Surg. 2008;34(2):184-195. doi: 10.1111/j.1524-4725.2007.34036.x.
Bray FN, Shah V, Nouri K. Laser treatment of congenital melanocytic nevi: a review of the literature. Lasers Med Sci. 2016;31(1):197-204. doi: 10.1007/s10103-015-1833-3.
Helsing P, Mørk G, Sveen B. Ruby laser treatment of congenital melanocytic naevi– a pessimistic view. Acta Derm Venereol. 2006;86(3):235-237. doi: 10.2340/00015555-0041.
Lee MS, Jun HJ, Cho SH, Lee JD, Kim HS. Intense pulsed light alone and in combination with Erbium Yttrium-Aluminum-Garnet laser on small-to-medium sized congenital melanocytic nevi: single center experience based on retrospective chart review. Ann Dermatol. 2017;29(1):39-47. doi: 10.5021/ad.2017.29.1.39.
Kim YJ, Whang KU, Choi WB, Kim HJ, Hwang JY, Lee JH, et al. Efficacy and safety of 1,064 nm Q-switched Nd:YAG laser treatment for removing melanocytic nevi. Ann Dermatol. 2012;24(2):162-167. doi: 10.5021/ad.2012.24.2.162.
Grevelink JM, van Leeuwen RL, Anderson RR, Byers HR. Clinical and histological responses of congenital melanocytic nevi after single treatment with Q-switched lasers. Arch Dermatol. 1997;133(3):349-353. doi: 10.1001/archderm.1997.03890390089012.
Sherwood KA, Murray S, Kurban AK, Tan OT. Effect of wavelength on cutaneous pigment using pulsed irradiation. J Invest Dermatol. 1989;92(5):717-720. doi: 10.1016/0022-202X(89)90187-5.
Somyos K, Boonchu K, Somsak K, Panadda L, Leopairut J. Copper vapour laser treatment of café-au-lait macules. Br J Dermatol. 1996;135(6):964-968. doi: 10.1046/j.1365-2133.1996.d01-1103.x.
Ulrich M, Themstrup L, de Carvalho N, Manfredi M, Grana C, Ciardo S, et al. Dynamic optical coherence tomography in dermatology. Dermatology. 2016;232(3):298-311. doi: 10.1159/000444706.
Regazzetti C, De Donatis GM, Ghorbel HH, Cardot-Leccia N, Ambrosetti D, Bahadoran P, et al. Endothelial cells promote pigmentation through endothelin receptor B activation. J Invest Dermatol. 2015;135(12):3096-3104. doi: 10.1038/jid.2015.332.
Klyuchareva SV, Ponomarev IV, Pushkareva AE. Numerical modeling and clinical evaluation of pulsed dye laser and copper vapor laser in skin vascular lesions treatment. J Lasers Med Sci. 2019;10(1):44-49. doi: 10.15171/jlms.2019.07.
Ponomarev IV, Topchiy SB, Kazaryan MA, Pushkareva AE, Klyuchareva SV. Numerical simulation optimization of selective heating of blood vessels in “Port-Wine stains” under laser irradiation in various modes. Bull Lebedev Phys Inst. 2018;45(7):204-208. doi: 10.3103/S1068335618070035.
- Abstract Viewed: 562 times
- PDF Downloaded: 391 times