Nesfatin-1 Response to Resistance Exercise in Young and Middle-aged Men
SOREN Student Sports & Health Open Researches e-Journal: New-Approaches,
Vol. 2 No. 1 (1400),
11 June 2021
,
Page 17-24
https://doi.org/10.22037/soren.v2i1.34680
Abstract
Background and aim: Nesfatin-1 response to one session resistance exercise in young and middle-aged men is unclear. The aim of the present study was to determine the effect of acute resistance exercise on the Nesfatin-1 response in young and middle-aged men.
Methods: For this purpose, 11 young men (20-30 years) and 10 middle-aged men (40-50 years) participated in this study. All subjects performed an acute resistance exercise test session (performing 4 sets at 6 stations: chest press, leg press, leg extension, shoulder bar, arm curl, seated lat pull-down with the intensity of 60% one repetition maximum). Blood samples were taken before and immediately after exercise to measure the concentration of Nesfatin-1 serum. Analysis of variance with repeated measures was used to evaluate the significance of intra-group and inter-group changes. Statistical analyzes were performed using SPSS22 at a significance level of p<0.05.
Results: The results showed that resistance exercise had no significant effect on Nesfatin-1 levels after exercise and there was no significant difference between Nesfatin response to resistance exercise in two different age groups (P>0.05).
Conclusion: The results of this study showed that one session of moderate intensity resistance exercise did not have a significant effect on the serum levels of Nesfatin -1 in young and middle-aged men. There was also no significant difference in Nesfatin response to acute exercise between young and middle-aged men.
- Appetite
- Resistance Exercise
- Age
- Nesfatin-1
How to Cite
References
Azizi F, Azad, L., Mirmiran, P. The prevalence of overweight, obesity and abdominal obesity in adults 13 Years Tehran 1998-2001. Journal of Medical Research. 2005; 29:123-9.
Alkhouri N, Gornicka A, Berk MP, Thapaliya S, Dixon LJ, Kashyap S, et al. Adipocyte apoptosis, a link between obesity, insulin resistance, and hepatic steatosis. Journal of Biological Chemistry. 2010; 285(5):3428-38.
Stensel D. Exercise, appetite and appetite-regulating hormones: implications for food intake and weight control. Annals of Nutrition and Metabolism. 2010; 57(Suppl. 2):36-42.
Tsuchiya T, Shimizu H, Yamada M, Osaki A, Oh‐I S, Ariyama Y, et al. Fasting concentrations of nesfatin‐1 are negatively correlated with body mass index in non‐obese males. Clinical endocrinology. 2010; 73(4):484-90.
Su Y, Zhang J, Tang Y, Bi F, Liu J-N. The novel function of nesfatin-1: anti-hyperglycemia. Biochemical and biophysical research communications. 2010; 391(1):1039-42.
Pan W, Hsuchou H, Kastin AJ. Nesfatin-1 crosses the blood-brain barrier without saturation. peptides. 2007; 28(11):2223-8.
Rabe K, Lehrke M, Parhofer K, Broedl U. Adipokines and insulin resistance. Molecular Medicine. 2008; 14(11-12):741.
Fasshauer M, Paschke R. Regulation of adipocytokines and insulin resistance. Diabetologia. 2003; 46(12):1594-603.
Trujillo M, Scherer P. Adipose tissue-derived factors: impact on health and disease. Endocrine reviews. 2006; 27(7):762.
Eriksson P, Reynisdottir S, Lönnqvist F, Stemme V, Hamsten A, Arner P. Adipose tissue secretion of plasminogen activator inhibitor-1 in non-obese and obese individuals. Diabetologia. 1998; 41(1):65-71.
Samad F, Yamamoto K, Loskutoff D. Distribution and regulation of plasminogen activator inhibitor-1 in murine adipose tissue in vivo. Induction by tumor necrosis factor-alpha and lipopolysaccharide. Journal of Clinical Investigation. 1996; 97(1):37.
Oh S, Shimizu H, Satoh T, Okada S, Adachi S, Inoue K, et al. Identification of nesfatin-1 as a satiety molecule in the hypothalamus. Nature. 2006; 443(7112):709-12.
