Concurrent Hand and Penile Gangrene following Prolonged Warfarin Use; a Case Report
学术急诊医学档案,
卷 5 编号 1 (2017),
1 一月 2017
,
第 e71 页
https://doi.org/10.22037/aaem.v5i1.196
摘要
Warfarin induced skin necrosis (WISN) is a rare but important side effect of warfarin. Early diagnosis may lessen the amount of permanent tissue damage and can prevent progression to full thickness skin necrosis. So, physicians should be aware of such a complication. Screening for protein C or S or anti-thrombin deficiencies, or presence of anti-phospholipid antibodies before beginning warfarin therapy, could be helpful to avoid high levels of international normalized ratio (INR). Here, we report a 54-year-old man who presented to the emergency department with acral and penile gangrene following prolonged use of warfarin.- Warfarin
- penile diseases
- gangrene
- anticoagulants
- necrosis
- extremities
##submission.howToCite##
参考
Kakagia D, Papanas N, Karadimas E, Polychronidis A. Warfarin-induced skin necrosis. Annals of dermatology. 2014;26(1):96-8.
Chan Y, Valenti D, Mansfield A, Stansby G. Warfarin induced skin necrosis. British Journal of Surgery. 2000;87(3):266-72.
Murad AA, Daly T, Mulligan N, Lenane P. Extensive warfarin-induced skin necrosis successfully treated with negative pressure wound therapy. BMJ case reports. 2014;2014:bcr2013203510.
Choudhary S, Madnani A, Singh A. Late onset Warfarin induced skin necrosis in human immunodeficiency virus infected patient with pulmonary tuberculosis. Indian journal of sexually transmitted diseases. 2013;34(1):47-9.
Kozac N, Schattner A. Warfarin-Induced Skin Necrosis. Journal of General Internal Medicine. 2014;29(1):248-9.
Alves D, Chen I. Warfarin-Induced Skin Necrosis. Hospital Physician. 2002;38(8):39-42.
Miura Y, Ardenghy M, Ramasastry S, Kovach R, Hochberg J. Coumadin necrosis of the skin: report of four patients. Annals of plastic surgery. 1996;37(3):332-7.
Khalid K. Warfarin-induced necrosis of the breast: case report. Journal of postgraduate medicine. 2003;50(4):268-9.
Nazarian R, Van Cott E, Zembowicz A, Duncan L. Warfarin-induced skin necrosis. Journal of the American Academy of Dermatology. 2009;61(2):325.
Pourdeyhimi N, Bullard Z. Warfarin-induced skin necrosis. Hospital pharmacy. 2014;49(11):1044-8.
- 摘要 ##plugins.themes.ojsPlusA.frontend.article.viewed##: 410 ##plugins.themes.ojsPlusA.frontend.article.times##
- PDF (English) ##plugins.themes.ojsPlusA.frontend.article.downloaded##: 176 ##plugins.themes.ojsPlusA.frontend.article.times##
- HTML (English) ##plugins.themes.ojsPlusA.frontend.article.downloaded##: 83 ##plugins.themes.ojsPlusA.frontend.article.times##
##plugins.themes.ojsPlusA.frontend.article.downloadstatastics##
##plugins.block.makeSubmission.linkLabel##
SJR
COPE
