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学术急诊医学档案

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  3. 卷 5 编号 1 (2017): Continuous volume
  4. Case Report

卷 5 编号 1 (2017)

一月 2017

Paradoxical Embolism due to Persistent Foramen Ovale; a Case Report

  • Dormar David Barrios
  • Jonathan Roncancio
  • Albert Alejandro Avila
  • Jaime Andrés Alvarado
  • Ana Cristina Montenegro

学术急诊医学档案, 卷 5 编号 1 (2017), 1 一月 2017 , 第 e46 页
https://doi.org/10.22037/aaem.v5i1.171 已出版: 2017-01-14

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摘要

The mean percentage of cryptogenic strokes among ischemic strokes is 31%, of which one-third may be associated with patent foramen ovale. The foramen ovale is required for blood flow through the fetal atrial septum.  It is formed as of the fourth week of gestation, and this leads to right-left interatrial shunt that allows the passage of oxygenated blood to systemic circulation. In 75% of cases, its closure is complete by 2 years of age, but it may persist in 25% of patients. We present the case of a patient with paradoxical embolism in the lower extremities and ischemic stroke in the clinical context of a patent foramen ovale.
关键词:
  • Embolism
  • Paradoxical
  • blood coagulation
  • Anticoagulants
  • emergency department
  • venous thromboembolism
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Barrios DD, Roncancio J, Avila AA, Alvarado JA, Montenegro AC. Paradoxical Embolism due to Persistent Foramen Ovale; a Case Report. Arch Acad Emerg Med [网际网络]. 2017年1月14日 [见引于 2026年8月24日];5(1):e46. 载于: https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/171
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参考

Gupta V, Yesilbursa D, Huang WY, Aggarwal K, Gomez C, Patel V, et al. Patent foramen ovale in a large population of ischemic stroke patients: diagnosis, age distribution, gender, and race. Echocardiography (Mount Kisco, NY). 2008;25(2):217-27.

Heuchan AM, Clyman RI. Managing the patent ductus arteriosus: current treatment options. Archives of disease in childhood Fetal and neonatal edition. 2014;99(5):F431-6.

Omar H, Huang C, Miller J, Mangar D, Kabemba A, Camporesi E. Simultaneous pulmonary embolism and cerebrovascular stroke. Herz. 2013;38(8):884-6.

Podroužková H, Horváth V, Hlinomaz O, Bedan J, Bambuch M, Němec P, et al. Embolus entrapped in patent foramen ovale: impending paradoxical embolism. The Annals of thoracic surgery. 2014;98(6):e151-e2.

Windecker S, Stortecky S, Meier B. Paradoxical Embolism. Journal of the American College of Cardiology. 2014;64(4):403-15.

Kent D, Thaler D. The Risk of Paradoxical Embolism (RoPE) Study: developing risk models for application to ongoing randomized trials of percutaneous patent foramen ovale closure for cryptogenic stroke. Trials. 2010;12:185-.

Mohr J, Thompson J, Lazar RM, Levin B, Sacco RL, Furie K, et al. A comparison of warfarin and aspirin for the prevention of recurrent ischemic stroke. New England Journal of Medicine. 2001;345(20):1444-51.

Homma S, Sacco RL, Di Tullio MR, Sciacca RR, Mohr J, Investigators PiCSS. Effect of medical treatment in stroke patients with patent foramen ovale patent foramen ovale in Cryptogenic Stroke Study. Circulation. 2002;105(22):2625-31.

Jiménez D, Aujesky D, Moores L, Gómez V, Martí D, Briongos S, et al. Combinations of prognostic tools for identification of high-risk normotensive patients with acute symptomatic pulmonary embolism. Thorax. 2011;66(1):75-81.

Meyer G, Vicaut E, Danays T, Agnelli G, Becattini C, Beyer-Westendorf J, et al. Fibrinolysis for patients with intermediate-risk pulmonary embolism. New England Journal of Medicine. 2014;370(15):1402-11.

Bova C, Sanchez O, Prandoni P, Lankeit M, Konstantinides S, Vanni S, et al. Identification of intermediate-risk patients with acute symptomatic pulmonary embolism. European Respiratory Journal. 2014;44(3):694-703.

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