Effect of Vitamin E Therapy on Children With Renal Stones
Journal of Pediatric Nephrology,
Vol. 12 No. 1 (2024),
10 April 2025
https://doi.org/10.22037/jpn.v12i1.48250
Abstract
Background and Aim: Urinary system stones, including kidney stones, are common diseases
of the kidney and urinary tract that have increased over time. The treatment of these patients,
especially in children, is of great importance. This study evaluated the effect of vitamin E on
the treatment of children with kidney stones.
Methods: This double-blind, randomized controlled trial (RCT) was conducted on children
between the ages of 2 and 18 years with a diagnosis of kidney stones. The samples were
randomly divided into two groups: The intervention group, which received vitamin E in
addition to standard treatment, and the control group, which received standard treatment.
This division was blinded to the evaluator and the patients. Information about the condition
of the stones before and after treatment was obtained from two sources and compared using
SPSS statistical software.
Results: The mean age (P=0.595) and frequency distribution of gender (P=0.685) showed
no statistically significant difference between the two groups. The mean number of stones
before treatment in the intervention group was 3.04±1.87, while in the control group, they
were 3.22±2.01, indicating no significant difference according to the independent t-test. After
treatment, values were 1.15±1.3 in the intervention group and 2.34±1.75 in the control group.
The mean size of the largest stone in the intervention group before treatment was 0.09±0.34
cm, and after treatment, it was 0.18±0.07 cm (P=0.964). In the control group, the size of the
largest stone before treatment was 0.10±0.32 cm, and after treatment, it increased to 0.25±0.1
cm, which was significantly smaller in the intervention group based on the independent t-test.
Conclusion: The use of vitamin E can reduce the size and number of kidney stones in
children.
- Vitamin E
- Kidney stones
- Children
- Treatment
How to Cite
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