RIFLE Criteria in Critically Ill Neonates with Acute Kidney Injury
Journal of Pediatric Nephrology,
Vol. 3 No. 1 (2015),
10 January 2015
,
Page 16-21
https://doi.org/10.22037/jpn.v3i1.7812
Abstract
Introduction: Diagnosis of neonatal acute kidney injury (AKI) is a difficult dilemma and there is no consensus in this regard. Based on RIFLE criteria the definition of ARF is changed lately in adult and pediatric groups. Studies to evaluate the RIFLE criteria in the definition of neonatal ARF have not been performed. The aim of this study was to determine prevalence of AKI based on old definition of ARF and RIFLE criteria separately.
Materials and Methods: This descriptive study was conducted on 904 critically ill neonates. The authors determined the RIFLE criteria for each neonate based on serum creatinine and urine output at the second day of admission. The RIFLE acronym stands for risk, injury, failure, loss of kidney function and end stage renal disease. Prevalence of AKI was determined based on old definition of ARF and RIFLE criteria separately.
Results: Based on RIFLE criteria, 22.5% of study group had normal renal function and 77.5% had AKI at the second day of admission. Among patients with AKI 43% met the risk, 51% the injury and about 6% the failure criterion. Based on old definition of ARF in neonates, the prevalence of ARF in our study group was 3.2%. There was a significant difference between AKI prevalence by RIFLE criteria and the former definition (P<0.001).
Conclusions: The RIFLE criterion is a simple tool for the detection and classification of AKI in NICUs.
Keywords: Acute Kidney Injury; Newborn Intensive Care Units; Critically Ill.
How to Cite
References
Stapleton FB, Jones DP, Green RS. Acute renal failure in neonates: Incidence, etiology and outcome. Pediatric Nephrology 1987;1(3):314-320.
Suhas M Nafday et al. In MG MacDonald, eds. Renal Disease –Avery’s Neonatology pathophysiology and management of newborn, 6th ed. Lippincott Williams and Wilkins. 2005;981-1065.
Gouyon J B, Guignard J P. Management of acute renal failure in newborns. Pediatr Nephrol 2000;14: 1037-1044.
Bellomo R, Ronco C, Kellum JA. The ADQI workgroup. Acute renal failure definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care 2004;8:R204–R212
Ravindra LM, John AK, Sudhir VS. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Critical Care 2007;11:31.
Anand SK. Acute renal failure in the neonate. Pediatr Clin North Am 1982;29: 791–800.
Aschinberg LC, Zeis PM, Hagerman JR, Vidyasagar D. Acute renal failure in the newborn. Crit Care Med 1977;5: 36–42.
Rahman N, Boineau FB, Lewy JE. Renal failure in the perinatal period. Clin Perinatol 1981;8:241–250.
Reimold EW, Don TD, Worthen HG. Renal failure during the first year of life. Pediatrics 1977;859: 987–994.
Griffen NK, McElnea J, Barratt TM. Acute renal failure in early life. Arch Dis Child 1976;51: 459–462.
Norman ME, Asadi FK. A prospective study of acute renal failure in the newborn infant. Pediatrics 1979;63:475–479.
Mathew OP, Jones AS, James E, Bland H, Groshong T. Neonatal renal failure: usefulness of diagnostic indices. Pediatrics 1980.65:57–60.
Ellis EN, Arnold WC. Use of urinary indexes in renal failure in the newborn. Am J Dis Child 1982;136: 615–617.
Chevalier RL, Campbell F, Norman A, Brenbridge AG. Prognostic factors in neonatal acute renal failure. Pediatrics 1984;74:265–272.
Norman Jones AS, James E, Bland H, Groshong T. Renal failure in the newborn.Clin Ped1979;18:286–290.
Brion LP, Bernstein J, Spitzer A. Kidney and urinary tract. In Neonatal-perinatal medicine: Diseases of the Fetus and Infant. Fanaroff AA, Martin RJ eds. St. Louis, Mosby-Year Book Inc., 1997, pp 1586.
Grylack L, Medani C, Hultzen C, Sivasubramanian K, Davitt MK, Jose P, Scanlon JW. Nonoliguric acute renal failure in the newborn. Am J Dis Child 1982;136:518–520.
Jayashree G, Dutta AK, Sarna MS, Saili A. Acute renal failure in asphyxiated newborns.Ind J Pediatr 1991; 28:19–23.
Ellis EN, Arnold WC. Use of urinary indices in renal failure in the newborn. Am J Dis Child 1982;136: 615–617.
Choker G. Gouyon J.B. Diagnosis of Acute Renal Failure in Very Preterm Infants. Biol Neonate 2004;86:212–216.
Akcan-Arikan A, Zappitelli M, Loftis LL. Modified RIFLE criteria in critically ill children with acute kidney injury. Kidney Int 2007;71:1028–1035.
Askenazi D, Griffin R, McGwin G. Acute kidney injury is independently associated with mortality in very low birthweight infants: a matched case–control analysis. Pediatr Nephrol 2009;24:991–997.
Askenazi DJ, Ambalavanan N, Goldestein S. Acute kidney injury in critically ill neonates. Pediatr Nephrol 2009;24:265-74.
Agras PI,Tarcan, Baskin E, Gürakan B, Saatci U. Acute Renal Failure in the Neonatal Period. Renal Failure 2004;26(3):305-309.
Subramanian S, Agarwal R, Deorari AK. Acute Renal Failure in Neonates. Indian Journal of Pediatrics 2008;75:385-391.
Andreoli SP. Acute renal failure in the newborn. Semin Perinatol 2004;28:112–123.
Perez Valdivieso J.R, Bes-Rastrollo M, Monedero P. Evaluation of the prognostic value of the risk, injury, failure, loss and end-stage renal failure (RIFLE) criteria for acute kidney injury. Nephrology 2008;13(5):361-366.
Ricci Z, Cruz D, Ronco C. The RIFLE criteria and mortality in acute kidney injury: A systematic review. Kidney International 2008;73,538–546.
Plo¨tz BF, Bouma AB, Wijk EJ. Pediatric acute kidney injury in the ICU:an independent evaluation of pRIFLE criteria. Intensive Care Med 2008;34:1713–1717.
Hooman N. Acute Kidney Injury in Iranian Children -What Do We Know About It? - Part 2. J Ped. Nephrology 2014;2(3):98-103.
Moghtaderi M, Yaghmaii B, Allahwerdi B, et al. Acute Kidney Injury in Children with Acute Gastroenteritis. J Ped. Nephrology 2014;2(2):76-78.
Schneider J, Khemani R, Grushkin C. Serum creatinine as stratified in the RIFLE score for acute kidney injury is associated with mortality and length of stay for children in the pediatric intensive care unit. Crit Care Med 2010;38(3):933-939.
Ferraz RRN,de Deus RB. Incidence of acute renal failure in the neonatal intensive care unit of a hospital in São Paulo [Portuguese]. Acta Paulista de Enfermagem 2009;22:497-500.
Mathur NB, Himanshu S. Agarwal, Arti Maria. Acute Renal Failure in Neonatal Sepsis. Indian Journal of Pediatrics 2006;199-50273.
Esfandiar N, Mohkam M, Afjeii A, et al. Prognostic Factors and Mortality Rate in Neonates with Acute Renal Injury in NICU. J Ped. Nephrology 2013 July;1(1):32-36.
- Abstract Viewed: 847 times
- PDF Downloaded: 4841 times