20-Day Trend of Serum Potassium Changes in Bam Earthquake Victims with Crush Syndrome; a Cross-sectional Study
Archives of Academic Emergency Medicine,
Vol. 5 No. 1 (2017),
1 January 2017
,
Page e5
https://doi.org/10.22037/aaem.v5i1.108
Abstract
Introduction: Many of those who survive following an earthquake die in the next phase due to preventable and treatable medical conditions such as hyperkalemia. The present study aimed to evaluate the trend of potassium changes in crush syndrome patients of Bam earthquake. Methods: In this retrospective cross-sectional study, using the database of Bam earthquake victims, which were developed by Iranian Society of Nephrology following Bam earthquake, Iran, 2003, the 20-day trend of potassium changes in > 15 years old crush syndrome patients was evaluated. Results: 135 crush syndrome patients with the mean age of 29.9 ± 9.91 years were evaluated (56.3% male). Mean potassium concentration during the first 3 days of admission was 5.6 ± 1.3 mEq/L. On the day of admission, 43.1% (95% CI: 34.0 - 52.2) had normal potassium concentration, 3.4% (95% CI: 0.1 - 6.8) had hypokalemia, and 53.4% (44.3 - 62.6) had hyperkalemia. During 20-day follow-up, 62.3% (95% CI: 66.7-71.9) of the patients had normal potassium. While, 11.5% (95% CI: 9.7-13.3) had hypokalemia and 19.2% (95% CI: 17.0-21.5) had hyperkalemia. As the days of hospitalization increased, prevalence of hyperkalemia decreased while hypokalemia increased. On the 17th day 21.2% (95% CI: 2.2-39.9) had hypokalemia and 10.5% (95% CI: 0.1 – 24.7) had hyperkalemia. Conclusion: Findings of the present study showed that following urine alkalinization and fluid resuscitation, the prevalence of hyperkalemia reduced, but hypokalemia developed. It seems that the correction of serum potassium level should be accompanied by precise monitoring of intake and output of the patient and prescription of reasonable amount of intravenous fluid.- Rhabdomyolysis
- crush syndrome
- potassium
- water-electrolyte imbalance
- disaster victims
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References
Hosseini M, Safari S, Sharifi A, Amini M, Farokhi FR, Sanadgol H, et al. Wide spectrum of traumatic rhabdomyolysis in earthquake victims. Acta Med Iran. 2009;47(6):459-64.
Najafi I, Van Biesen W, Sharifi A, Hoseini M, Farokhi FR, Sanadgol H, et al. Early detection of patients at high risk for acute kidney injury during disasters: development of a scoring system based on the Bam earthquake experience. J Nephrol. 2008;21(5):776-82.
Tolouian R, Wild D, Lashkari MH, Najafi I. Oral alkalinizing solution as a potential prophylaxis against myoglobinuric acute renal failure: preliminary data from healthy volunteers. Nephrol Dial Transplant. 2005;20(6):1228-31.
Gonzalez D. Crush syndrome. Crit Care Med. 2005;33(1):S34-41.
Huerta-Alardin AL, Varon J, Marik PE. Bench-to-bedside review: rhabdomyolysis--an overview for clinicians. Crit care. 2005;9(2):158-69.
Smith J, Greaves I. Crush injury and crush syndrome: a review. J Trauma. 2003;54(5 Suppl):S226-30.
Erek E, Sever MS, Serdengecti K, Vanholder R, Akoglu E, Yavuz M, et al. An overview of morbidity and mortality in patients with acute renal failure due to crush syndrome: the Marmara earthquake experience. Nephrol Dial Transplant. 2002;17(1):33-40.
Vanholder R, van der Tol A, De Smet M, Hoste E, Koc M, Hussain A, et al. Earthquakes and crush syndrome casualties: lessons learned from the Kashmir disaster. Kidney Int. 2007;71(1):17-23.
