The Results of Urine Toxicology Tests in Children With Drug Abuse Poisoning in Loghman Hakim Hospital in 2021
Journal of Pediatric Nephrology,
Vol. 12 No. 1 (2024),
10 April 2025
https://doi.org/10.22037/jpn.v12i1.46681
Abstract
Background and Aim: Correct and rapid diagnosis and timely treatment of acute poisoning
are of great importance, mainly in legally crucial drugs of abuse poisoning. Urine drug
toxicology (UDT) is an available, rapid, and cheap diagnostic tool. This study aims to
evaluate the results of this study in children with acute poisoning.
Methods: In this prospective descriptive cross-sectional study conducted on the urine
toxicology results of children admitted to Loghman-Hakim Hospital due to poisoning with
opioids and cannabis in 2021, UDT was performed for all patients. Demographic data, type,
method and time of poisoning, time of urine sample collection, urine pH and specific gravity
(SG), and urine toxicology results were collected and statically analyzed using SPSS version
26.
Results: A total of 137 children were evaluated. The mean age was 4.11±3.45 years, and
49.6% were boys. UDTs were positive in 106 of 137 patients (77.4%). The most common
poisoning was methadone (61.32%) followed by opium (19.71%). No significant statistical
difference was observed between the time of taking the urine sample as well as the type, pH,
and specific gravity (SG) (P>0.05). Of the 84 methadone-poisoned patients, 74 (88%) tested
positive for UDT. The positive results for opium, cannabis, and buprenorphine were 77.77%,
33.33%, and 50%, respectively.
Conclusion: In our study, methadone was the most common poisoning, with urine toxicology
showing a positive result in 88% of cases.
- Urine toxicology test
- Methadone
- Opium
How to Cite
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