The Relationship Between Prenatal Hydronephrosis and Vesicoureteral Reflux in Children With a History of Prenatal Hydronephrosis in the Third Trimester of Pregnancy
Journal of Pediatric Nephrology,
Vol. 10 No. 1 (2022),
20 April 2022
,
Page 17-22
https://doi.org/10.22037/jpn.v10i1.36303
Abstract
Background and Aim: Prenatal hydronephrosis is found in 1%-5% of pregnancies. Without
well-timed diagnosis and treatment, it can lead to irreversible outcomes. Because little
information is available on the indication of Vesicoureteral Reflux (VUR) regarding the
antenatal diameter of the kidney pelvis, the current study aimed to determine the association
between prenatal hydronephrosis and the VUR.
Methods: This cross-sectional study was conducted from 2011 to 2016 on 200 neonates
with hydronephrosis detected in fetal life ultrasounds in the third trimester of pregnancy.
We assessed the prenatal and postnatal kidney ultrasonography of 400 kidneys and Voiding
Cystourethrogram (VCUG). We employed the Spearman correlation coefficient for
determining the association between study variables. The obtained data were analyzed using
SPSS 16.0 software at a significance level of less than 0.05.
Results: Of 200 infants, 71.5% were males and 28.5% were females. No significant
relationship was found between the degree of antenatal hydronephrosis and the VCUG
severity (r=0.098, P=0.106). Despite antenatal hydronephrosis, the degree of postnatal
hydronephrosis and the VCUG severity was correlated (r= 0.255, P=0.001).
Conclusion: There is no correlation between the severity of fetal hydronephrosis and VUR
severity or the presence of a greater correlation between postnatal hydronephrosis and
degree of VUR. Thus in cases of mild prenatal hydronephrosis, we suggest urinary tract
ultrasonography three to seven days after birth and then cystography if postnatal sonography
showed moderate or severe or progressive hydronephrosis.
- Hydronephrosis
- Pyonephrosis
- Congenital
- Urinary tract infection
- Child
- Vesicoureteral reflux
- Cystography
How to Cite
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