Shahid Beheshti University of Medical Sciecnes
  • Register
  • Login

Regeneration, Reconstruction & Restoration (Triple R)

  • Home
  • Journal Info
    • About the Journal
    • Aims and Scope
    • Editorial Board
    • Indexing and Abstracting
    • Privacy Statement
    • Journal History
  • Issues
    • Current
    • Archives
  • Publication Ethics
  • Journal Policies
    • Licensing
    • Copyright
    • Archiving
    • Repository
    • Pre-Print
    • Reviewing Policy
    • Plagirism Checking
    • Using Artificial Intelligence (AI)
    • Article Processing Charge (APC)
  • Guidelines
    • Guidelines for Authors
    • Guidelines for Reviewers
    • Files for Submission
  • Submit
  • Contact Us
Advanced Search
  1. Home
  2. Archives
  3. Vol. 10 (2025)
  4. Case Report/ Case Series

Vol. 10 (2025)

Dey 2025

Salivary Duct Cyst of the Lower Labial Mucosa: A Rare Case Report and Literature Review Salivary Duct Cyst of the Lower Lip

  • Saede Atarbashi-Moghadam
  • Ali Lotfi
  • Sepehr Ghasemi
  • Mohammadreza Kashefi Baher

Regeneration, Reconstruction & Restoration (Triple R), Vol. 10 (2025), 1 Dey 2025
https://doi.org/10.22037/rrr.v10.51134 Published: 2025-12-21

  • View Article
  • Download
  • Cite
  • References
  • Statastics
  • Share

Abstract

Salivary duct cyst (SDC) is a rare reactive lesion of the salivary gland ducts and is infrequently reported in minor intraoral glands, particularly the lower lip. We describe a 49-year-old man with a painless, well-circumscribed submucosal swelling of the lower lip. Clinical findings suggested mucocele or salivary gland tumor, and excisional biopsy revealed a cyst lined by thin cuboidal epithelium adjacent to salivary gland lobules, confirming SDC. The lesion was completely removed, and no recurrence has been observed. Furthermore, a review of English-language literature from PubMed, Scopus, and Web of Science shows that intraoral SDCs typically affect middle-aged adults, demonstrate slight female predominance, and present as soft, mucosa-colored swellings with variable histopathologic patterns, including occasional epithelial metaplasia. Surgical excision remains the preferred management, with recurrence considered rare, although follow-up is recommended. This case underscores the need to include SDC in the differential diagnosis of atypical lip swellings.

Keywords:
  • Salivary Glands
  • Salivary Ducts
  • Salivary Gland Diseases
  • Mucocele
  • PDF

How to Cite

1.
Atarbashi-Moghadam S, Lotfi A, Ghasemi S, Kashefi Baher M. Salivary Duct Cyst of the Lower Labial Mucosa: A Rare Case Report and Literature Review: Salivary Duct Cyst of the Lower Lip. Regen Reconstr Restor [Internet]. 2025 Dec. 21 [cited 2026 Aug. 22];10. Available from: https://journals.sbmu.ac.ir/tripleR/article/view/51134
  • ACM
  • ACS
  • APA
  • ABNT
  • Chicago
  • Harvard
  • IEEE
  • MLA
  • Turabian
  • Vancouver
  • Endnote/Zotero/Mendeley (RIS)
  • BibTeX

References

1. Antoniades D, Epivatianos A, Markopoulos A, Kolokotronis A, Zaraboukas T. Coexistence of Mucous Retention Cyst and Basal Cell Adenoma Arising from the Lining Epithelium of the Cyst: Report of Two Cases. Medical Principles and Practice. 2009;18(3):248-52.

2. Stojanov IJ, Malik UA, Woo SB. Intraoral Salivary Duct Cyst: Clinical and Histopathologic Features of 177 Cases. Head Neck Pathol. 2017;11(4):469-76.

3. Jin YT, Hwang MJ, Chang JY, Chiang CP. Mucus retention cyst with oncocytic metaplasia of the epithelial lining. J Dent Sci. 2022;17(1):615-7.

4. Chi AC, Lambert PR, 3rd, Richardson MS, Neville BW. Oral mucoceles: a clinicopathologic review of 1,824 cases, including unusual variants. J Oral Maxillofac Surg. 2011;69(4):1086-93.

5. Eversole LR. Oral sialocysts. Arch Otolaryngol Head Neck Surg. 1987;113(1):51-6.

6. Misra SR, Priyadarshini S, Pati AR, Bhuyan SK, Panigrahi RG. Congenital mucous retention cyst of the anterior hard palate! The first case report. J Clin Diagn Res. 2014;8(10):Zd26-7.

7. Ide F, Ito Y, Watanabe J, Muramatsu T, Yamamoto H, Kikuchi K. Ectopic Salivary Duct Cyst in the Median Mandible: A Case Report with Radiological, Immunohistochemical and Genetic Studies. Int J Surg Pathol. 2025;33(5):1275-80.

8. Pantham H, Kumar NGR, Kumar AS, Sowmya M, Srikanth D. Intraoral salivary duct cyst – A rare case report with review of literature. SRM Journal of Research in Dental Sciences. 2024;15(4):236-9.

9. Kang FY, Lee YP, Sun A, Chiang CP. Salivary duct cyst of the upper lip. J Dent Sci. 2025;20(2):1306-8.

10. Tal H, Altini M, Lemmer J. Multiple mucous retention cysts of the oral mucosa. Oral Surg Oral Med Oral Pathol. 1984;58(6):692-5.

11. Nagar SR, Pandey NL, Bansal S, Desai RS. Intraoral salivary duct cyst: Report of a rare entity. J Oral Maxillofac Pathol. 2019;23(3):429-31.

12. Shih AN, Jin YT, Sun A, Chiang CP. Concurrent occurrence of a salivary duct cyst and two mucoceles in the lower lip. J Dent Sci. 2025;20(3):1950-2.

13. Chaves FN, Carvalho FS, Pereira KM, Costa FW. Salivary duct cyst in the upper lip: case report and review of the literature. Indian J Pathol Microbiol. 2013;56(2):163-5.

14. Tseng CH, Wang YP, Wu YH, Chang JY. Keratin debris-filled ruptured salivary duct cyst. J Formos Med Assoc. 2015;114(12):1291-2.

15. Lanzel EA, Pourian A, Sousa Melo SL, Brogden KA, Hellstein JW. Expression of membrane-bound mucins and p63 in distinguishing mucoepidermoid carcinoma from papillary cystadenoma. Head and neck pathology. 2016;10(4):521-6.

16. Begum B, Sekar R, Raja K, Stephen N. An Uncommon Salivary Gland Swelling- Parotid Duct Cyst and Its Management. Indian Journal of Otolaryngology and Head & Neck Surgery. 2024;76(1):1080-3.

17. De Las Casas LE, Bardales RH. Fine-needle aspiration cytology of mucous retention cyst of the tongue: distinction from other cystic lesions of the tongue. Diagn Cytopathol. 2000;22(5):308-12.

  • Abstract Viewed: 33 times
  • PDF Downloaded: 31 times

Download Statastics

  • Linkedin
  • Twitter
  • Facebook
  • Google Plus
  • Telegram

Developed By

Open Journal Systems

Information

  • For Readers
  • For Authors
  • For Librarians
  • Home
  • Archives
  • Submissions
  • About the Journal
  • Editorial Team
  • Contact

This work is licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International.

Powered by OJSPlus