The Effect of Oxygen Therapy on Oxidative Stress Index in Patients with Acute Myocardial Infarction; a Letter to the Editor
Archives of Academic Emergency Medicine,
Vol. 7 No. 1 (2019),
1 January 2019
,
Page e2
https://doi.org/10.22037/aaem.v7i1.2
Abstract
Tissue hypoxia is a key factor for cell death after acute myocardial infarction (MI). It seems that increase in the relative oxygen pressure in inhaled air can be an effective treatment option for treating acute MI. However, contradicting findings and results have been published regarding using oxygen therapy in patients with acute MI (1, 2). Some researchers have believed that generation of free radicals, induction of oxidative stress, and damage to cell membrane are among side effects of O2 consumption (3, 4). It has been shown that O2 therapy can increase microvascular resistance, result in a decrease in coronary blood flow and cardiac output, and bring about numerous negative effects such as increase in the risk of arrhythmia and cellular damage (4).- Oxygen Inhalation Therapy
- Oxidative Stress
- Inferior Wall Myocardial Infarction
- Anterior Wall Myocardial Infarction
How to Cite
References
Beasley R, Weatherall M, Aldington S, Mchaffie D, Robinson G. Oxygen therapy in myocardial infarction: an historical perspective. Journal of the Royal Society of Medicine. 2007;100(3):130-3.
Lorgis L, Zeller M, Dentan G, Sicard P, Richard C, Buffet P, et al. The free oxygen radicals test (FORT) to assess circulating oxidative stress in patients with acute myocardial infarction. Atherosclerosis. 2010;213(2):616-21.
Hammond B, Hess ML. The oxygen free radical system: potential mediator of myocardial injury. Journal of the American College of Cardiology. 1985;6(1):215-20.
Weston C. Oxygen therapy in acute myocardial infarction–too much of a good thing? Cochrane Database of Systematic Reviews. 2010(6).
Gill R, Tsung A, Billiar T. Linking oxidative stress to inflammation: Toll-like receptors. Free Radical Biology and Medicine. 2010;48(9):1121-32.
Sharma V, Shukla RK, Saxena N, Parmar D, Das M, Dhawan A. DNA damaging potential of zinc oxide nanoparticles in human epidermal cells. Toxicology letters. 2009;185(3):211-8.
Singhal AB, Benner T, Roccatagliata L, Koroshetz WJ, Schaefer PW, Lo EH, et al. A pilot study of normobaric oxygen therapy in acute ischemic stroke. Stroke. 2005;36(4):797-802.
Ranchord AM, Argyle R, Beynon R, Perrin K, Sharma V, Weatherall M, et al. High-concentration versus titrated oxygen therapy in ST-elevation myocardial infarction: a pilot randomized controlled trial. American heart journal. 2012;163(2):168-75.
Tatarkova Z, Engler I, Calkovska A, Mokra D, Drgova A, Kuka S, et al. Effect of normobaric oxygen treatment on oxidative stress and enzyme activities in guinea pig heart. General physiology and biophysics. 2012;31(2):179-84.
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