Investigating Hypovitaminosis D and Childhood Nephrotic Syndrome vitamin D and Nephrotic Syndrome
Journal of Pediatric Nephrology,
Vol. 13 (2025),
12 May 2026
https://doi.org/10.22037/jpn.v13i1.47762
Abstract
This letter aims to bring focus to the important
connection between vitamin D
deficiency and nephrotic syndrome (NS)
in children, an area deserving greater clinical
and investigative priority [1]. Pediatric
NS, characterized by significant proteinuria, hypoalbuminemia,
and edema, continues to be a major contributor
to illness among children. Although corticosteroid
therapy is the primary treatment, frequent disease flares
and steroid dependence often worsen long-term prognosis,
highlighting the importance of managing associated
treatable conditions.
- clinical implications
- research recommendations
- Prevalence data
How to Cite
References
[1] Nandi S. Investigating Hypovitaminosis D and Childhood
Nephrotic Syndrome: An Observational Study to Find Subjects
in Need of Attention. J Pediatr Nephrol. 2023; 11(4):203-
7. [Link]
[2] Selewski DT, Chen A, Shatat IF, Pais P, Greenbaum LA,
Geier P, et al. Vitamin D in incident nephrotic syndrome: A
Midwest Pediatric Nephrology Consortium study. Pediatr
Nephrol. 2016; 31(3):465-72. [DOI:10.1007/s00467-015-3236-x]
[PMID] [PMCID]
[3] Chun RF, Shieh A, Gottlieb C, Yacoubian V, Wang J,
Hewison M, et al. Vitamin D binding protein and the biological
activity of vitamin D. Front Endocrinol. 2019; 10:718.
[DOI:10.3389/fendo.2019.00718] [PMID] [PMCID]
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