The Relationship Between the Renal Resistive Index and End Organ Damage Parameters in Hypertensive Pediatric Patients Resistivity Index and End Organ Damage Parameters
Journal of Pediatric Nephrology,
Vol. 10 No. 3 (2022),
12 December 2022
,
Page 117-122
https://doi.org/10.22037/jpn.v10i3.38803
Abstract
Background and Aim: This study aimed to investigate the strength of the relationship
between renal resistive index with left ventricular mass index, microalbuminuria, and
retinopathy to find a predictive value of the renal resistive index in early detection of
end-organ damage.
Methods: Pediatric patients diagnosed with hypertension were included in this study between
January 2020 and January 2022.
Results: A total of 41 consecutive patients who were never treated for essential hypertension
were included in this study. Microalbuminuria was detected in 10 patients (24%).
Retinopathy was detected in only 2 patients (4.9%). Echocardiographic data were available
in 25 patients. The mean left ventricular mass index was 30±10 (17-53 g/m2.7). Three male
patients (12%) had left ventricular hypertrophy but none of the females had left ventricular
hypertrophy. We categorized the patients into two groups according to the presence of
microalbuminuria and compared the two groups. The value of the renal resistive index in the
microalbuminuric group was significantly higher than in the nonalbuminuric group (0.8±0.2
vs. 0.6±0.2, P=0.047). We found a positive correlation between renal resistive index and
urine microalbumin (r=0.636, P=0.014). In regression analysis, higher resistive index values
were independently associated with microalbuminuria but not left ventricular hypertrophy.
(OR=-0.633, 95% CI 24.4-187.2, P=0.015)
Conclusion: To our knowledge, this is the first study to analyze the correlation of RI with
microalbuminuria in hypertensive children. We found a significantly higher resistive index
in patients with microalbuminuria; we also found a correlation between these variables.
This shows that this finding and an abnormal resistive index can be used as early signs of
hypertension.
- Hypertension
- Renal resistive index
- albuminuria
- Left ventricular hypertrophy
- Retinopathy
How to Cite
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