Averting the Legacy of Kidney Disease--Focus on Childhood
Journal of Pediatric Nephrology,
Vol. 4 No. 1 (2016),
13 February 2016
World Kidney Day 2016 focuses on kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood. Chronic kidney disease (CKD) in childhood differs from that in adults, as the largest diagnostic group among children includes congenital anomalies and inherited disorders, with glomerulopathies and kidney disease in the setting of diabetes being relatively uncommon. In addition, many children with acute kidney injury will ultimately develop sequelae that may lead to hypertension and CKD in later childhood or in adult life. Children born early or who are small-for date newborns have relatively increased risk for the development of CKD later in life. Persons with a high-risk birth and early childhood history should be watched closely in order to help detect early signs of kidney disease in time to provide effective prevention or treatment. Successful therapy is feasible for advanced CKD in childhood; there is evidence that children fare better than adults, if they receive kidney replacement therapy including dialysis and transplantation, while only a minority of children may require this ultimate intervention Because there are disparities in access to care, effort is needed so that those children with kidney disease, wherever they live, may be treated effectively, irrespective of their geographic or economic circumstances. Our hope is that World Kidney Day will inform the general public, policy makers and caregivers about the needs and possibilities surrounding kidney disease in childhood.
How to Cite
Goldstein S.L. Acute kidney injury in children and its potential consequences in adulthood. Blood Purif 2015;33:131-137.
Harambat J., van Stralen K.J., Kim J.J., Tizard, E.J. Epidemiology of chronic kidney disease in children. Pediatr Nephrol 2012;27:363-373.
Warady B.A., Chadha V. Chronic kidney disease in children: the global perspective. Pediatr Nephrol 2007;22:1999-2009.
Furth S.L., et al. Design and methods of the Chronic Kidney Disease in Children (CKiD) prospective cohort study. Clin J Am Soc Nephrol 2006;1:1006-1015.
Health statistics and information systems: Estimates for 2000–2012. http://www.who.int/healthinfo/global_burden_disease/estimates/en/index1.html.
NAPRTCS Annual Reports https://web.emmes.com/study/ped/annlrept/annlrept.html.
Saran R., et al. US Renal Data System 2014 Annual Data Report: Epidemiology of Kidney Disease in the United States. Am J Kidney Dis 2015;65, A7.
ESPN/ERA-EDTA Registry, European Registry for Children on Renal Replacement Therapy http://www.espn-reg.org/index.jsp.
Ardissino G., et al. Epidemiology of chronic renal failure in children: data from the ItalKid project. Pediatrics 2003;111:e382-387.
Wong, C.J., Moxey-Mims, M., Jerry-Fluker, J., Warady, B.A. & Furth, S.L. CKiD (CKD in children) prospective cohort study: a review of current findings. Am J Kidney Dis 2012;60:1002-1011.
Global Burden of Disease Study 2013 Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. . Lancet. 20134;386:743-800.
Coca S.G., Singanamala, S. & Parikh, C.R. Chronic kidney disease after acute kidney injury: a systematic review and meta-analysis. Kidney Int 2012;81:442-448.
Basu R.K., et al. Assessment of Worldwide Acute Kidney Injury, Renal Angina and Epidemiology in critically ill children (AWARE): study protocol for a prospective observational study. BMC Nephrol 2015;16:24.
Eckardt K.U., et al. Evolving importance of kidney disease: from subspecialty to global health burden. Lancet 2013;382:158-169.
Wuhl E., et al. Timing and outcome of renal replacement therapy in patients with congenital malformations of the kidney and urinary tract. Clin J Am Soc Nephrol 2013;8:67-74.
Group E.T., et al. Strict blood-pressure control and progression of renal failure in children. N Engl J Med 2009;361:1639-1650.
van Stralen, K.J., Borzych-Dużalka, D., Hataya, H. & et al. Survival and clinical outcomes of children starting renal replacement therapy in the neonatal period. Kidney Int 2014:86.
Querfeld U., et al. The Cardiovascular Comorbidity in Children with Chronic Kidney Disease (4C) study: objectives, design, and methodology. Clin J Am Soc Nephrol 2010;5:1642-1648.
Hoy W.E., et al. The early development of the kidney and implications for future health. Journal of developmental origins of health and disease 2010;1:216-233.
Flynn J.T., et al. The effect of abnormal birth history on ambulatory blood pressure and disease progression in children with chronic kidney disease. J Pediatr 2014;165:154-162 e151.
Rodriguez M.M., et al. Histomorphometric analysis of postnatal glomerulogenesis in extremely preterm infants. Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2004;7:17-25.
Abitbol C.L., et al.Long-term follow-up of extremely low birth weight infants with neonatal renal failure. Pediatr Nephrol18 2003:887-893.
Hodgin J.B., Rasoulpour, M., Markowitz, G.S. & D'Agati, V.D. Very low birth weight is a risk factor for secondary focal segmental glomerulosclerosis. Clin J Am Soc Nephrol 2009;4, 71-76.
Verhave J.C., Wetzels, J.F. & van de Kar, N.C. Novel aspects of atypical haemolytic uraemic syndrome and the role of eculizumab. Nephrol Dial Transplant29 2014;Suppl 4, iv131-141.
Torres V.E. Vasopressin receptor antagonists, heart failure, and polycystic kidney disease. Annu Rev Med 2015;66, 195-210.
Jarzembowski T., et al. Impact of non-compliance on outcome after pediatric kidney transplantation: an analysis in racial subgroups. Pediatr Transplant 2004;8, 367-371.
Watson A.R. Non-compliance and transfer from paediatric to adult transplant unit. Pediatr Nephrol 2000;14, 469-472.
Aujoulat I., et al. Non-adherence in adolescent transplant recipients: the role of uncertainty in health care providers. Pediatr Transplant 2011;15, 148-156.
Watson A.R., et al. Transition from pediatric to adult renal services: a consensus statement by the International Society of Nephrology (ISN) and the International Pediatric Nephrology Association (IPNA). Kidney Int 2011;80, 704-707.
Watson A.R., et al. Transition from pediatric to adult renal services: a consensus statement by the International Society of Nephrology (ISN) and the International Pediatric Nephrology Association (IPNA). Pediatr Nephrol 2011;26, 1753-1757.
Gallieni M., et al. The burden of hypertension and kidney disease in Northeast India: the Institute for Indian Mother and Child noncommunicable diseases project. TheScientificWorldJournal 2014;320869.
White A., Wong W., Sureshkumur P. & Singh G. The burden of kidney disease in indigenous children of Australia and New Zealand, epidemiology, antecedent factors and progression to chronic kidney disease. Journal of paediatrics and child health 2010;46:504-509.
Zarocostas J. Need to increase focus on non-communicable diseases in global health, says WHO. BMJ 2010;341, c7065.
Gulland A. WHO agrees to set up body to act on non-communicable diseases. BMJ 2013;346, f3483.
Feehally J. Chronic kidney disease: Health burden of kidney disease recognized by UN. Nat Rev Nephrol 20118, 12-13.
Couser W.G., Remuzzi G., Mendis S. & Tonelli M. The contribution of chronic kidney disease to the global burden of major noncommunicable diseases. Kidney Int 2011;80, 1258-1270.
- Abstract Viewed: 358 times
- PDF Downloaded: 201 times