Stengel A, Taché Y. Nesfatin-1—role as possible new potent regulator of food intake. Regulatory peptides. 2010; 163(1-3):18-23.
Oh S, Shimizu H, Satoh T, Okada S, Adachi S, Inoue K, et al. Identification of nesfatin-1 as a satiety molecule in the hypothalamus. Nature. 2006; 443(7112):709.
Ramanjaneya M, Chen J, Brown J, Tripathi G, Hallschmid M, Patel S, et al. Identification of Nesfatin-1 in Human and Murine Adipose Tissue: A Novel Depot-Specific Adipokine with Increased Levels in Obesity. Endocrinology. 2010; 151(7):3169.
Shimizu H, Mori M. The brain–adipose axis: a review of involvement of molecules. Nutritional neuroscience. 2005; 8(1):7-20.
Shimizu H, OH-i S, Okada S, Mori M. Nesfatin-1: an overview and future clinical application. Endocrine journal. 2009; 56(4):537-43.
Singh M. Exercise and aging. Clinics in Geriatric Medicine. 2004; 20(2):201-22.
Franzoni F, Galetta F, Morizzo C, Lubrano V, Palombo C, Santoro G, et al. Effects of age and physical fitness on microcirculatory function. Clinical Science. 2004; 106(3):329-36.
Jani B, Rajkumar C. Ageing and vascular ageing. British Medical Journal. 2006; 82(968):357.
Sacheck J, Cannon J, Hamada K, Vannier E, Blumberg J, Roubenoff R. Age-related loss of associations between acute exercise-induced IL-6 and oxidative stress. American Journal of Physiology- Endocrinology And Metabolism. 2006; 291(2):E340.
Szoke E, Shrayyef M, Messing S, Woerle H, van Haeften T, Meyer C, et al. Effect of aging on glucose homeostasis. Diabetes care. 2008; 31(3):539.
Wolden-Hanson T, Marck B, Smith L, Matsumoto A. Cross-sectional and longitudinal analysis of age-associated changes in body composition of male Brown Norway rats: association of serum leptin levels with peripheral adiposity. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 1999; 54(3):B99.
Li J-B, Nishida M, Kaimoto K, Asakawa A, Chaolu H, Cheng K-C, et al. Effects of aging on the plasma levels of nesfatin‑1 and adiponectin. Biomedical reports. 2014; 2(1):152-6.
Moradi M, Shabkhiz F, Khalafi M. The acute effect of aerobic exercise on hypothalamic nesfatin-1 gene expression in diabetic male rats with Streptozotocin. 2018.
Yang M, Zhang Z, Wang C, Li K, Li S, Boden G, et al. Nesfatin-1 action in the brain increases insulin sensitivity through Akt/AMPK/TORC2 pathway in diet-induced insulin resistance. Diabetes. 2012; 61(8):1959-68.
Hardie DG. AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy. Nature reviews Molecular cell biology. 2007; 8(10):774.
Lee YS, Kim WS, Kim KH, Yoon MJ, Cho HJ, Shen Y, et al. Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states. Diabetes. 2006; 55(8):2256-64.
Faraji H, TaghipoorAsrami A, Jalali SF, Enferadi F. The effect of concurrent exercise on PYY and NPY plasma levels in obese men. Tabari Journal of Preventive Medicine. 2016; 2(1):48-58.
Faraji H, Rahimi R, Dabbagh Nikookheslat S. Effect of an Acute Incremental Exercise on Plasma Peptide YY, Neuropeptide Y and IGF-1 Concentrations in Young Athletes. Annals of Applied Sport Science. 2014; 2(3):23-32.
Ghanbari-Niaki A, Kraemer RR, Soltani R. Plasma nesfatin-1 and glucoregulatory hormone responses to two different anaerobic exercise sessions. European journal of applied physiology. 2010:1-6.
Ghanbari-Niaki A, Kraemer RR, Soltani R. Plasma nesfatin-1 and glucoregulatory hormone responses to two different anaerobic exercise sessions. European journal of applied physiology. 2010; 110(4):863-8.
