Anaplastic Wilms’ Tumor Mimicking a Rhabdoid Tumor: A Diagnostic Challenge Wilms’ Tumor Mimicking a Rhabdoid Tumor
Journal of Pediatric Nephrology,
Vol. 9 No. 3 (2021),
https://doi.org/10.22037/jpn.v9i3.35043
Abstract
Rhabdoid tumor of the kidney (RTK) mimics other renal tumorshistologically, but a rhabdoid tumor mimicking an anaplastic Wilms’
tumor has been rarely reported. Wilms’ tumor classically comprises
three histological components, including a blastema, epithel
ium, and stroma. The degree of maturation of these components makes the
histological appearance of this tumor unique. Anaplasia is defined by
the presence of extreme nuclear and mitotic atypia. Most of these
lesions can be differentiated on the basis of light microscopic
histological investigations. Herein we report a case of pediatric
anaplastic Wilms’ tumor that was difficult to differentiate from a mesenchymal lesion histologically.
The application of immunohistochemistry and extensive sampling of the lesion was critical for accurate diagnosis.
Keywords:
Wilm’s Tumor; Child; Rhabdoid Tumor.
- Wilm’s Tumor
- Child
- Rhabdoid Tumor
How to Cite
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