Severe Pancreatitis After Renal Transplantation Due to Disseminated Cytomegalovirus Infection: A Case Report Pancreatitis After Renal Transplantation
Journal of Pediatric Nephrology,
Vol. 12 No. 1 (2024),
10 April 2025
https://doi.org/10.22037/jpn.v12i1.48224
Abstract
Background and Aim: Cytomegalovirus (CMV) infection is considered one of the most
common opportunistic infections and also a common cause of morbidity and mortality
among patients receiving renal transplantation. Pancreatitis is a rare complication of CMV
infection in renal transplant recipients, which can lead to death. Here,
Case Presentation: we presented a 10-year-old boy who underwent a nonrelative living
donor renal transplantation and was admitted due to early graft dysfunction two months
after transplantation. Diagnostic tests for modalities showed CMV infection. The patient was
treated with ganciclovir; however, he developed seizures and acute abdominal pain one week
later. The brain MRI revealed increased signal intensity in the cortex and subcortex of the
parieto-occipital lobe. Serum laboratory tests showed elevated levels of amylase and lipase.
The patient was treated for CMV infection and pancreatitis.
Conclusion: Finally, the patient died due to multi-organ failure caused by disseminated
CMV infection two weeks after admission. These findings suggest that disseminated CMV
infection and pancreatitis may occur after renal transplantation, with a high mortality rate.
- Renal transplantation
- Cytomegalovirus
- Severe pancreatitis
How to Cite
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