Evaluation of a Selected 8-Week Training Program Effectiveness on FGF21 and FGFR-1 Levels in Patients with Coronary Artery Bypass Graft Surgery (CABG)
SOREN Student Sports & Health Open Researches e-Journal: New-Approaches,
Vol. 2 No. 2 (1400),
5 September 2021
,
Page 24-30
https://doi.org/10.22037/soren.v2i2.35681
Abstract
Background and aim: Short-term exercise for patients with coronary artery bypass graft (CABG) can enhance the benefits of cardiorespiratory function, muscle strength, cardiac function, ventilation efficiency, hemodynamic function, and quality of life. According to the mentioned cases, the aim of the present study was to investigate the effect of a selected training program on FGF21 and FGFR-1 levels in CABG patients.
Methods: The research method was semi-experimental and the statistical population was heart patients after CABG surgery in Babol hospitals. For this purpose, 16 patients were selected by the available sampling method and divided into two groups of specialized and control exercises. Subjects in the experimental group participated in these sessions for 8 weeks and three sessions per week. The expression levels of the FGF21 and FGFR-1 were measured using the ELISA kit. The covariance and the dependent t-test analysis were used to determine the difference between groups and intragroup.
Results: The results showed that 8 weeks of the selected training program had a significant increase in the FGF21 level in CABG patients in the pre-test stage compared to the post-test stage (p<0.05), as well as in the FGF21 and FGFR1 levels in the training group compared to the control group (p<0.05).
Conclusion: It is possible that physical activity can increase FGF21 levels, which have an anti-inflammatory and anti-oxidant role.
- FGF21
- FGFR-1
- CABG patients
- Selected Training Program
How to Cite
References
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