Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Misdiagnosed as Recurrent Urinary Tract Infection
Journal of Pediatric Nephrology,
Vol. 4 No. 3 (2016),
22 December 2016
,
Page 116-118
https://doi.org/10.22037/jpn.v4i3.11759
Abstract
Recurrent fever is common in children and specific infections account for the fever in most cases. PFAPA is not an uncommon cause of periodic fever during childhood. On the other hand, in patients with vesicoureteral reflux (VUR), urinary tract infection usually presents with fever.
Here, we report two PFAPA cases in patients with VUR in whom recurrent episodes of fever were misdiagnosed as UTI.
Keywords: PFAPA Syndrome; Periodic Fever Syndrome; Vesico-Ureteral Reflux; Urinary Tract Infections; Child.
How to Cite
References
Marshall GS, Edwards KM, Butler J, Lawton AR. Syndrome of periodic fever, pharyngitis, and aphthous stomatitis. J Pediatr 1987;110:43-6.
Feder HM Jr, Bialecki CA. Periodic fever associated with aphthous stomatitis, pharyngitis and cervical adenitis. Ped Infect Dis J 1989;8:186-7.
Rubin LG, Kamani N. Syndrome of periodic fever and pharyngitis (letter). J Pediatr 1987;110:307.
Feder HM Jr. Cimetidine treatment for periodic fever associated with aphthous stomatitis, pharyngitis and cervical adenitis. Ped Infect Dis J 1992;11:318-21.
Marshall GS, Edwards KM. PFAPA syndrome (letter). Ped Infect Dis J1989;8:658-9.
Thomas KT. Periodic fever syndrome in children. J Pediatr 1999;18:68_6.
Hofer MF, Mahlaoui N, Prieur AM. A child with a systemic febrile illness—differential diagnosis and management. Best Pract Res Clin Rheumatol 2006;4:627-40.
Spencer JD, Schwaderer A, McHugh K, Hains DS. Pediatric urinary tract infections: an analysis of hospitalizations, charges, and costs in the USA. Pediatr Nephrol. 2010;25(12):2469–75. PubMed PMID:20711740.
Ransley PG. Vesicoureteric reflux: continuing surgical dilemma. Urology. 1978;12(3):246–55.
Dick PT, Feldman W. Routine diagnostic imaging for childhood urinary tract infections: a systematic overview. J Pediatr.1996;128(1):15–22.
Smellie J, et al. Vesico-ureteric reflux and renal scarring. Kidney Int Suppl. 1975;4:S65–72.
Padeh S, Brezniak N, Zemer D, et al. Periodic fever, aphthous stomatitis, pharyngitis and adenopathy syndrome: clinical characteristics and outcome. J Pediatr 1999;135:98–101.
Padeh S, Brezniak N, Zemer D, et al. Periodic fever, aphthous stomatitis, pharyngitis, and adenopathy syndrome: clinical characteristics and outcome. J Pediatr 1999;135:98-101.
Feder HM Jr. Cimetidine treatment for periodic fever associated with aphthous stomatitis, pharyngitis and cervical adenitis. Pediatr Infect Dis J1992;11:318-21.
- Abstract Viewed: 471 times
- PDF Downloaded: 492 times