Bashiri J, Gholami F, Rahbaran A, Tarmahi V. Effect of single bout of aerobic exercise on serum Nesfatin-1 levels in non-athlete elderly men. 2012.
Algul S, Ozdenk C, Ozcelik O. Variations in leptin, nesfatin-1 and irisin levels induced by aerobic exercise in young trained and untrained male subjects. Biology of sport. 2017; 34(4):339.
Goebel M, Stengel A, Wang L, Lambrecht NW, Taché Y. Nesfatin-1 immunoreactivity in rat brain and spinal cord autonomic nuclei. Neuroscience letters. 2009; 452(3):241-6.
Goebel M, Stengel A, Wang L, Lambrecht NWG, Taché Y. Nesfatin-1 immunoreactivity in rat brain and spinal cord autonomic nuclei. Neuroscience letters. 2009; 452(3):241-6.
Guo Y, Liao Y, Fang G, Dong J, Li Z. Increased nucleobindin-2 (NUCB2) transcriptional activity links the regulation of insulin sensitivity in Type 2 diabetes mellitus. Journal of endocrinological investigation. 2013; 36(10):883-8.
Zhang Z, Li L, Yang M, Liu H, Boden G, Yang G. Increased plasma levels of nesfatin-1 in patients with newly diagnosed type 2 diabetes mellitus. Experimental and clinical endocrinology & diabetes. 2012; 120(02):91-5.
Dai R, Deng G, Sun Z, Liu Z, Qian Y, Han Y. Relation of serum and vitreous nesfatin‐1 concentrations with diabetic retinopathy. Journal of clinical laboratory analysis. 2017; 31(5):e22105.
Zhai T, Li S-Z, Fan X-T, Tian Z, Lu X-Q, Dong J. Circulating nesfatin-1 levels and type 2 diabetes: a systematic review and meta-analysis. Journal of diabetes research. 2017.
Suzuki K, Yamada M, Kurakake S, Okamura N, Yamaya K, Liu Q, et al. Circulating cytokines and hormones with immunosuppressive but neutrophil-priming potentials rise after endurance exercise in humans. European Journal of Applied Physiology. 2000; 81(4):281-7.
Taji Tabas A, Mogharnasi M. The effect of 10 week resistance exercise training on serum levels of nesfatin-1 and insulin resistance index in woman with type 2 diabetes. Iranian Journal of Diabetes and Metabolism. 2016; 14(3):179-88.
Haghshenas R, Jafari M, Ravasi A, Kordi M, Gilani N, Shariatzadeh M, et al. The effect of eight weeks endurance training and high-fat diet on appetite-regulating hormones in rat plasma. Iranian journal of basic medical sciences. 2014; 17(4):237.
Haghshenas R, Ravasi AA, Kordi MR, Hedayati M, Shabkhiz F, Shariatzadeh M. The effect of a 12-week endurance training on il-6, il-10 and nesfatin-1 plasma level of obese male rats. 2014.
Ghanbari Niaki A, Hosseini F, Rooadbari F, Rahmati Ahmadabad S, Rooadbari M. Effects of Aerobic Training, with or without Zizyphus Jujuba Water Extraction, on Fundus Nesfatin-1, ATP, HDL-C, and LDL-C Concentrations in Female Rats. Iranian Journal of Health and Physical activity. 2013; 4(1).
Ye J, Keller JN. Regulation of energy metabolism by inflammation: a feedback response in obesity and calorie restriction. Aging (Albany NY). 2010; 2(6):361.
Tofighi A, Mehrabani J, Khadivi SM. the effect of 8 week aerobic exercise on nesfatin-1 and acylated ghrelin in young obese men. 2014.
Ramanjaneya M, Chen J, Brown JE, Tripathi G, Hallschmid M, Patel S, et al. Identification of nesfatin-1 in human and murine adipose tissue: a novel depot-specific adipokine with increased levels in obesity. Endocrinology. 2010; 151(7):3169-80.
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