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Vol. 5 No. 1 (2017)

January 2017

Concurrent Hand and Penile Gangrene following Prolonged Warfarin Use; a Case Report

  • Fatemeh Mahdizadeh
  • Saeed Safari

Archives of Academic Emergency Medicine, Vol. 5 No. 1 (2017), 1 January 2017 , Page e71
https://doi.org/10.22037/aaem.v5i1.196 Published: 2017-06-21

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Abstract

Warfarin induced skin necrosis (WISN) is a rare but important side effect of warfarin. Early diagnosis may lessen the amount of permanent tissue damage and can prevent progression to full thickness skin necrosis. So, physicians should be aware of such a complication. Screening for protein C or S or anti-thrombin deficiencies, or presence of anti-phospholipid antibodies before beginning warfarin therapy, could be helpful to avoid high levels of international normalized ratio (INR). Here, we report a 54-year-old man who presented to the emergency department with acral and penile gangrene following prolonged use of warfarin.
Keywords:
  • Warfarin
  • penile diseases
  • gangrene
  • anticoagulants
  • necrosis
  • extremities
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How to Cite

1.
Mahdizadeh F, Safari S. Concurrent Hand and Penile Gangrene following Prolonged Warfarin Use; a Case Report. Arch Acad Emerg Med [Internet]. 2017 Jun. 21 [cited 2026 Jul. 7];5(1):e71. Available from: https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/196
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References

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Miura Y, Ardenghy M, Ramasastry S, Kovach R, Hochberg J. Coumadin necrosis of the skin: report of four patients. Annals of plastic surgery. 1996;37(3):332-7.

Khalid K. Warfarin-induced necrosis of the breast: case report. Journal of postgraduate medicine. 2003;50(4):268-9.

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Pourdeyhimi N, Bullard Z. Warfarin-induced skin necrosis. Hospital pharmacy. 2014;49(11):1044-8.

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