Original Article

Argon Plasma Coagulation in Treatment of Post Intubation Tracheal Stenosis

Hamidreza Jabbardarjani, Arda Kiani, Negar Sheikhi, Mohammad Reza Masjedi

Journal of Lasers in Medical Sciences, Vol. 2 No. 2 (2011), 28 June 2011, Page 49-53

INTRODUCTION: Acquired tracheal stenosis can be created by various malignant or benign causes. The most common cause of acquired non-malignant tracheal stenosis is endotracheal intubation, even for a short period. Argon plasma coagulation is a non-contact method of thermal hemostasis. Argon plasma coagulation can be used easily and fast and has low depth of penetration. 

METHODS: This study is single blinded. Subjects are patients with tracheal stenosis after endotracheal intubation who were selected by non-probability sampling and were studied from March 2007 to November 2009 in bronchoscopy and laser center of Masih Daneshvari Hospital, Tehran. First, for each patient, a diagnostic flexible bronchoscopy was performed to identify the type, location, and severity of the stenosis. Then, under general anesthesia, patients underwent rigid bronchoscopy. Then, with Argon plasma coagulation device (ERBE VIO 200D) the stenosis was removed as possible. After two weeks, a new PFT (pulmonary function test) was done for checking the obstructive signs.

RESULTS: Of these 34 patients, 24 were asymptomatic for more than 1 year and responded to treatment(70/6%), 5 were asymptomatic for more than 10 months and less than 12 months (14/7%) and 5 did not have asymptomatic periods more than 10 months, and did not respond to treatment. In PFT follow-ups, FEV1 in all patients who were asymptomatic for more than 10 months had a significant progress; therefore, in 27 out of 29 patients at the end of the study, FEV1 was more than 90% and 2 patients had FEV1 of 70-90%.

CONCLUSION: In fact, although the surgical treatment remains the main treatment of tracheal stenosis after intubation (PITS), if this method is not possible for any reason, APC is very useful as a safe and effective method.

Study of Laser Assisted Hatching for Fertility Outcome in Intra Cytoplasmic Sperm Injection and IVF Cycles

Victoria Habibzadeh, Tooraj Reza Mirshekari, Aboozar Ganjizadegan

Journal of Lasers in Medical Sciences, Vol. 2 No. 2 (2011), 28 June 2011, Page 54-58

INTRODUCTION: Implantation of transferred embryos in the uterus after IVF_ICSI cyclesis an important process that less information about it is available. Zona hatching method is a suggested approach for this goal. The aim of this research is about performance of zona hatching by laser.

METHODS: In this study 32 patients that enrolled had IVF/ICSI cycles depend on inclusion criteria of study that they included patients who were more than 35 years old, at least one previous failure of IVF, thickness or hardness of zona pelucida, the laser hatching performed on them. Then the pregnancy test (ß-subunit) was done and patients with a positive result are followed with vaginal ultra sonography.

RESULTS: Our successful results belonged to the patients who had more than 35 years old. So 50% of pregnancy was positive and then 20% about the zona pelucida thickness and minimum results were about the previous failure of IVF/ICSI cycles.

CONCLUSION: Laser hatching on the embryos of women more than 35 years old with IVF/ICSI cycle will optimize pregnancy outcomes

Trans-Ureteral Ureterolithotripsy of Ureteral Calculi:Which is the Best; Pneumatic or Holmium Laser Technique?

Mohammad Reza Razzaghi, Abdollah Razi, Mohammad Mohsen Mazloomfard, Hooman Mokhtarpour, Babak Javanmard, Reza Mohammadi

Journal of Lasers in Medical Sciences, Vol. 2 No. 2 (2011), 28 June 2011, Page 59-62

INTRODUCTION: Our aim was compare of two types of lithotripter include holmium: YAG laser and pneumatic one in transurethral ureterolithotripsy (TUL) for the management of ureteral calculi ≥1 cm.

METHODS: 112 patients with ureteral calculi more than 1 cm were selected in randomized order for pneumatic or holmium: YAG laser transurethral ureterolithotripsy (56 patients in each group). Ultrasonography and intravenous urography were performed for all patients before surgery. Complete clearance and success was defined as the absence of any fragments on post operation KUB and ultrasonography images.

RESULTS: Success rate was 85.7% in pneumatic group and 100% in holmium: YAG laser group (p =0.003). Stone migration up in the pelvicalyceal system was observed only in 8 cases of pneumatic group. No statically differences were observed in terms of patient’s age, hospital stay, and complications between two groups.

CONCLUSION: According to our experience, for ureteral stone larger than 1 Cm treatment with ureteroscopy and laser lithotripsy is a preferring approach with favorable operation time and hospital admission, and no more significant complication.

Intense Pulsed Light and Red Light Photo Rejuvenation for Skin Rejuvenation: A Split Face Clinical Trial

Hamideh Moravvej, Mohammad Saeedi

Journal of Lasers in Medical Sciences, Vol. 2 No. 2 (2011), 28 June 2011, Page 63-66

INTRODUCTION: Intense pulsed light (IPL) has long been used for skin rejuvenation. Photo rejuvenation with red light (with or without photo sensitizer) is a newer noninvasive way for this purpose; but, until now few comparative studies between these modalities have been performed. The aim of this study was to compare efficacy, adverse effects, and compliance of intense pulsed light rejuvenation and red light photo rejuvenation in a homogeneous group of women.

