Kikuchi-Fujimoto Disease in an Iranian Woman; a Rare but Important Cause of Lymphadenopathy
学术急诊医学档案,
卷 7 编号 1 (2019),
1 一月 2019
,
第 e3 页
https://doi.org/10.22037/aaem.v7i1.3
摘要
Kikuchi-Fujimoto Disease (KFD), is a rare and self-limited condition of histiocytic necrotizing lymphadenitis, which typically presents as fever and lymphadenopathy. We describe a case of KFD in an Iranian woman. Due to low incidence and high importance, awareness of this disease is necessary for clinicians for early diagnosis and appropriate treatment. A 26-year-old woman was admitted to our hospital with a 3-week history of fever and lymphadenopathy. On physical examination, she had three separate enlarged lymph nodes on the right side of her neck. In laboratory tests that were carried out, she had mild anemia and an increase in C-reactive protein (CRP) level, erythrocyte sedimentation rate (ESR) and lactate dehydrogenase (LDH) level, while other tests were normal. Ultasound (U/S) guided core needle lymph node biopsy was performed and based on the histological finding, diagnosis of Kikuchi-Fujimoto disease was made. The patient was managed supportively and with prednisolone. She symptomatically improved and was discharged with no follow up. Although the incidence of KFD is rare, it must be considered as a differential diagnosis of lymphadenopathy especially in tuberculosis-endemic areas like our country-Iran. Moreover, it is necessary that physicians are aware of this disease in order to minimize unnecessary evaluation and toxic treatment.- Histiocytic necrotizing lymphadenitis
- Fever
- lymphadenopathy
##submission.howToCite##
参考
Shahid S, Alam SH, Hadley I. An Unusual Presentation of Kikuchi-Fujimoto Disease with Recurrent Subdural Effusion. Cureus. 2018;10(3):e2302.
Lamzaf L, Harmouche H, Maamar M, Adnaoui M, Aouni M, Tazi Mezalek Z. Kikuchi-Fujimoto disease: report of 4 cases and review of the literature. European annals of otorhinolaryngology, head and neck diseases. 2014;131(6):329-32.
Szczurowska A, Pawlowski T, Halon A, Skoczynska A. A white man with Kikuchi-Fujimoto disease mimicking lymphoma, preceded by frequent episodes of tonsillitis: a case report. Journal of medical case reports. 2017;11(1):39.
Jamal A-B. Kikuchi Fujimoto Disease. Clinical Medicine Insights Arthritis and Musculoskeletal Disorders. 2012;5:63.
Kido H, Kano O, Hamai A, Masuda H, Fuchinoue Y, Nemoto M, et al. Kikuchi-Fujimoto disease (histiocytic necrotizing lymphadenitis) with atypical encephalitis and painful testitis: a case report. BMC Neurology. 2017;17:22.
Zaghloul A, Iorgoveanu C, Polio A, Desai A. Kikuchi-Fujimoto Disease in a Young African American Male. Cureus. 2018;10(4).
Mrówka-Kata K, Kata D, Kyrcz-Krzemień S, Sowa P. Kikuchi-Fujimoto disease as a rare cause of lymphadenopathy--two cases report and review of current literature. Otolaryngologia polska= The Polish otolaryngology. 2013;67(1):1.
Găman M, Vlădăreanu A-M, Dobrea C, Onisâi M, Marinescu C, Voican I, et al. A Challenging Case of Kikuchi-Fujimoto Disease Associated with Systemic Lupus Erythematosus and Review of the Literature. Case Reports in Hematology. 2018;2018.
Punjabi RK. Necrotizing lymphadenitis: If not tuberculosis then what? Journal of family medicine and primary care. 2018;7(1):255.
Dalugama C, Gawarammana IB. Fever with lymphadenopathy–Kikuchi Fujimoto disease, a great masquerader: a case report. Journal of medical case reports. 2017;11.
Srikantharajah M, Mahendra P, Vydianath B, Lowe GC. Case Report: Kikuchi-Fujimoto disease: a rare but important differential diagnosis for lymphadenopathy. BMJ case reports. 2014;2014.
Ranabhat S, Tiwari M, Kshetri J, Maharjan S, Osti BP. An uncommon presentation of Kikuchi Fujimoto disease: a case report with literature review. BMC Research Notes. 2015;8.
Lame C, Loum B, Fall A, Cucherousset J, Ndiaye A. Kikuchi-Fujimoto disease, a rare cause of lymphadenopathy in Africa. Description of the first case in Senegal and review of the literature. European annals of otorhinolaryngology, head and neck diseases. 2017;134(5):347.
Pepe F, Disma S, Teodoro C, Pepe P, Magro G. Kikuchi-Fujimoto disease: a clinicopathologic update. Pathologica. 2016;108(3):120.
- 摘要 ##plugins.themes.ojsPlusA.frontend.article.viewed##: 546 ##plugins.themes.ojsPlusA.frontend.article.times##
- PDF (English) ##plugins.themes.ojsPlusA.frontend.article.downloaded##: 320 ##plugins.themes.ojsPlusA.frontend.article.times##
- HTML (English) ##plugins.themes.ojsPlusA.frontend.article.downloaded##: 136 ##plugins.themes.ojsPlusA.frontend.article.times##
##plugins.themes.ojsPlusA.frontend.article.downloadstatastics##
##plugins.block.makeSubmission.linkLabel##
SJR
COPE
