Kidney Size Assessment in Children with Severe Acute Malnutrition Under 5 Years of Age: A Comparative Stud Kidney Size in Severe Acute Malnutrition
Journal of Pediatric Nephrology,
Vol. 9 No. 3 (2021),
4 September 2021
,
Page 1-7
https://doi.org/10.22037/jpn.v9i3.34122
Abstract
Background and Aim: Malnutrition is a common disorder worldwide. Growth of visceral organs is affected by various factors including nutrition. Kidney size is an important parameter to assess renal growth. Kidney size in malnourished children is not well studied. We compared kidney size between severe acute malnourished (SAM) and normal children.
Methods: This prospective case control study was carried out at a tertiary care center in North India. Children with SAM (n=124) were enrolled as cases and 86 age and sex matched healthy children were enrolled as controls. All children were subjected to anthropometric and sonographic kidney size measurement. Various renal size parameters were compared between cases and controls. Linear correlation coefficients of kidney dimensions with anthropometric parameters were derived. P-values <0.05 were considered significant.
Results: The kidney length was significantly lower in malnourished cases compared to healthy controls. There was no difference in renal width and combined kidney volume (CKV) between the two groups. However, renal depth, combined relative kidney volume, CKV/body height ratio, and CKV/BSA ratio were significantly higher in malnourished child compared to healthy controls. Kidney size parameters (kidney length, width, depth, CKV) had significant correlations with anthropometric measurements in both groups but the correlations were stronger in healthy controls compared to malnourished children.
Conclusion: Malnourished children had a significantly smaller kidney length. This point should be remembered while evaluating kidney size in these children to avoid unnecessary invasive investigations.
- Malnutrition
- Child
- Kidney Size
- Ultrasonography
How to Cite
References
Ece A, Gozu A, Bukte Y, Tutanc M, Kocamaz H. The effect of malnutrition on kidney size in children. Pediatr Nephrol 2007;22:857–863
Kim JH, Kim MJ, Lim SH, Kim J, Lee MJ. Length and volume of morphologically normal kidneys in Korean children: ultrasound measurement and estimation using body size. Korean J Radiol 2013;14(4):677-82.
Hoy WE, Douglas-Denton RN, Hughson MD, Cass A, Johnson K, Bertram JF.A stereological study of glomerular number and volume: Preliminary findings in a multiracial study of kidneys at autopsy. Kidney International 2003;83:S31-S37.
Brenner BM, Mackenzie HS. Nephron mass as a risk factor for progression of renal disease. Kidney IntSuppl 1997;63:S124-S127.
Singh GR, Hoy WE. Kidney volume, blood pressure, and albuminuria: findings in an Australian Aboriginal community. Am J Kidney Dis 2004;43:254-259.
Otiv AS, Mehta K, Ali U, Nadkarni M. Sonographic measurement of renal size in normal Indian children. Indian Pediatr 2012;49:533-536.
Dixit PK, Sahai SB, Rath B, Garg A, Chowdhary V.Norms for renal parenchymal volume in Indian children. Indian Pediatr. 1994;31:1059-64.
Mathur S, Chandra J, Mittal KP, Mittal SK, Khurana A.Sonographic assessment of renal length in Indian children. Indian J Pediatr 1996;63:553-60.
Ganesh R, Vasanthi T, Lalitha J, Rajkumar J, Muralinath S. Correlation of renal length with somatic variables in Indian children. Indian J Pediatr 2010;77:326-8.
WHO Child Growth Standards and the Identification of Severe Acute Malnutrition in Infants and Children: A Joint Statement by the World Health Organization and the United Nations Children’s Fund. Geneva: World Health Organization; 2009. English. Available from: https://www.ncbi.nlm.nih.gov/books/NBK200776/
Du Bois D, Du Bois EF. A formula to estimate the approximate surface area if height and weight be known. 1916. Nutrition 1989;5(5):303-313.
Singh R, Mittal SK. Malnutrition in Children. In: Sachdeva A, Dutta AK, editor. Advances in Paediatrics 2nd edition. New Delhi: Jaypee Brothers Medical Publishers (P) Ltd; 2012. p1303-1317.
International Institute for Population Sciences, Nutrition in India. Available from: http://rchiips.org/NFHS/nutrition_report_for_website_18sep09.pdf [Accessed 2 April 2014]
Morrison EY, Alleyne GA. Malnutrition, kidney size and composition. Arch Latinoam Nutr 1976;26:7-14.
Mishra K, Datta V, Aarushi A, Kaur Narula M, Iyer RS, Nangia S. The Association between Weight for Gestational Age and Kidney Volume: A Study in Newborns in India. Iran J Pediatr. 2014;24(1):93–99.
Giapros V, Drougia A, Hotoura E, Argyropoulou M, Papadopoulou F, Andronikou S. Kidney growth in twin children born small for gestational age. Nephrol Dial Transplant. 2010;25:3548-3554.
Schmidt IM, Main KM, Damgaard IN, Mau C, Haavisto AM, Chellakooty M, et al. Kidney growth in 717 healthy children aged 0-18 months:a longitudinal cohartstudy. Pediatr Nephrol 2004;19:992-1003.
Pantoja-Zuzuarregui J, Mallios R, Murphy J. The effect of obesity on kidney length in a healthy pediatric population. Pediatr Nephrol 2009;24:2023–2027
Kadioglu A. Renal measurements, including length, parenchymal thickness, and medullary pyramid thickness, in healthy children: what are the normative ultrasound values? Am J Roentgenol 2010;194:509–515
Scott JE, Hunter EW, Lee RE, Matthews JN. Ultrasound measurement of renal size in newborn infants. Arch Dis Child 1990;65:361-364.
Dinkel E, Ertel M, Dittrich M, Peters H, Berres M, Schulte-Wissermann H. Kidney size in childhood. Sonographical growth charts for kidney length and volume. Pediatr Radiol 1985;15:38–43.
Eze CU, Agwu KK, Ezeasor DN, Agwuna KK, Aronu AE, Mba EI. Sonographic biometry of normal kidney dimesions among school-age children in Nsukka, Southeast Nigeria. West Indian Med J 2014;63(1)46-53.
De Vries L, Levene MI. Measurement of renal size in preterm and term infants by real-time ultrasound. Arch Dis Child 1983;58:145-147.
Schmidt IM, Molgaard C, Main KM, Michaelsen KF. Effect of gender and lean body mass on kidney size in healthy 10-year-old children. Pediatr Nephrol 2001;16:366-370
Haugstvedt S, Lundberg J. Kidney size in normal children measured by sonography. Scand J Urol Nephrol 1980;14:251-5.
Kim BW, Song MK, Chung S, Kim KS. Evaluation of kidney size in children: a pilot study of renal length as a surrogate of organ growth. Korean J Pediatr. 2012;55(2):54–57. doi:10.3345/kjp.2012.55.2.5.
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