Clinical Manifestations, Microbial Agents, and Types of Infection in Children With Urinary Tract Infection Urinary Tract Infection in Children
Journal of Pediatric Nephrology,
Vol. 10 No. 3 (2022),
12 December 2022
Background and Aim: Urinary Tract Infection (UTI) is common in children. This study
aims to evaluate demographic characteristics, etiologies, and clinical presentations of UTI
Methods: A cross-sectional retrospective study was conducted to investigate the available
data of the children with UTI referred to the nephrology clinic of a tertiary academic children’s
hospital from September 2002- 2016. Patients aged 0-18 years were included in the study.
Results: A total of 1245 cases, including 1084 girls (87.06%) and 161 boys (12.94%) were
included in the study. The age of patients at the first presentation was 35.43±34.94 months.
Fever was the most common manifestation (60.1%). The most and least cases of UTI were
reported in children aged 2-24 months (49.7%) and over 10 years old (2.9%), respectively.
The most common pathogens were E. coli, Klebsiella, Staphylococcus, Enterobacter,
Proteus, and Enterococcus species, respectively. The frequency of infection with E. coli in
girls was significantly higher than in boys (P=0001), while infection with Staphylococcus
and Proteus species was higher in boys (P=0.0001 and 0.002, respectively). The incidence
of pyelonephritis decreased with age. Furthermore, febrile UTIs were as common in boys as
in girls (P=0.42).
Conclusion: The prevalence of UTI is significantly higher in girls, and the frequency of UTI
varies according to age, reaching its peak in the first year of life, and the lowest frequency in
children over 10 years of age. Moreover, pyelonephritis is more common in younger children
(infants 2-24 months). Gender is a crucial factor in terms of pathogens.
- Urinary tract infections (UTI)
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