Investigating the Acute Effects of Hemodialysis on Hemodynamic and Electrocardiographic Parameters Hemodynamic and EKG Changes in HD
Journal of Pediatric Nephrology,
Vol. 11 No. 4 (2023),
5 Bahman 2025
https://doi.org/10.22037/jpn.v11i4.45100
Abstract
Background and Aim: Changes in electrocardiographic parameters are reported after
hemodialysis (HD). This study determines the alternations in electrocardiographic parameters,
hemodynamics, and body weight post-HD.
Methods: Electrocardiography was evaluated pre- and post-dialysis in 20 patients (55%
males) aged 16.25±6.25 years. Changes in electrocardiographic parameters were compared
considering changes in weight (post-dialysis and between dialysis sessions), blood pressure
(BP) indices, and the occurrence of intra-dialysis hypotension (IDH).
Results: A significant decrease was observed in weight, systolic, diastolic, and mean arterial
BPs post-dialysis (P<0.05, for all). No substantial changes in durations of PR interval, QT
interval corrected for heart rate, and QRS complex, as well as QT dispersion, were found
post-dialysis (P>0.05 for all). Hemodynamic and electrocardiographic alternations were not
significantly different between cases with adequate versus inadequate weight gain (P>0.05
for all). Meanwhile, dialysis-induced ventricular strain patterns (ST-T segment changes) were
found in 20% of patients, including three cases with inadequate weight gain inter-dialysis. In
one case, electrocardiographic findings of hyperkalemia resolved post-dialysis. Whereas, the
left ventricular strain pattern appeared in one other case.
Conclusion: HD is associated with significant acute changes in systolic and diastolic BP and
mean arterial pressure (MAP). These changes, if repeated frequently, can result in myocardial
ischemia and infarction. HD protects the heart against hyperkalemia, and thereby arrhythmia;
however, it causes ventricular strain patterns, which a predictive of adverse cardiovascular
outcomes. Evaluating the long-term complications of hemodynamic and electrocardiogram
changes in pediatric HD cases is suggested.
- Child
- Hemodialysis (HD)
- Hemodynamic changes
- Electrocardiography
How to Cite
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