A case report of MIS-C secondary to surgical site infection MIS-C presenting as a complication of surgical site infection after orthopedic surgery
Journal of Pediatric Nephrology,
Vol. 13 No. 1 (2025),
12 May 2026
https://doi.org/10.22037/jpn.v13i1.50713
Abstract
Background: Multisystem inflammatory syndrome in children is a serious state in which a patient (typically infected with SARS-CoV-2) manifests symptoms of multi-organ failure a few weeks after exposure due to broad adaptive and innate immune activation.
Case presentation: A 13-year-old boy with history of multiple trauma and subsequent lower limb fracture followed by orthopedic surgery, presented to the emergency department with surgical site infection (SSI). After 6 days of admission, patient represented symptoms of multisystem inflammatory syndrome including renal shutdown and blood creatinine rise. As a result, hemodialysis was performed. Patient's blood culture was negative and all of the similar clinical situations (like sepsis, toxic shock, etc.) was ruled out during orthopedic surgery and infectious disease specialties' consultations.
Conclusion: MIS-C is a syndrome which can be emerged not only secondary to SARS-CoV-2 infection, but also can be developed by surgical site infections secondary to orthopedic surgeries. Regular organ function monitoring in patients with SSI complications can be very beneficial in early diagnosis and preventing complications.
- Multisystem inflammatory syndrome
- MIS-c
- Surgical wound infection
- SSI
- multiple trauma
- lower limb fracture
How to Cite
References
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