METHODS: In this clinical trial, ten female volunteers with Fitzpatrick skin types I, II, and III were enrolled. Patients underwent 6 sessions of IPL rejuvenation at 4-week intervals on one side, and 30 photo rejuvenation sessions (twice a week) with red light on the other side of their face. Improvement of the skin texture and reduction in the wrinkles were determined in two ways. Firstly, by comparing the photographs, and secondly, by measuring the skin elasticity with Reviscometer MPA 9 system, before and after the procedure.

RESULTS: Both treatments were associated with improvement in the skin texture and wrinkle depth, but red light was more effective on the nasolabial fold and IPL was more effective on the fine wrinkles.

CONCLUSIONS: Red light photo rejuvenation without the use of photosensitizer can be a new, effective and safe procedure for rejuvenation

Evaluation of Efficacy of Intense Pulsed Light (IPL) System in the Treatment of Facial Acne Vulgaris:Comparision of Different Pulse Durations; A Pilot Study

Behrooz Barikbin, Azin Ayatollahi, Shima Younespour, Somayeh Hejazi

Journal of Lasers in Medical Sciences, Vol. 2 No. 2 (2011), 28 June 2011, Page 67-72

INTRODUCTION: Adequate control of acne is difficult, regardless of the various conventional modalities. Intense Pulsed Light (IPL) system is one of the emerging options that are become increasingly useful.

METHODS: To achieve the best IPL parameters we evaluated the efficacy and tolerability of IPL at 752-nm wavelength, 35 j/cm2 fluence, 55-ms pulse duration in comparison with 572-nm wavelength, 35 j/cm2 fluence, 101-ms pulse duration, in a 5 week, controlled, double-blind, split-face clinical trial. Final assessment was made by comparison of the changes in inflammatory and non-inflammatory acne lesions count and the Acne Global Severity Scale (AGSS) between two groups, based on standardized photography.

RESULT: Fifteen female patients, with mean age of 23.53±2.47 years (range 20-28) completed the 5-week therapy period. For both therapies, significant reductions (approximately 30%) in the comedone and inflammatory lesions count were observed (p=0.0024). There was no significant difference in the efficacy of the two treatments in reducing the percentage of comedone and inflammatory lesions count from baseline to 5th week (p=0.76 and p=0.61, respectively). Based on acne global severity scale (AGSS), no significant difference in the severity of acne lesions of the two treatments was observed at 5th-week visit (p=0.26).

CONCLUSION: Considering the lack of significant difference between the two treatments and since greater risks are associated with lower pulse duration, the use of longer pulse durations is recommended, especially in darker skin phenotype. Further studies with larger number of patients are required to fully comparison of efficacy of these parameters in IPL systems for acne vulgaris.

Review Article

The Use of Intense Pulsed Light (IPL) for the Treatment of Vascular Lesions

Behrooz Barikbin, Azin Ayatollahi, Somayeh Hejazi, Zahra Saffarian, Sara Zamani

Journal of Lasers in Medical Sciences, Vol. 2 No. 2 (2011), 28 June 2011, Page 73-81

 According to the English literature, various lasers and light sources (i,g. argon ion lasers, pulsed KTP lasers, diode lasers and Nd:YAG lasers, pulsed dye laser(PDL), intense pulsed light sources (IPLS) are applicable for the treatment of different vascular lesions. These conditions are the most important indication for laser therapy. This review summarizes the current literature on IPL with regard to the treatment of vascular lesions

Case Report

Clinical Application of 810nm Diode Laser and Low Level Laser Therapy for Treating an Endodontic Problem A Case Presentation

Mohammad Asnaashari, Nikou Asnaashari

Journal of Lasers in Medical Sciences, Vol. 2 No. 2 (2011), 28 June 2011, Page 82-86

The standards of endodontics have constantly been raised in the last 25 years by practitioners’ researches and their interest. Most of the scientists believe the recent developments and the use of lasers as the most exciting achievement in endodontic treatment. Nowadays, lasers are being used in endodontics to improve the prognosis of the root-filled teeth. The Implement of suitable wavelengths, together with conventional methods, can effectively sterilize the canal, dentin and periapical regions. This article describes a successful treatment of an endodontic case using 810nm diode laser and low Level Laser and sixteen months follow-up to improve healling of the edema.

Urethroscopic Holmium: YAG Laser Ablation of Large Urethral Stone after Two-Stage Urethroplasty

Seyed Jalil Hosseini, Hooman Mokhtarpour, Alireza Bagher Tabrizi, Amin Hasanzadeh

Journal of Lasers in Medical Sciences, Vol. 2 No. 2 (2011), 28 June 2011, Page 87-88

Hairball in a urethral diverticulum has rarely been reported. These hairballs are usually formed in the diverticulum coated with a hair bearing epithelium and can lead to urinary obstruction or infection. Using laser is a safe way to ablate such stones.