Half Saline or Normal Saline Maintenance Intravenous Fluid Therapy in Children Intravenous Fluid Therapy in Children
Journal of Pediatric Nephrology,
Vol. 10 No. 1 (2022),
20 April 2022
Background and Aim: Electrolyte disorders in hospitalized children have several causes.
One of the most important and common causes is using inappropriate maintenance
intravenous fluids. This study aimed to investigate the effect and type of maintenance of
intravenous fluids on the incidence of electrolyte disturbance in hospitalized children.
Methods: This research is a prospective cohort study. Non-surgical hospitalized children
were divided into two groups based on the type of intravenous fluid received (normal saline
[0.9% NaCl] or half saline [0.45% NaCl]). After matching two groups in terms of age and
gender, the incidence of electrolyte disturbances (sodium and potassium) was evaluated in the
two groups on the second and third days of the study.
Results: A total of 163 patients were included in this study. About 55.5% of the children were
boys, and 44.5% were girls. The Mean±SD age of the children was 48.42±36.35 months, and
their mean weight was 19.49±10.88 kg. Also, 50.6% of patients were in the half saline group
and 49.4% in the normal saline group. Initially, serum sodium and potassium levels were
normal in both groups. On the second and third days of the study, the incidence of serum
sodium and potassium disorders was higher in patients who received half saline fluid, but this
higher incidence was not statistically significant (P>0.05).
Conclusion: There is no significant difference between normal saline and half saline in
terms of electrolyte disturbance if the patient’s clinical condition is judged correctly and an
appropriate volume of fluids is prescribed.
- Fluid therapy
- Child, Electrolytes
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