Gunal AI, Celiker H, Dogukan A, Ozalp G, Kirciman E, Simsekli H, et al. Early and vigorous fluid resuscitation prevents acute renal failure in the crush victims of catastrophic earthquakes. J Am Soc Nephrol. 2004;15(7):1862-7.
He Q, Wang F, Li G, Chen X, Liao C, Zou Y, et al. Crush Syndrome and Acute Kidney Injury in the Wenchuan Earthquake. J Trauma Acute Care Surg. 2011;70(5):1213-8.
Oda J, Tanaka H, Yoshioka T, Iwai A, Yamamura H, Ishikawa K, et al. Analysis of 372 Patients with Crush Syndrome Caused by the Hanshin-Awaji Earthquake. J Trauma Acute Care Surg. 1997;42(3):470-6.
Alavi-Moghaddam M, Safari S, Najafi I, Hosseini M. Accuracy of urine dipstick in the detection of patients at risk for crush-induced rhabdomyolysis and acute kidney injury. Eur J Emerg Med. 2012;19(5):329-32.
Safari S, Najafi I, Hosseini M. Outcomes of fasciotomy in patients with crush-induced acute kidney injury after Bam earthquake. Iran J Kidney Dis. 2011;5(1):25-8.
Iraj N, Saeed S, Mostafa H, Houshang S, Ali S, Farin RF, et al. Prophylactic fluid therapy in crushed victims of Bam earthquake. Am J Emerg Med. 2011;29(7):738-42.
Najafi I, Safari S, Sharifi A, Sanadgol H, Hosseini M, Rashid-Farokhi F, et al. Practical strategies to reduce morbidity and mortality of natural catastrophes: a retrospective study based on Bam earthquake experience. Arch Iran Med. 2009;12(4):347-52.
Rajagopalan S. Crush injuries and the crush syndrome. Med J Armed Forces India. 2010;66(4):317-20.
Kasper D, Fauci A, Hauser S, Longo D, Jameson J, Loscalzo J. Harrison's Principles of Internal Medicine 19/E (Vol. 1 & Vol. 2): McGraw Hill Professional; 2015.
Safari S, Yousefifard M, Hashemi B, Baratloo A, Forouzanfar MM, Rahmati F, et al. The value of serum creatine kinase in predicting the risk of rhabdomyolysis-induced acute kidney injury: a systematic review and meta-analysis. Clin Exp Nephrol. 2016:1-9.
Safari S, Yousefifard M, Baikpour M, Rahimi-Movaghar V, Abiri S, Falaki M, et al. Validation of thoracic injury rule out criteria as a decision instrument for screening of chest radiography in blunt thoracic trauma. J Clin Orthop Trauma. 2016;[In press].
Shojaee M, Faridaalaee G, Yousefifard M, Yaseri M, Arhami Dolatabadi A, Sabzghabaei A, et al. New scoring system for intra-abdominal injury diagnosis after blunt trauma. Chin J Traumatol. 2014;17(1):19-24.
Hosseini M, Ghelichkhani P, Baikpour M, Tafakhori A, Asady H, Haji Ghanbari MJ, et al. Diagnostic Accuracy of Ultrasonography and Radiography in Detection of Pulmonary Contusion; a Systematic Review and Meta-Analysis. Emerg (Tehran). 2015;3(4):127-36.
Yousefifard M, Baikpour M, Ghelichkhani P, Asady H, Shahsavari Nia K, Moghadas Jafari A, et al. Screening Performance Characteristic of Ultrasonography and Radiography in Detection of Pleural Effusion; a Meta-Analysis. Emerg (Tehran). 2016;4(1):1-10.
Allister C. Cardiac arrest after crush injury. BMJ. 1983;287(6391):531-2.
Better OS. The crush syndrome revisited (1940-1990). Nephron. 1990;55(2):97-103.
Sever MS, Erek E, Vanholder R, Kantarci G, Yavuz M, Turkmen A, et al. Serum potassium in the crush syndrome victims of the Marmara disaster. Clin Nephrol. 2003;59(5):326-33.
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