Cover of Journal of

Vol. 6 No. 1 (2018)

Vancomycin Induced Eosinophilic Peritonitis, A Case Report

Journal of Pediatric Nephrology, Vol. 6 No. 1 (2018), 4 May 2018 , Page 1-3
https://doi.org/10.22037/jpn.v6i1.20914

Abstract

Drug induced peritonitis is a rare but important complication of CAPD. Hereby, we report a case that developed eosinophilic peritonitis during intraperitoneal administration of vancomycin. With a suspicion of vancomycin-induced eosinophilic peritonitis, vancomycin was discontinued. Antihistamine started and the PD effluent two days after stopping the drug revealed a WBC count of 85/µl (10% Eosinophil, 71% Lymphocytes). Systemic signs improved dramatically in less than a week. In conclusion, drug induced peritonitis should be considered in different diagnosis of each patient on CAPD before considering administering another new antibiotic.

Keywords: Vancomycin; Peritonitis; Allergy and Immunology; Child. 

Keywords:
  • Vancomycin
  • Peritonitis
  • Allergy and Immunology

How to Cite

1.
Hooman N, Jahangiry F, Asdaghi M, Ghafari L. Vancomycin Induced Eosinophilic Peritonitis, A Case Report. J Ped Nephrol [Internet]. 2018 May 4 [cited 2026 Jul. 8];6(1):1-3. Available from: https://journals.sbmu.ac.ir/jpn/article/view/20914

References

Hooman N, Esfahani ST, Mohkam M, et al. The outcome of Iranian children on continuous ambulatory peritoneal dialysis: the first report of Iranian National Registry. Arch Iran Med. 2009 Jan;12(1):24-8. PubMed PMID: 19111025.,

Jahangiri F, Hooman N, Khaleghnejad-Tabari N. Surgical Outcome of Peritoneal Dialysis Catheter Insertion in Pediatric Patients: An Experience in Iran, Iran J Pediatr. 2017 ;27(5):e9728.doi: 10.5812/ijp.9728.

Mehrazma M, Amini-Alavijeh Z, Hooman N. Prognostic value of dialysis effluent leukocyte count in children on peritoneal dialysis with peritonitis. Iran J Kidney Dis. 2012 Mar;6(2):114-8. PubMed PMID: 22388609.

Hooman N, Madani A, Sharifian Dorcheh M, et al. Fungal peritonitis in Iranian children on continuous ambulatory peritoneal dialysis: a national experience. Iran J Kidney Dis. 2007 Jul;1(1):29-33. PubMed PMID: 19357441.

Lee S, Schoen I. Eosinophilia of peritoneal fluid and peripheral blood associated with chronic peritoneal dialysis. Am J Clin Pathol. 1967 May;47(5):638-40. PubMed PMID: 6022995.

Oh SY, Kim H, Kang JM, et al. Eosinophilic peritonitis in a patient with continuous ambulatory peritoneal dialysis (CAPD). Korean J Intern Med. 2004 Jun;19(2):121-3. PubMed PMID: 15366644; PubMed Central PMCID: PMC4531584.

Sligh JM, Gottlieb SJ, Domoto DT, Slavin RG. Characterization of eosinophils in a continuous ambulatory peritoneal dialysis patient with eosinophilic peritonitis. Int Arch Allergy Appl Immunol. 1991;95(2-3):174-7. PubMed PMID: 1937918.

Tang S, Lo CY, Lo WK, Chan TM. Resolution of eosinophilic peritonitis with ketotifen. Am J Kidney Dis. 1997 Sep;30(3):433-6. PubMed PMID: 9292574.

Wong PN, Mak SK, Lee KF, Fung LH, Wong AK. A prospective study of vancomycin-(Vancoled-)induced chemical peritonitis in CAPD patients. Perit Dial Int. 1997 Mar-Apr;17(2):202-4. PubMed PMID: 9159846.]

Freiman JP, Graham DJ, Reed TG, McGoodwin EB. Chemical peritonitis following the intraperitoneal administration of vancomycin. Perit Dial Int. 1992;12(1):57-60. PubMed PMID: 1543783.

Wang AY, Li PK, Lai KN. Comparison of intraperitoneal administration of two preparations of vancomycin in causing chemical peritonitis. Perit Dial Int. 1996 Mar-Apr;16(2):172-4. PubMed PMID: 9147552.

Perez Fontan M, Rodriguez-Carmona A, Galed I, Iglesias P, Villaverde P, Garcia-Ureta E. Incidence and significance of peritoneal eosinophilia during peritoneal dialysisrelated peritonitis. Perit Dial Int 2003; 23:460–4.

Deweese R, Slavens J, Barua A, Sutton J. Vancomycin-induced eosinophilic peritonitis. Am J Health Syst Pharm. 2016 May 1;73(9):e243-6. doi:10.2146/ajhp150376. PubMed PMID: 27099331.

Rosner MH, Chhatkuli B. Vancomycin-related eosinophilic peritonitis. Perit Dial Int. 2010 Nov-Dec;30(6):650-2. doi: 10.3747/pdi.2010.00062. PubMed PMID: 21148058.

Freitas C, Rodrigues A, Carvalho MJ, Cabrita A. Chemical peritonitis in a patient treated with icodextrin and intraperitoneal vancomycin. Nefrologia. 2011;31(5):625-6. doi: 10.3265/Nefrologia.pre2011.Jun.10989. English, Spanish. PubMed PMID: 21959743.

Ghafari L, Hooman N, jahangriry F, Vancomycin induced peritonitis-A case report. J Ped. Nephrology 2013 Nov. Supplement 1.http://journals.sbmu.ac.ir/jpn

  • Abstract Viewed: 339 times
  • PDF Downloaded: 306 times

Download Statastics

Developed By

Open Journal Systems

Information